South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2628 cruises
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Cruise & Stay

2027 Rio Carnaval Cruise: Bridgetown, Ile Royale & Rio De Janeiro with Barbados & Rio Stays

Holiday prices from:
Was £4899pp Now: £4799pp

2027 Rio Carnaval Cruise: Bridgetown, Ile Royale & Rio De Janeiro with Barbados & Rio Stays

Bridgetown | Scarborough | Isle Royale | Belem | Recife | Salvador de Bahia | Buzios | Rio de Janeiro

  • 23 Jan 2027
  • 18 Nights
  • 4* hotel stays in Barbados & Rio De Janeiro
  • 13-night more-inclusive cruise
  • Return flights including luggage allowance
  • Select private overseas transfers
Holiday prices from:
Was £4899pp Now: £4799pp
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Cruise & Stay

Cruise118.com Exclusive Savings! Patagonia & Argentina Cruise with Buenos Aires Stay

Holiday prices from:
£3899pp

Cruise118.com Exclusive Savings! Patagonia & Argentina Cruise with Buenos Aires Stay

Buenos Aires | Montevideo | Port Stanley | Ushuaia | Punta Arenas | Puerto Madryn | Punta del Este | Buenos Aires

  • 09 Feb 2028
  • 19 Nights
  • Three-night 4* hotel stay in Buenos Aires
  • Return flights with luggage allowance
  • Private overseas transfers
  • 14-night All-inclusive cruise with Classic Drinks & WiFi
Holiday prices from:
£3899pp
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Cruise From:
Was £162pp Now: £157pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 07 Dec 2026
  • 4 Nights
Cruise From:
Was £162pp Now: £157pp
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Holiday ID: 017827
Cruise From:
Was £176pp Now: £170pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 17 Dec 2026
  • 3 Nights
Cruise From:
Was £176pp Now: £170pp
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Holiday ID: 021803
Cruise From:
Was £177pp Now: £171pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 14 Dec 2026
  • 4 Nights
Cruise From:
Was £177pp Now: £171pp
View cruise
Holiday ID: 017810
Cruise From:
Was £179pp Now: £173pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 04 Dec 2026
  • 3 Nights
Cruise From:
Was £179pp Now: £173pp
View cruise
Holiday ID: 017852
Cruise From:
Was £188pp Now: £182pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 30 Nov 2026
  • 4 Nights
Cruise From:
Was £188pp Now: £182pp
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Holiday ID: 017809
Cruise From:
£182pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 30 Nov 2026
  • 4 Nights
Cruise From:
£182pp
View cruise
Holiday ID: 024694
Cruise From:
£182pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 26 Oct 2026
  • 4 Nights
Cruise From:
£182pp
View cruise
Holiday ID: 024712
Cruise From:
£182pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 16 Nov 2026
  • 4 Nights
Cruise From:
£182pp
View cruise
Holiday ID: 024732
Cruise From:
Was £193pp Now: £187pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 21 Dec 2026
  • 3 Nights
Cruise From:
Was £193pp Now: £187pp
View cruise
Holiday ID: 017828
Cruise From:
Was £194pp Now: £188pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 03 Jan 2027
  • 4 Nights
Cruise From:
Was £194pp Now: £188pp
View cruise
Holiday ID: 021791
Cruise From:
£197pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 19 Oct 2026
  • 4 Nights
Cruise From:
£197pp
View cruise
Holiday ID: 024726
Cruise From:
£198pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 29 Nov 2026
  • 4 Nights
Cruise From:
£198pp
View cruise
Holiday ID: 024812
Cruise From:
Was £209pp Now: £202pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 11 Dec 2026
  • 3 Nights
Cruise From:
Was £209pp Now: £202pp
View cruise
Holiday ID: 017853
Cruise From:
£204pp

7 Night Ensenada, Cabo & La Paz Cruise

San Diego | Ensenada | Cabo San Lucas | La Paz | San Diego

  • 18 Oct 2026
  • 7 Nights
Cruise From:
£204pp
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Holiday ID: 024793
Cruise From:
Was £212pp Now: £205pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 31 Jan 2027
  • 4 Nights
Cruise From:
Was £212pp Now: £205pp
View cruise
Holiday ID: 021794
Cruise From:
Was £218pp Now: £211pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 12 Jan 2027
  • 5 Nights
Cruise From:
Was £218pp Now: £211pp
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Holiday ID: 021811
Cruise From:
Was £222pp Now: £215pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 09 Feb 2027
  • 5 Nights
Cruise From:
Was £222pp Now: £215pp
View cruise
Holiday ID: 021809
Cruise From:
Was £223pp Now: £216pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 28 Dec 2026
  • 3 Nights
Cruise From:
Was £223pp Now: £216pp
View cruise
Holiday ID: 017812
Cruise From:
Was £223pp Now: £216pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 07 Jan 2027
  • 5 Nights
Cruise From:
Was £223pp Now: £216pp
View cruise
Holiday ID: 021792
Cruise From:
£217pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 04 Jan 2027
  • 3 Nights
Cruise From:
£217pp
View cruise
Holiday ID: 024711
Cruise From:
Was £226pp Now: £219pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 12 Dec 2026
  • 5 Nights
Cruise From:
Was £226pp Now: £219pp
View cruise
Holiday ID: 021788
Cruise From:
Was £227pp Now: £220pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 28 Feb 2027
  • 4 Nights
Cruise From:
Was £227pp Now: £220pp
View cruise
Holiday ID: 021796
Cruise From:
£221pp

3 Night Ensenada Cruise

San Diego | Ensenada | San Diego

  • 15 Oct 2026
  • 3 Nights
Cruise From:
£221pp
View cruise
Holiday ID: 024794
Cruise From:
Was £230pp Now: £223pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 04 Feb 2027
  • 5 Nights
Cruise From:
Was £230pp Now: £223pp
View cruise
Holiday ID: 021805
Cruise From:
Was £231pp Now: £224pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 01 Nov 2026
  • 6 Nights
Cruise From:
Was £231pp Now: £224pp
View cruise
Holiday ID: 016020
Cruise From:
£226pp

7 Night Ensenada, Cabo & La Paz Cruise

San Diego | La Paz | Cabo San Lucas | Ensenada | San Diego

  • 25 Oct 2026
  • 7 Nights
Cruise From:
£226pp
View cruise
Holiday ID: 024805
Cruise From:
Was £234pp Now: £226pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 07 Jan 2028
  • 3 Nights
Cruise From:
Was £234pp Now: £226pp
View cruise
Holiday ID: 069917

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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