South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2626 cruises
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Was £759pp Now: £732pp

12-Day Panama Canal with Costa Rica & Caribbean

Fort Lauderdale | Aruba | Cartagena | Colón | Cartagena | Puerto Limón | Celebration Key | Fort Lauderdale

  • 22 Jan 2027
  • 12 Nights
Cruise From:
Was £759pp Now: £732pp
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Holiday ID: 018886
Cruise From:
Was £378pp Now: £366pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 05 Mar 2028
  • 6 Nights
Cruise From:
Was £378pp Now: £366pp
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Holiday ID: 039197
Cruise From:
Was £1179pp Now: £1099pp

World-wide 18 Nights From Santos

Santos | Rio de Janeiro | Salvador de Bahia | Maceió | Santa Cruz de Tenerife | Casablanca | Valencia | Barcelona | Naples

  • 19 Mar 2028
  • 18 Nights

Interest free Monthly Payments from JUST £68pp

Cruise From:
Was £1179pp Now: £1099pp
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Holiday ID: 102207
Cruise From:
£672pp

11-day Cruise on Norwegian Sun

Miami | Falmouth | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 02 Jan 2027
  • 11 Nights
Cruise From:
£672pp
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Holiday ID: 018116
Cruise From:
Was £316pp Now: £306pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 01 Apr 2027
  • 5 Nights
Cruise From:
Was £316pp Now: £306pp
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Holiday ID: 021799
Cruise From:
Was £916pp Now: £861pp

World-wide 14 Nights From Tarragona

Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro | Santos

  • 02 Nov 2026
  • 14 Nights
Cruise From:
Was £916pp Now: £861pp
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Holiday ID: 049543
Cruise From:
Was £254pp Now: £246pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 13 Nov 2028
  • 4 Nights
Cruise From:
Was £254pp Now: £246pp
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Holiday ID: 100531
Cruise From:
Was £919pp Now: £863pp

World-wide 14 Nights From Santos

Santos | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona

  • 01 Apr 2027
  • 14 Nights

Interest free Monthly Payments from JUST £236pp

Cruise From:
Was £919pp Now: £863pp
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Holiday ID: 049688
Cruise From:
Was £449pp Now: £433pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 28 Nov 2026
  • 7 Nights
Cruise From:
Was £449pp Now: £433pp
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Holiday ID: 017557
Cruise From:
Was £449pp Now: £433pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 27 Feb 2027
  • 7 Nights
Cruise From:
Was £449pp Now: £433pp
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Holiday ID: 017570
Cruise From:
Was £989pp Now: £929pp

World-wide 15 Nights From Santos

Santos | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Marseille

  • 01 Apr 2027
  • 15 Nights
Cruise From:
Was £989pp Now: £929pp
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Holiday ID: 049687
Cruise From:
Was £958pp Now: £929pp

Journeys - 15-Day South America

Long Beach | Acapulco | Manta | Callao | Coquimbo | San Antonio

  • 04 Jan 2027
  • 15 Nights
Cruise From:
Was £958pp Now: £929pp
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Holiday ID: 092825
Cruise From:
Was £1029pp Now: £992pp

16-Day Panama Canal - Ocean to Ocean

Fort Lauderdale | Cartagena | Fuerte Amador | Puntarenas | Puerto Chiapas | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 04 Apr 2027
  • 16 Nights
Cruise From:
Was £1029pp Now: £992pp
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Holiday ID: 018824
Cruise From:
Was £512pp Now: £496pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 11 Dec 2027
  • 8 Nights
Cruise From:
Was £512pp Now: £496pp
View cruise
Holiday ID: 069780
Cruise From:
Was £256pp Now: £248pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 10 Jan 2028
  • 4 Nights
Cruise From:
Was £256pp Now: £248pp
View cruise
Holiday ID: 069918
Cruise From:
Was £256pp Now: £248pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 17 Jan 2028
  • 4 Nights
Cruise From:
Was £256pp Now: £248pp
View cruise
Holiday ID: 069920
Cruise From:
Was £256pp Now: £248pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 24 Jan 2028
  • 4 Nights
Cruise From:
Was £256pp Now: £248pp
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Holiday ID: 069922
Cruise From:
Was £256pp Now: £248pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 31 Jan 2028
  • 4 Nights
Cruise From:
Was £256pp Now: £248pp
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Holiday ID: 069924
Cruise From:
Was £513pp Now: £497pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 07 Nov 2026
  • 8 Nights
Cruise From:
Was £513pp Now: £497pp
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Holiday ID: 016042
Cruise From:
£435pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 21 Feb 2027
  • 7 Nights

Interest free Monthly Payments from JUST £194pp

Cruise From:
£435pp
View cruise
Holiday ID: 018340
Cruise From:
Was £1588pp Now: £1492pp

World-wide 24 Nights From Santos

Santos | Rio de Janeiro | Maceió | Mindelo | Funchal | Lisbon | Casablanca | Málaga | Palma de Mallorca | Barcelona | Marseille | Genoa | Naples

  • 07 Mar 2027
  • 24 Nights
Cruise From:
Was £1588pp Now: £1492pp
View cruise
Holiday ID: 080874
Cruise From:
Was £1459pp Now: £1371pp

World-wide 22 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Ajaccio | Civitavecchia | Corfu | Bari | Trieste

  • 31 Mar 2027
  • 22 Nights
Cruise From:
Was £1459pp Now: £1371pp
View cruise
Holiday ID: 049699
Cruise From:
Was £193pp Now: £187pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 21 Dec 2026
  • 3 Nights
Cruise From:
Was £193pp Now: £187pp
View cruise
Holiday ID: 017828
Cruise From:
Was £929pp Now: £873pp

World-wide 14 Nights From Southampton

Southampton | Gijón | Vigo | Lisbon | Funchal | Maceió

  • 06 Nov 2027
  • 14 Nights

Interest free Monthly Payments from JUST £74pp

Cruise From:
Was £929pp Now: £873pp
View cruise
Holiday ID: 102180
Cruise From:
Was £1069pp Now: £999pp

World-wide 16 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Santa Cruz de Tenerife | Tangier | Barcelona

  • 04 Apr 2027
  • 16 Nights
Cruise From:
Was £1069pp Now: £999pp
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Holiday ID: 049679
Cruise From:
Was £1599pp Now: £1499pp

World-wide 24 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Las Palmas de Gran Canaria | Arrecife | Funchal | Cádiz | La Coruña | Bilbao | La Rochelle | Brest | Cherbourg | Warnemünde

  • 01 Apr 2028
  • 24 Nights

Interest free Monthly Payments from JUST £92pp

Cruise From:
Was £1599pp Now: £1499pp
View cruise
Holiday ID: 102222
Cruise From:
Was £516pp Now: £500pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 06 May 2028
  • 8 Nights
Cruise From:
Was £516pp Now: £500pp
View cruise
Holiday ID: 100573
Cruise From:
Was £387pp Now: £375pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 15 Apr 2029
  • 6 Nights
Cruise From:
Was £387pp Now: £375pp
View cruise
Holiday ID: 100622
Cruise From:
£438pp

7 Night Cabo, Vallarta & Mazatlan

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 12 Mar 2027
  • 7 Nights

Interest free Monthly Payments from JUST £123pp

Cruise From:
£438pp
View cruise
Holiday ID: 024817
Cruise From:
Was £779pp Now: £751pp

12-Day Southern Caribbean with Panama

Fort Lauderdale | Aruba | Cartagena | Colón | Puerto Limón | Grand Cayman | Cozumel | Fort Lauderdale

  • 13 Jan 2028
  • 12 Nights

Interest free Monthly Payments from JUST £55pp

Cruise From:
Was £779pp Now: £751pp
View cruise
Holiday ID: 053209

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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