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South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2558 cruises

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8-Day Mexican Riviera

8-Day Mexican Riviera

8-Day Mexican Riviera

Cruise From:

~~Was £490pp~~ Now: £475pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

10 Feb 2029
8 Nights
Carnival Panorama
Central America

10 Feb 2029
8 Nights

Cruise From:

~~Was £490pp~~ Now: £475pp

View cruise

Holiday ID: 100613

Chilean Fjords & the Glaciers of the Beagle Channel

Chilean Fjords & the Glaciers of the Beagle Channel

Chilean Fjords & the Glaciers of the Beagle Channel

Fly Cruise From:

£14970pp

Chilean Fjords & the Glaciers of the Beagle Channel

Buenos Aires | Ushuaia | Cape Horn | Pia Glacier | Garibaldi Glacier | Alberto de Agostini National Park | Punta Arenas | Puerto Edén | PIO X Glacier | Chilean Fjords | Castro | Puerto Montt | Niebla | Valparaiso

13 Mar 2028
13 Nights
Scenic Eclipse II
South America

13 Mar 2028
13 Nights

Fly Cruise From:

£14970pp

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Holiday ID: 082595

3-Day Baja Mexico

3-Day Baja Mexico

Long Beach, California

3-Day Baja Mexico

Long Beach, California

Cruise From:

~~Was £295pp~~ Now: £286pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

23 Mar 2029
3 Nights
Carnival Radiance
Central America

23 Mar 2029
3 Nights

Cruise From:

~~Was £295pp~~ Now: £286pp

View cruise

Holiday ID: 100561

8-Day Mexican Riviera

8-Day Mexican Riviera

Long Beach, California

8-Day Mexican Riviera

Long Beach, California

Cruise From:

~~Was £468pp~~ Now: £453pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

13 Jan 2029
8 Nights
Carnival Panorama
Central America

13 Jan 2029
8 Nights

Cruise From:

~~Was £468pp~~ Now: £453pp

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Holiday ID: 100609

World-wide 34 Nights From Barcelona

World-wide 34 Nights From Barcelona

Salvador de Bahia

World-wide 34 Nights From Barcelona

Cruise From:

~~Was £16849pp~~ Now: £15838pp

World-wide 34 Nights From Barcelona

Barcelona | Gibraltar | Casablanca | Mindelo | Salvador de Bahia | Rio de Janeiro | Buenos Aires | Puerto Madryn | Port Stanley | Ushuaia | Puerto Montt | Valparaiso

07 Jan 2027
34 Nights
MSC Magnifica
Mediterranean

07 Jan 2027
34 Nights

Cruise From:

~~Was £16849pp~~ Now: £15838pp

View cruise

Holiday ID: 062742

3-Day Baja Mexico

3-Day Baja Mexico

Long Beach, California

3-Day Baja Mexico

Long Beach, California

Cruise From:

~~Was £246pp~~ Now: £238pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

23 Feb 2029
3 Nights
Carnival Radiance
Central America

23 Feb 2029
3 Nights

Cruise From:

~~Was £246pp~~ Now: £238pp

View cruise

Holiday ID: 100553

8-Day Mexican Riviera

8-Day Mexican Riviera

8-Day Mexican Riviera

Puerto Vallarta

Cruise From:

~~Was £528pp~~ Now: £512pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

24 Feb 2029
8 Nights
Carnival Panorama
Central America

24 Feb 2029
8 Nights

Cruise From:

~~Was £528pp~~ Now: £512pp

View cruise

Holiday ID: 100615

Journeys - 14-Day Mexican Riviera

Long Beach, California

Journeys - 14-Day Mexican Riviera

Journeys - 14-Day Mexican Riviera

Long Beach, California

Cruise From:

~~Was £1150pp~~ Now: £1115pp

Journeys - 14-Day Mexican Riviera

Long Beach | Huatulco (Santa María Huatulco) | Acapulco | Manzanillo | Puerto Vallarta | Mazatlán | Cabo San Lucas | Long Beach

30 Jan 2028
14 Nights
Carnival Legend
Central America

30 Jan 2028
14 Nights

Cruise From:

~~Was £1150pp~~ Now: £1115pp

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Holiday ID: 086293

4-Day Baja Mexico

Long Beach, California

4-Day Baja Mexico

4-Day Baja Mexico

Santa Catalina Island, California

Cruise From:

~~Was £411pp~~ Now: £398pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

26 Mar 2029
4 Nights
Carnival Radiance
Central America

26 Mar 2029
4 Nights

Cruise From:

~~Was £411pp~~ Now: £398pp

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Holiday ID: 100562

World-wide 15 Nights From Southampton

World-wide 15 Nights From Southampton

World-wide 15 Nights From Southampton

Salvador de Bahia

Cruise From:

~~Was £1004pp~~ Now: £943pp

World-wide 15 Nights From Southampton

Southampton | Gijón | Vigo | Lisbon | Funchal | Maceió | Salvador de Bahia

06 Nov 2027
15 Nights
MSC Meraviglia
Mediterranean

06 Nov 2027
15 Nights

Interest free Monthly Payments from JUST £95pp

Cruise From:

~~Was £1004pp~~ Now: £943pp

View cruise

Holiday ID: 102182

3 Night Catalina & Ensenada Getaway

Santa Catalina Island, California

3 Night Catalina & Ensenada Getaway

3 Night Catalina & Ensenada Getaway

Los Angeles, California

Cruise From:

£374pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

25 Feb 2028
3 Nights
Navigator of the Seas
Central America

25 Feb 2028
3 Nights

Interest free Monthly Payments from JUST £19pp

Cruise From:

£374pp

View cruise

Holiday ID: 097960

In Darwin’s Footsteps (Eastern Route)

North Seymour Island, Galapagos

In Darwin’s Footsteps (Eastern Route)

El Edén Island, Galápagos

In Darwin’s Footsteps (Eastern Route)

South Plaza Island, Galápagos

Cruise From:

~~Was £6328pp~~ Now: £6138pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

22 Mar 2028
8 Nights
Santa Cruz II
Pacific

22 Mar 2028
8 Nights

Cruise From:

~~Was £6328pp~~ Now: £6138pp

View cruise

Holiday ID: 099049

Galápagos Islands - Nine of the Best Isles

Darwin Bay, Genovesa Island, Galápagos

Galápagos Islands - Nine of the Best Isles

Galápagos Islands - Nine of the Best Isles

Las Bachas, Santa Cruz Island, Galápagos

Cruise From:

~~Was £9099pp~~ Now: £8826pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

02 Feb 2027
10 Nights
Santa Cruz II
Pacific

02 Feb 2027
10 Nights

Cruise From:

~~Was £9099pp~~ Now: £8826pp

View cruise

Holiday ID: 099789

6-Day Mexican Riviera

6-Day Mexican Riviera

6-Day Mexican Riviera

Cruise From:

~~Was £327pp~~ Now: £317pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

12 Nov 2028
6 Nights
Carnival Panorama
Central America

12 Nov 2028
6 Nights

Cruise From:

~~Was £327pp~~ Now: £317pp

View cruise

Holiday ID: 100600

3-Day Baja Mexico

3-Day Baja Mexico

Long Beach, California

3-Day Baja Mexico

Long Beach, California

Cruise From:

~~Was £243pp~~ Now: £235pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

15 Dec 2028
3 Nights
Carnival Radiance
Central America

15 Dec 2028
3 Nights

Cruise From:

~~Was £243pp~~ Now: £235pp

View cruise

Holiday ID: 100540

3-Day Baja Mexico

Long Beach, California

3-Day Baja Mexico

3-Day Baja Mexico

Long Beach, California

Cruise From:

~~Was £269pp~~ Now: £260pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

02 Mar 2029
3 Nights
Carnival Radiance
Central America

02 Mar 2029
3 Nights

Cruise From:

~~Was £269pp~~ Now: £260pp

View cruise

Holiday ID: 100555

8-Day Mexican Riviera

8-Day Mexican Riviera

Puerto Vallarta

8-Day Mexican Riviera

Cruise From:

~~Was £565pp~~ Now: £548pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

10 Mar 2029
8 Nights
Carnival Panorama
Central America

10 Mar 2029
8 Nights

Cruise From:

~~Was £565pp~~ Now: £548pp

View cruise

Holiday ID: 100617

World-wide 85 Nights From Valparaiso

World-wide 85 Nights From Valparaiso

World-wide 85 Nights From Valparaiso

Los Angeles, California

Cruise From:

~~Was £46064pp~~ Now: £43299pp

World-wide 85 Nights From Valparaiso

Valparaiso | Hangaroa | Pitcairn Island | Papeete | Moorea | Aitutaki | Rarotonga | Bay of Islands | Auckland | Tauranga | Christchurch | Dunedin | Hobart | Sydney | Nouméa | Luganville | Pago Pago | Apia | Honolulu | Los Angeles | Cabo San Lucas | Puntarenas | Balboa (Panama City) | La Romana | Road Town | Philipsburg | Las Palmas de Gran Canaria | Ibiza | Naples | Civitavecchia | Genoa

10 Feb 2027
85 Nights
MSC Magnifica
Australasia

10 Feb 2027
85 Nights

Cruise From:

~~Was £46064pp~~ Now: £43299pp

View cruise

Holiday ID: 066651

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Santa Fé Island, Galápagos

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Puerto Baquerizo Moreno, San Cristobal Island, Galapagos

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Cruise From:

~~Was £9402pp~~ Now: £9119pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

02 Apr 2027
13 Nights
Santa Cruz II
Pacific

02 Apr 2027
13 Nights

Cruise From:

~~Was £9402pp~~ Now: £9119pp

View cruise

Holiday ID: 099086

3 Night Catalina & Ensenada Getaway

Los Angeles, California

3 Night Catalina & Ensenada Getaway

3 Night Catalina & Ensenada Getaway

Santa Catalina Island, California

Cruise From:

£432pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

24 Mar 2028
3 Nights
Navigator of the Seas
Central America

24 Mar 2028
3 Nights

Interest free Monthly Payments from JUST £22pp

Cruise From:

£432pp

View cruise

Holiday ID: 097962

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Punta Espinoza, Fernandina Island, Galápagos

Cruise From:

~~Was £10461pp~~ Now: £10147pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

14 Jan 2027
15 Nights
Santa Cruz II
Pacific

14 Jan 2027
15 Nights

Cruise From:

~~Was £10461pp~~ Now: £10147pp

View cruise

Holiday ID: 099811

8-Day Mexican Riviera

8-Day Mexican Riviera

8-Day Mexican Riviera

Cruise From:

~~Was £797pp~~ Now: £773pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

30 Dec 2028
8 Nights
Carnival Panorama
Central America

30 Dec 2028
8 Nights

Cruise From:

~~Was £797pp~~ Now: £773pp

View cruise

Holiday ID: 100607

In Darwin’s Footsteps (Eastern Route)

Santa Fé Island, Galápagos

In Darwin’s Footsteps (Eastern Route)

Punta Pitt, San Cristóbal Island, Galápagos

In Darwin’s Footsteps (Eastern Route)

Cruise From:

~~Was £5904pp~~ Now: £5726pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

10 Feb 2027
8 Nights
Santa Cruz II
Pacific

10 Feb 2027
8 Nights

Cruise From:

~~Was £5904pp~~ Now: £5726pp

View cruise

Holiday ID: 099766

3-Day Baja Mexico

Long Beach, California

3-Day Baja Mexico

Long Beach, California

3-Day Baja Mexico

Cruise From:

~~Was £291pp~~ Now: £282pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

09 Mar 2029
3 Nights
Carnival Radiance
Central America

09 Mar 2029
3 Nights

Cruise From:

~~Was £291pp~~ Now: £282pp

View cruise

Holiday ID: 100557

6-Day Mexican Riviera

6-Day Mexican Riviera

6-Day Mexican Riviera

Cruise From:

~~Was £493pp~~ Now: £478pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

11 Jun 2028
6 Nights
Carnival Panorama
Central America

11 Jun 2028
6 Nights

Cruise From:

~~Was £493pp~~ Now: £478pp

View cruise

Holiday ID: 100578

6-Day Mexican Riviera

6-Day Mexican Riviera

Long Beach, California

6-Day Mexican Riviera

Long Beach, California

Cruise From:

~~Was £339pp~~ Now: £328pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

16 Dec 2028
6 Nights
Carnival Panorama
Central America

16 Dec 2028
6 Nights

Cruise From:

~~Was £339pp~~ Now: £328pp

View cruise

Holiday ID: 100605

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Punta Pitt, San Cristóbal Island, Galápagos

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Punta Suarez, Isla Española, Galápagos

Cruise From:

~~Was £9402pp~~ Now: £9119pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

06 Aug 2027
13 Nights
Santa Cruz II
Pacific

06 Aug 2027
13 Nights

Cruise From:

~~Was £9402pp~~ Now: £9119pp

View cruise

Holiday ID: 099095

6-Day Mexican Riviera

Long Beach, California

6-Day Mexican Riviera

Long Beach, California

6-Day Mexican Riviera

Cruise From:

~~Was £372pp~~ Now: £360pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

20 Aug 2028
6 Nights
Carnival Panorama
Central America

20 Aug 2028
6 Nights

Cruise From:

~~Was £372pp~~ Now: £360pp

View cruise

Holiday ID: 100588

Brazil Intensive Cruise: Sao Paulo, Porto Belo & Rio De Janeiro

Brazil Intensive Cruise: Sao Paulo, Porto Belo & Rio De Janeiro

Brazil Intensive Cruise: Sao Paulo, Porto Belo & Rio De Janeiro

Cruise From:

~~Was £4039pp~~ Now: £3877pp

Brazil Intensive Cruise: Sao Paulo, Porto Belo & Rio De Janeiro

Buenos Aires | Montevideo | Rio Grande | Porto Belo | São Francisco do Sul | Paranaguá | São Paulo | Ilhabela | Parati | Rio de Janeiro

16 Feb 2028
12 Nights
Azamara Quest
South America

16 Feb 2028
12 Nights

Cruise From:

~~Was £4039pp~~ Now: £3877pp

View cruise

Holiday ID: 047128

3 Night Catalina & Ensenada Getaway

Los Angeles, California

3 Night Catalina & Ensenada Getaway

3 Night Catalina & Ensenada Getaway

Santa Catalina Island, California

Cruise From:

£399pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

03 Mar 2028
3 Nights
Navigator of the Seas
Central America

03 Mar 2028
3 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:

£399pp

View cruise

Holiday ID: 097963

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Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.