South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2626 cruises
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Range:

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Cruise From:
Was £327pp Now: £317pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 21 Jan 2029
  • 6 Nights
Cruise From:
Was £327pp Now: £317pp
View cruise
Holiday ID: 100610
Cruise From:
£370pp

7 Night Ensenada, Cabo & Mazatlan

Los Angeles | Ensenada | Cabo San Lucas | Mazatlán | Los Angeles

  • 19 Feb 2027
  • 7 Nights

Interest free Monthly Payments from JUST £132pp

Cruise From:
£370pp
View cruise
Holiday ID: 024828
Cruise From:
Was £964pp Now: £899pp

World-wide 17 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Mindelo | Las Palmas de Gran Canaria | Arrecife | Málaga | Valencia

  • 07 Mar 2028
  • 17 Nights

Interest free Monthly Payments from JUST £56pp

Cruise From:
Was £964pp Now: £899pp
View cruise
Holiday ID: 102220
Cruise From:
Was £1239pp Now: £1164pp

World-wide 22 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Mindelo | Las Palmas de Gran Canaria | Arrecife | Málaga | Valencia | Palma de Mallorca | Marseille | Genoa | Marseille | Barcelona

  • 07 Mar 2028
  • 22 Nights

Interest free Monthly Payments from JUST £74pp

Cruise From:
Was £1239pp Now: £1164pp
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Holiday ID: 102217
Cruise From:
Was £659pp Now: £635pp

12-Day Panama Canal with Costa Rica & Caribbean

Fort Lauderdale | Curaçao | Cartagena | Colón | Cartagena | Puerto Limón | Celebration Key | Fort Lauderdale

  • 30 Oct 2026
  • 12 Nights
Cruise From:
Was £659pp Now: £635pp
View cruise
Holiday ID: 018879
Cruise From:
£371pp

7 Night Ensenada, Cabo & Mazatlan

San Diego | Ensenada | Cabo San Lucas | Mazatlán | San Diego

  • 28 Feb 2027
  • 7 Nights

Interest free Monthly Payments from JUST £113pp

Cruise From:
£371pp
View cruise
Holiday ID: 024787
Cruise From:
£372pp

7 Night Cabo Overnight & Ensenada

Los Angeles | Cabo San Lucas | Ensenada | Los Angeles

  • 29 Jan 2027
  • 7 Nights
Cruise From:
£372pp
View cruise
Holiday ID: 024724
Cruise From:
£372pp

7 Night Cabo Overnight & Mazatlan

Los Angeles | Mazatlán | Cabo San Lucas | Los Angeles

  • 11 Dec 2026
  • 7 Nights
Cruise From:
£372pp
View cruise
Holiday ID: 024839
Cruise From:
Was £738pp Now: £693pp

World-wide 13 Nights From Civitavecchia

Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia

  • 30 Oct 2026
  • 13 Nights
Cruise From:
Was £738pp Now: £693pp
View cruise
Holiday ID: 049538
Cruise From:
£374pp

7 Night Ensenada, Cabo & La Paz Cruise

San Diego | La Paz | Cabo San Lucas | Ensenada | San Diego

  • 03 Jan 2027
  • 7 Nights
Cruise From:
£374pp
View cruise
Holiday ID: 024771
Cruise From:
£374pp

7 Night Cabo, Vallarta & Mazatlan

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 08 Jan 2027
  • 7 Nights
Cruise From:
£374pp
View cruise
Holiday ID: 024827
Cruise From:
£375pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 24 Jan 2027
  • 7 Nights
Cruise From:
£375pp
View cruise
Holiday ID: 018336
Cruise From:
£375pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 31 Jan 2027
  • 7 Nights
Cruise From:
£375pp
View cruise
Holiday ID: 018337
Cruise From:
£590pp

Panama Canal: Jamaica & Costa Rica

Miami | Great Stirrup Cay | Cartagena | Colón | Gatun Lake | Puerto Limón | Falmouth | Georgetown | Miami

  • 29 Nov 2026
  • 11 Nights
Cruise From:
£590pp
View cruise
Holiday ID: 018113
Cruise From:
£378pp

7 Night Cabo, Mazatlan & La Paz

San Diego | Cabo San Lucas | Mazatlán | La Paz | San Diego

  • 28 Jan 2027
  • 7 Nights
Cruise From:
£378pp
View cruise
Holiday ID: 024781
Cruise From:
Was £335pp Now: £324pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 03 Sep 2028
  • 6 Nights
Cruise From:
Was £335pp Now: £324pp
View cruise
Holiday ID: 100590
Cruise From:
Was £335pp Now: £324pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 17 Sep 2028
  • 6 Nights
Cruise From:
Was £335pp Now: £324pp
View cruise
Holiday ID: 100592
Cruise From:
Was £335pp Now: £324pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 01 Oct 2028
  • 6 Nights
Cruise From:
Was £335pp Now: £324pp
View cruise
Holiday ID: 100594
Cruise From:
Was £335pp Now: £324pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 04 Feb 2029
  • 6 Nights
Cruise From:
Was £335pp Now: £324pp
View cruise
Holiday ID: 100612
Cruise From:
Was £335pp Now: £324pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 18 Feb 2029
  • 6 Nights
Cruise From:
Was £335pp Now: £324pp
View cruise
Holiday ID: 100614
Cruise From:
£380pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 13 Dec 2026
  • 7 Nights
Cruise From:
£380pp
View cruise
Holiday ID: 018330
Cruise From:
£380pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Mazatlán | Puerto Vallarta | Cabo San Lucas | Los Angeles

  • 03 Jan 2027
  • 7 Nights
Cruise From:
£380pp
View cruise
Holiday ID: 018333
Cruise From:
£380pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 10 Jan 2027
  • 7 Nights
Cruise From:
£380pp
View cruise
Holiday ID: 018334
Cruise From:
£380pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 17 Jan 2027
  • 7 Nights
Cruise From:
£380pp
View cruise
Holiday ID: 018335
Cruise From:
£380pp

7 Night Cabo, Vallarta & Mazatlan

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 15 Jan 2027
  • 7 Nights
Cruise From:
£380pp
View cruise
Holiday ID: 024829
Cruise From:
£381pp

7 Night Cabo, Vallarta & Mazatlan

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 26 Feb 2027
  • 7 Nights

Interest free Monthly Payments from JUST £123pp

Cruise From:
£381pp
View cruise
Holiday ID: 024837
Cruise From:
Was £339pp Now: £328pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 16 Dec 2028
  • 6 Nights
Cruise From:
Was £339pp Now: £328pp
View cruise
Holiday ID: 100605
Cruise From:
Was £283pp Now: £274pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 29 Oct 2026
  • 5 Nights
Cruise From:
Was £283pp Now: £274pp
View cruise
Holiday ID: 021784
Cruise From:
Was £398pp Now: £384pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 16 Jan 2027
  • 7 Nights
Cruise From:
Was £398pp Now: £384pp
View cruise
Holiday ID: 017564
Cruise From:
Was £453pp Now: £439pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 13 Mar 2027
  • 8 Nights
Cruise From:
Was £453pp Now: £439pp
View cruise
Holiday ID: 016060

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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