South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2558 cruises
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Was £8474pp Now: £8219pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 05 Mar 2027
  • 13 Nights
Cruise From:
Was £8474pp Now: £8219pp
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Holiday ID: 099501
Cruise From:
Was £8474pp Now: £8219pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 05 Feb 2027
  • 13 Nights
Cruise From:
Was £8474pp Now: £8219pp
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Holiday ID: 099776
Cruise From:
Was £7688pp Now: £7457pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 06 Jul 2027
  • 10 Nights
Cruise From:
Was £7688pp Now: £7457pp
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Holiday ID: 099126
Cruise From:
Was £11669pp Now: £11318pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 28 Jan 2027
  • 15 Nights
Cruise From:
Was £11669pp Now: £11318pp
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Holiday ID: 099163
Cruise From:
Was £291pp Now: £282pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 16 Mar 2029
  • 3 Nights
Cruise From:
Was £291pp Now: £282pp
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Holiday ID: 100559
Cruise From:
Was £446pp Now: £432pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 06 Aug 2028
  • 6 Nights
Cruise From:
Was £446pp Now: £432pp
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Holiday ID: 100586
Cruise From:
Was £269pp Now: £260pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 12 Feb 2029
  • 4 Nights
Cruise From:
Was £269pp Now: £260pp
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Holiday ID: 100550
Fly Cruise From:
£38147pp

Ultimate Antarctica & the Fjords of Southern Chile

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Cape Horn | Chilean Fjords | Aguila Glacier | Tuckers Islets | Paraty | Admiralty Bay | Punta Arenas | Isla Pinguino | Punta Piramides | Montevideo | Buenos Aires

  • 27 Feb 2028
  • 28 Nights
Fly Cruise From:
£38147pp
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Holiday ID: 091863
Cruise From:
£294pp

4 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 06 Mar 2028
  • 4 Nights

Interest free Monthly Payments from JUST £12pp

Cruise From:
£294pp
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Holiday ID: 098638
Cruise From:
Was £250pp Now: £242pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 11 Dec 2028
  • 4 Nights
Cruise From:
Was £250pp Now: £242pp
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Holiday ID: 100539
Cruise From:
Was £9402pp Now: £9119pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 03 Mar 2028
  • 13 Nights
Cruise From:
Was £9402pp Now: £9119pp
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Holiday ID: 099106
Cruise From:
Was £617pp Now: £598pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 24 Mar 2029
  • 8 Nights
Cruise From:
Was £617pp Now: £598pp
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Holiday ID: 100619
Cruise From:
Was £46589pp Now: £43793pp

World-wide 86 Nights From Valparaiso

Valparaiso | Hangaroa | Pitcairn Island | Papeete | Moorea | Aitutaki | Rarotonga | Bay of Islands | Auckland | Tauranga | Christchurch | Dunedin | Hobart | Sydney | Nouméa | Luganville | Pago Pago | Apia | Honolulu | Los Angeles | Cabo San Lucas | Puntarenas | Balboa (Panama City) | La Romana | Road Town | Philipsburg | Las Palmas de Gran Canaria | Ibiza | Naples | Civitavecchia | Genoa | Marseille

  • 10 Feb 2027
  • 86 Nights
Cruise From:
Was £46589pp Now: £43793pp
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Holiday ID: 067033
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15-Day World Cruise Segment - Panama Canal

Fort Lauderdale | Cartagena | Acajutla | Puerto Chiapas | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 28 Apr 2028
  • 15 Nights

Interest free Monthly Payments from JUST £90pp

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Holiday ID: 099752
Cruise From:
£271pp

4 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 28 Feb 2028
  • 4 Nights

Interest free Monthly Payments from JUST £10pp

Cruise From:
£271pp
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Holiday ID: 098642
Cruise From:
Was £7688pp Now: £7457pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 03 Aug 2027
  • 10 Nights
Cruise From:
Was £7688pp Now: £7457pp
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Holiday ID: 099128
Cruise From:
Was £246pp Now: £238pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 02 Feb 2029
  • 3 Nights
Cruise From:
Was £246pp Now: £238pp
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Holiday ID: 100547
Cruise From:
Was £327pp Now: £317pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 29 Oct 2028
  • 6 Nights
Cruise From:
Was £327pp Now: £317pp
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Holiday ID: 100598
Cruise From:
Was £619pp Now: £594pp

11-Day Baja Peninsula & Sea of Cortez

Los Angeles | Cabo San Lucas | La Paz | Guaymas | Mazatlán | Puerto Vallarta | Los Angeles

  • 13 Oct 2027
  • 11 Nights

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £619pp Now: £594pp
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Holiday ID: 049373
Cruise From:
Was £6192pp Now: £5999pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 24 Mar 2027
  • 8 Nights
Cruise From:
Was £6192pp Now: £5999pp
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Holiday ID: 099498
Cruise From:
Was £6809pp Now: £6599pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 29 Dec 2027
  • 8 Nights
Cruise From:
Was £6809pp Now: £6599pp
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Holiday ID: 099044
Cruise From:
Was £276pp Now: £267pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 18 Dec 2028
  • 3 Nights
Cruise From:
Was £276pp Now: £267pp
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Holiday ID: 100541
Cruise From:
Was £7879pp Now: £7642pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 02 Mar 2027
  • 10 Nights
Cruise From:
Was £7879pp Now: £7642pp
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Holiday ID: 099791
Cruise From:
Was £343pp Now: £332pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 12 Mar 2029
  • 4 Nights
Cruise From:
Was £343pp Now: £332pp
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Holiday ID: 100558
Cruise From:
Was £494pp Now: £479pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 09 Jul 2028
  • 6 Nights
Cruise From:
Was £494pp Now: £479pp
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Holiday ID: 100582
Cruise From:
Was £6328pp Now: £6138pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 19 May 2027
  • 8 Nights
Cruise From:
Was £6328pp Now: £6138pp
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Holiday ID: 099032
Cruise From:
Was £1394pp Now: £1299pp

World-wide 25 Nights From Paranaguá

Paranaguá | Itajai | Ilhabela | Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Mindelo | Las Palmas de Gran Canaria | Arrecife | Málaga | Valencia | Palma de Mallorca | Marseille | Genoa | Marseille | Barcelona

  • 04 Mar 2028
  • 25 Nights

Interest free Monthly Payments from JUST £94pp

Cruise From:
Was £1394pp Now: £1299pp
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Holiday ID: 102188
Fly Cruise From:
£30144pp

Wonders of Patagonia & Antarctica - Cruise & Land Journey

Santiago | Torres del Paine National Park | Santiago | Torres del Paine National Park | El Calafate | Ushuaia | El Calafate | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 20 Feb 2028
  • 19 Nights
Fly Cruise From:
£30144pp
View cruise
Holiday ID: 033130
Cruise From:
Was £404pp Now: £391pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 28 May 2028
  • 6 Nights
Cruise From:
Was £404pp Now: £391pp
View cruise
Holiday ID: 100576
Cruise From:
Was £7936pp Now: £7697pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 28 Mar 2028
  • 10 Nights
Cruise From:
Was £7936pp Now: £7697pp
View cruise
Holiday ID: 099138

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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