South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2557 cruises
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Was £909pp Now: £854pp

World-wide 15 Nights From Santos

Santos | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Marseille

  • 01 Apr 2027
  • 15 Nights
Cruise From:
Was £909pp Now: £854pp
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Holiday ID: 049687
Cruise From:
Was £17595pp Now: £16539pp

Puerto Williams to Puerto Williams

Puerto Williams | South Georgia Island | Elephant Island | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 22 Dec 2026
  • 15 Nights
Cruise From:
Was £17595pp Now: £16539pp
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Holiday ID: 020408
Cruise From:
Was £268pp Now: £259pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 07 Mar 2027
  • 6 Nights
Cruise From:
Was £268pp Now: £259pp
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Holiday ID: 016059
Cruise From:
Was £20025pp Now: £18823pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 06 Feb 2027
  • 7 Nights
Cruise From:
Was £20025pp Now: £18823pp
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Holiday ID: 020347
Cruise From:
Was £699pp Now: £664pp

Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 18 Apr 2027
  • 7 Nights
Cruise From:
Was £699pp Now: £664pp
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Holiday ID: 049495
Cruise From:
Was £579pp Now: £555pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 13 Feb 2027
  • 7 Nights
Cruise From:
Was £579pp Now: £555pp
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Holiday ID: 017568
Cruise From:
£371pp

7 Night Ensenada, Cabo & Mazatlan

Los Angeles | Ensenada | Cabo San Lucas | Mazatlán | Los Angeles

  • 22 Jan 2027
  • 7 Nights
Cruise From:
£371pp
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Holiday ID: 024840
Cruise From:
Was £253pp Now: £245pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 13 Dec 2026
  • 6 Nights
Cruise From:
Was £253pp Now: £245pp
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Holiday ID: 016047
Cruise From:
Was £939pp Now: £882pp

World-wide 17 Nights From Santos

Santos | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Marseille | Genoa | Civitavecchia

  • 01 Apr 2027
  • 17 Nights
Cruise From:
Was £939pp Now: £882pp
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Holiday ID: 049685
Cruise From:
Was £10965pp Now: £10299pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 06 Mar 2027
  • 7 Nights
Cruise From:
Was £10965pp Now: £10299pp
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Holiday ID: 020351
Cruise From:
Was £371pp Now: £356pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 30 Jan 2027
  • 7 Nights
Cruise From:
Was £371pp Now: £356pp
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Holiday ID: 017566
Cruise From:
£638pp

6 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón

  • 23 Apr 2028
  • 6 Nights

Interest free Monthly Payments from JUST £35pp

Cruise From:
£638pp
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Holiday ID: 057538
Cruise From:
Was £444pp Now: £426pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 27 Mar 2027
  • 7 Nights
Cruise From:
Was £444pp Now: £426pp
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Holiday ID: 017574
Cruise From:
£849pp

7 Night Southern Caribbean Cruise

Cartagena | Willemstad | Oranjestad | Colón | Cartagena

  • 16 Apr 2028
  • 7 Nights

Interest free Monthly Payments from JUST £50pp

Cruise From:
£849pp
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Holiday ID: 057554
Cruise From:
Was £614pp Now: £595pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 19 Dec 2026
  • 8 Nights
Cruise From:
Was £614pp Now: £595pp
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Holiday ID: 016048
Cruise From:
Was £16065pp Now: £15099pp

King George Island to Puerto Williams

King George Island | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 02 Feb 2027
  • 9 Nights
Cruise From:
Was £16065pp Now: £15099pp
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Holiday ID: 020412
Cruise From:
Was £829pp Now: £779pp

World-wide 14 Nights From Santos

Santos | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona

  • 01 Apr 2027
  • 14 Nights
Cruise From:
Was £829pp Now: £779pp
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Holiday ID: 049688
Fly Cruise From:
£1317pp

7 Night Cabo, Vallarta & Mazatlan

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 04 Dec 2026
  • 7 Nights
Fly Cruise From:
£1317pp
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Holiday ID: 024845
Cruise From:
Was £9018pp Now: £8657pp

7 Night Galapagos Inner Loop Itinerary - Christmas

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 17 Dec 2028
  • 7 Nights
Cruise From:
Was £9018pp Now: £8657pp
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Holiday ID: 071693
Cruise From:
Was £9470pp Now: £9091pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 07 Mar 2027
  • 7 Nights
Cruise From:
Was £9470pp Now: £9091pp
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Holiday ID: 026822
Cruise From:
£641pp

7 Nt Cabo, Vallarta & Mazatlan Holiday

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 28 Dec 2026
  • 7 Nights
Cruise From:
£641pp
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Holiday ID: 024830
Cruise From:
Was £1433pp Now: £1361pp

Panama Canal: Los Angeles to Miami

Los Angeles | Cabo San Lucas | Puerto Quetzal | Puntarenas | Panama City | Cartagena | Miami

  • 27 Nov 2027
  • 17 Nights

Interest free Monthly Payments from JUST £153pp

Cruise From:
Was £1433pp Now: £1361pp
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Holiday ID: 072989
Cruise From:
£220pp

7 Night Cabo Overnight & Mazatlan

Los Angeles | Mazatlán | Cabo San Lucas | Los Angeles

  • 11 Dec 2026
  • 7 Nights
Cruise From:
£220pp
View cruise
Holiday ID: 024839
Fly Cruise From:
Was £9590pp Now: £9199pp

Panama Canal & the Americas

Valparaiso | Iquique | Callao | Fuerte Amador | Port Antonio | Inagua | San Salvador Island | New York

  • 10 Apr 2029
  • 19 Nights
Fly Cruise From:
Was £9590pp Now: £9199pp
View cruise
Holiday ID: 081293
Fly Cruise From:
Was £14381pp Now: £12895pp

Punta Arenas to Puerto Williams

Punta Arenas | South Shetland Islands | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 02 Feb 2027
  • 10 Nights
Fly Cruise From:
Was £14381pp Now: £12895pp
View cruise
Holiday ID: 020260
Cruise From:
Was £1596pp Now: £1516pp

Panama Canal: Miami to Los Angeles

Miami | Cartagena | Colón | Puntarenas | Puerto Quetzal | Cabo San Lucas | Los Angeles

  • 26 Mar 2027
  • 16 Nights
Cruise From:
Was £1596pp Now: £1516pp
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Holiday ID: 049493
Cruise From:
Was £5429pp Now: £5211pp

22-Day South America & Antarctica

Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Antarctic Experience | Ushuaia | Punta Arenas | Puerto Chacabuco | Puerto Montt | San Antonio

  • 30 Jan 2028
  • 22 Nights
Cruise From:
Was £5429pp Now: £5211pp
View cruise
Holiday ID: 070806
Cruise From:
£229pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 11 Dec 2026
  • 3 Nights
Cruise From:
£229pp
View cruise
Holiday ID: 024699
Cruise From:
Was £10250pp Now: £9635pp

Puerto Williams to King George Island

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | King George Island

  • 25 Nov 2026
  • 9 Nights
Cruise From:
Was £10250pp Now: £9635pp
View cruise
Holiday ID: 037231
Cruise From:
£741pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Oranjestad | Colón

  • 15 Apr 2028
  • 7 Nights

Interest free Monthly Payments from JUST £43pp

Cruise From:
£741pp
View cruise
Holiday ID: 057556

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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