South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2626 cruises
Per Person
Total Price
List Grid

Range:

APPLY
Cruise From:
Was £284pp Now: £269pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 03 Dec 2027
  • 3 Nights

Interest free Monthly Payments from JUST £15pp

Cruise From:
Was £284pp Now: £269pp
View cruise
Holiday ID: 100290
Cruise From:
Was £280pp Now: £271pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 20 Nov 2026
  • 3 Nights
Cruise From:
Was £280pp Now: £271pp
View cruise
Holiday ID: 017850
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 08 Feb 2027
  • 4 Nights

Interest free Monthly Payments from JUST £93pp

Cruise From:
£271pp
View cruise
Holiday ID: 024718
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 07 Feb 2027
  • 4 Nights

Interest free Monthly Payments from JUST £95pp

Cruise From:
£271pp
View cruise
Holiday ID: 024779
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 24 Jan 2027
  • 4 Nights
Cruise From:
£271pp
View cruise
Holiday ID: 024791
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 14 Feb 2027
  • 4 Nights

Interest free Monthly Payments from JUST £81pp

Cruise From:
£271pp
View cruise
Holiday ID: 024795
Cruise From:
Was £280pp Now: £271pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 25 Aug 2028
  • 3 Nights
Cruise From:
Was £280pp Now: £271pp
View cruise
Holiday ID: 100514
Cruise From:
Was £281pp Now: £272pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 29 Apr 2027
  • 4 Nights
Cruise From:
Was £281pp Now: £272pp
View cruise
Holiday ID: 069845
Cruise From:
£273pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 19 Mar 2027
  • 3 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
£273pp
View cruise
Holiday ID: 024690
Cruise From:
Was £283pp Now: £274pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 29 Oct 2026
  • 5 Nights
Cruise From:
Was £283pp Now: £274pp
View cruise
Holiday ID: 021784
Cruise From:
£275pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 19 Feb 2027
  • 3 Nights

Interest free Monthly Payments from JUST £75pp

Cruise From:
£275pp
View cruise
Holiday ID: 024725
Cruise From:
Was £290pp Now: £275pp

World-wide 4 Nights From Salvador de Bahia

Salvador de Bahia | Rio de Janeiro | Santos

  • 28 Nov 2026
  • 4 Nights
Cruise From:
Was £290pp Now: £275pp
View cruise
Holiday ID: 067738
Cruise From:
£276pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 06 Dec 2026
  • 4 Nights
Cruise From:
£276pp
View cruise
Holiday ID: 024815
Cruise From:
Was £285pp Now: £276pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 30 Aug 2027
  • 4 Nights
Cruise From:
Was £285pp Now: £276pp
View cruise
Holiday ID: 069880
Cruise From:
Was £286pp Now: £277pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 03 Nov 2026
  • 5 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 021808
Cruise From:
Was £286pp Now: £277pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 06 Mar 2028
  • 4 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069933
Cruise From:
Was £286pp Now: £277pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 10 Mar 2028
  • 3 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069934
Cruise From:
Was £286pp Now: £277pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 17 Mar 2028
  • 3 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069936
Cruise From:
Was £286pp Now: £277pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 24 Mar 2028
  • 3 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069938
Cruise From:
Was £286pp Now: £277pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 31 Mar 2028
  • 3 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069940
Cruise From:
Was £286pp Now: £277pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 21 Apr 2028
  • 3 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069946
Cruise From:
Was £286pp Now: £277pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 24 Apr 2028
  • 4 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069947
Cruise From:
Was £286pp Now: £277pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 28 Apr 2028
  • 3 Nights
Cruise From:
Was £286pp Now: £277pp
View cruise
Holiday ID: 069948
Cruise From:
Was £288pp Now: £279pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 06 Oct 2028
  • 3 Nights
Cruise From:
Was £288pp Now: £279pp
View cruise
Holiday ID: 100526
Cruise From:
£280pp

4 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 15 Feb 2027
  • 4 Nights

Interest free Monthly Payments from JUST £85pp

Cruise From:
£280pp
View cruise
Holiday ID: 024826
Cruise From:
Was £289pp Now: £280pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 14 May 2027
  • 3 Nights
Cruise From:
Was £289pp Now: £280pp
View cruise
Holiday ID: 069849
Cruise From:
Was £289pp Now: £280pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 21 May 2027
  • 3 Nights
Cruise From:
Was £289pp Now: £280pp
View cruise
Holiday ID: 069851
Cruise From:
Was £291pp Now: £282pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 04 Apr 2027
  • 6 Nights
Cruise From:
Was £291pp Now: £282pp
View cruise
Holiday ID: 016063
Cruise From:
£282pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 05 Mar 2027
  • 3 Nights

Interest free Monthly Payments from JUST £63pp

Cruise From:
£282pp
View cruise
Holiday ID: 024707
Cruise From:
£282pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 18 Dec 2026
  • 3 Nights
Cruise From:
£282pp
View cruise
Holiday ID: 024841

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

Our Award Winning Service


Good Housekeeping Reader Recommended 2026
Good Housekeeping Reader Recommended 2026
Best Workplaces in Travel 2026
Best Workplaces in Travel 2026
UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
Travel Weekly Travel Agent Award 2023
Travel Weekly Travel Agent Award 2023
Best Online Travel Agency 2022
Best Online Travel Agency 2022
TTG Top 50 Ocean Travel Agency 2022
TTG Top 50 Ocean Travel Agency 2022
Best Online Agent 2021
Best Online Agent 2021
Best Company 2020
Best Company 2020
Best Online Agent 2019
Best Online Agent 2019
TTG Top 50 Travel Agency 2019
TTG Top 50 Travel Agency 2019
Explore
Blog
About Us
Careers
Contact Us
Cruise118.com Brochures
Frequently Asked Questions
Privacy Policy
Terms and Conditions
Marketing Preferences
Modern Slavery Statement
Cruise Deals
Cruise Deals
Fly Cruise Deals
2026 Cruises
2027 Cruises
All Inclusive Deals
Last Minute Cruise Deals
Cheap Cruise Deals
Family Cruises
Short Cruises
Adult Only Cruises
Cruise Lines
Ambassador Cruise Line
Celebrity Cruises
Disney Cruise Line
Fred Olsen Cruise Lines
MSC Cruises
Norwegian Cruise Line
P&O Cruises
Princess Cruises
Royal Caribbean International
Virgin Voyages
All Cruise Lines
Popular Ships
Celebrity Apex
MSC Virtuosa
MSC Euribia
MSC World Europa
Arvia
Britannia
Iona
Sky Princess
Icon of The Seas
Destinations
Caribbean
Italy
Mediterranean
South America
United Kingdom
All Destinations
Cyber Essentials Plus logo ABTA member
follow us
World Travel Holdings
This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
Sorry, we have been unable to sign you up to receive our emails. Please use an alternative email address or try again later.
You've added to your wishlist. To view, go to Wishlist
Call for Free