South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2558 cruises
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Was £2609pp Now: £2499pp

16 Night Antarctica Holiday - Christmas at Sea

Buenos Aires | Punta del Este | Montevideo | Ushuaia | Gerlache Strait | Paradise Harbour | Elephant Island | Port Stanley | Puerto Madryn | Buenos Aires

  • 17 Dec 2028
  • 16 Nights

Interest free Monthly Payments from JUST £107pp

Cruise From:
Was £2609pp Now: £2499pp
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Holiday ID: 100190
Cruise From:
Was £302pp Now: £292pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 24 Nov 2028
  • 3 Nights
Cruise From:
Was £302pp Now: £292pp
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Holiday ID: 100534
Cruise From:
Was £250pp Now: £242pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 27 Nov 2028
  • 4 Nights
Cruise From:
Was £250pp Now: £242pp
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Holiday ID: 100535
Cruise From:
Was £334pp Now: £323pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 04 Feb 2029
  • 6 Nights
Cruise From:
Was £334pp Now: £323pp
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Holiday ID: 100612
Cruise From:
Was £327pp Now: £317pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 21 Jan 2029
  • 6 Nights
Cruise From:
Was £327pp Now: £317pp
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Holiday ID: 100610
Cruise From:
£364pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 07 Jan 2028
  • 3 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
£364pp
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Holiday ID: 097964
Cruise From:
Was £764pp Now: £733pp

7-Day Mexican Riviera

Los Angeles | Mazatlán | Cabo San Lucas | Los Angeles

  • 23 Apr 2028
  • 7 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £764pp Now: £733pp
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Holiday ID: 098741
Cruise From:
Was £411pp Now: £398pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 02 Apr 2029
  • 4 Nights
Cruise From:
Was £411pp Now: £398pp
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Holiday ID: 100564
Cruise From:
Was £239pp Now: £231pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 05 Jan 2029
  • 3 Nights
Cruise From:
Was £239pp Now: £231pp
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Holiday ID: 100546
Cruise From:
Was £424pp Now: £411pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 18 Mar 2029
  • 6 Nights
Cruise From:
Was £424pp Now: £411pp
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Holiday ID: 100618
Cruise From:
Was £1579pp Now: £1484pp

World-wide 18 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Ajaccio | Civitavecchia

  • 31 Mar 2027
  • 18 Nights
Cruise From:
Was £1579pp Now: £1484pp
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Holiday ID: 049697
Cruise From:
Was £5379pp Now: £5163pp

48-Day Northern Europe to South America Grand Adventure

Southampton | Hamburg | Copenhagen | Skagen | Oslo | Rotterdam | Zeebrugge | Le Havre | Southampton | Trondheim | Tromsø | Alta | Narvik | Molde | Southampton | Vigo | Lisbon | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Fortaleza | Rio de Janeiro | Montevideo | Buenos Aires

  • 04 Oct 2028
  • 48 Nights

Interest free Monthly Payments from JUST £232pp

Cruise From:
Was £5379pp Now: £5163pp
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Holiday ID: 088120
Cruise From:
Was £5615pp Now: £5446pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 13 Jan 2027
  • 8 Nights
Cruise From:
Was £5615pp Now: £5446pp
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Holiday ID: 099765
Cruise From:
Was £680pp Now: £659pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 17 Jun 2028
  • 8 Nights
Cruise From:
Was £680pp Now: £659pp
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Holiday ID: 100579
Cruise From:
Was £372pp Now: £360pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 04 Mar 2029
  • 6 Nights
Cruise From:
Was £372pp Now: £360pp
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Holiday ID: 100616
Cruise From:
Was £610pp Now: £591pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 18 Nov 2028
  • 8 Nights
Cruise From:
Was £610pp Now: £591pp
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Holiday ID: 100601
Cruise From:
Was £291pp Now: £282pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 05 Mar 2029
  • 4 Nights
Cruise From:
Was £291pp Now: £282pp
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Holiday ID: 100556
Cruise From:
Was £6328pp Now: £6138pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 05 May 2027
  • 8 Nights
Cruise From:
Was £6328pp Now: £6138pp
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Holiday ID: 099768
Cruise From:
Was £5892pp Now: £5715pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 27 Jan 2027
  • 8 Nights
Cruise From:
Was £5892pp Now: £5715pp
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Holiday ID: 099029
Cruise From:
Was £1267pp Now: £1190pp

World-wide 16 Nights From Marseille

Marseille | Valencia | Lisbon | Funchal | Salvador de Bahia | Ilheus | Buzios | Rio de Janeiro

  • 07 Nov 2027
  • 16 Nights

Interest free Monthly Payments from JUST £122pp

Cruise From:
Was £1267pp Now: £1190pp
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Holiday ID: 062679
Cruise From:
Was £487pp Now: £472pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 23 Jul 2028
  • 6 Nights
Cruise From:
Was £487pp Now: £472pp
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Holiday ID: 100584
Cruise From:
Was £8185pp Now: £7939pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 19 Feb 2027
  • 13 Nights
Cruise From:
Was £8185pp Now: £7939pp
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Holiday ID: 099085
Cruise From:
Was £475pp Now: £460pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 27 Jan 2029
  • 8 Nights
Cruise From:
Was £475pp Now: £460pp
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Holiday ID: 100611
Cruise From:
Was £269pp Now: £260pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 26 Feb 2029
  • 4 Nights
Cruise From:
Was £269pp Now: £260pp
View cruise
Holiday ID: 100554
Cruise From:
Was £336pp Now: £325pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 30 Mar 2029
  • 3 Nights
Cruise From:
Was £336pp Now: £325pp
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Holiday ID: 100563
Fly Cruise From:
Was £64390pp Now: £61814pp

Viking World Voyage III

Fort Lauderdale | Cozumel | Cartagena | Colón | Puntarenas | Cabo San Lucas | Ensenada | Los Angeles | Hilo | Honolulu | Vaitape | Papeete | Moorea | Waitangi | Auckland | Tauranga | Napier | Wellington | Sydney | Brisbane | Airlie Beach | Cairns | Thursday Island | Darwin | Rinca Island | Benoa | Semarang | Jakarta | Singapore | Port Klang | Langkawi Island | Georgetown | Phuket | Colombo | Male | Victoria | Mombasa | Zanzibar | Hell-Ville | Maputo | Richards Bay | Durban | East London | Gqeberha (ex Port Elizabeth) | Cape Town | Lüderitz | Walvis Bay | Luanda | Lagos | Accra | Takoradi | Dakar | Mindelo | Puerto de la Estaca | Agadir | Casablanca | Cádiz | Lisbon | Leixões | La Coruña | Le Havre | Dover | London (Greenwich) | Dover | Dun Laoghaire | Holyhead | Liverpool | Belfast | Ullapool | Kirkwall | Newhaven/Edinburgh | Aberdeen | Lerwick | Bergen | Eidfjord | Stavanger | Oslo | Aalborg | Copenhagen | Warnemünde | Rønne | Gdansk | Tallinn | Stockholm

  • 28 Dec 2027
  • 169 Nights
Fly Cruise From:
Was £64390pp Now: £61814pp
View cruise
Holiday ID: 061796
Cruise From:
Was £6328pp Now: £6138pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 07 Apr 2027
  • 8 Nights
Cruise From:
Was £6328pp Now: £6138pp
View cruise
Holiday ID: 099767
Cruise From:
Was £276pp Now: £267pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 19 Feb 2029
  • 4 Nights
Cruise From:
Was £276pp Now: £267pp
View cruise
Holiday ID: 100552
Cruise From:
Was £327pp Now: £317pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 10 Dec 2028
  • 6 Nights
Cruise From:
Was £327pp Now: £317pp
View cruise
Holiday ID: 100604
Cruise From:
Was £321pp Now: £311pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 09 Feb 2029
  • 3 Nights
Cruise From:
Was £321pp Now: £311pp
View cruise
Holiday ID: 100549

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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