South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2557 cruises
Per Person
Total Price
List Grid

Range:

APPLY
Cruise From:
Was £1174pp Now: £1099pp

World-wide 14 Nights From Lisbon

Lisbon | Funchal | Salvador de Bahia | Ilheus | Buzios | Rio de Janeiro | Santos

  • 10 Nov 2027
  • 14 Nights

Interest free Monthly Payments from JUST £111pp

Cruise From:
Was £1174pp Now: £1099pp
View cruise
Holiday ID: 107883
Cruise From:
Was £2080pp Now: £1996pp

17-Day Antarctica & Patagonia

Buenos Aires | Punta Arenas | Ushuaia | Antarctic Peninsula | Port Stanley | Montevideo | Buenos Aires

  • 21 Dec 2028
  • 17 Nights

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £2080pp Now: £1996pp
View cruise
Holiday ID: 108154
Cruise From:
Was £4800pp Now: £4599pp

51-Day Ultimate Arctic to South America Passage

Southampton | Trondheim | Tromsø | Alta | Narvik | Molde | Southampton | Vigo | Lisbon | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Fortaleza | Rio de Janeiro | Montevideo | Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Cape Horn | Ushuaia | Punta Arenas | Puerto Montt | San Antonio

  • 16 Oct 2028
  • 51 Nights

Interest free Monthly Payments from JUST £202pp

Cruise From:
Was £4800pp Now: £4599pp
View cruise
Holiday ID: 108150
Cruise From:
Was £569pp Now: £540pp

South America 5 Nights From Santos

Santos | Ilha Grande | Buzios | Ilhabela | Santos

  • 21 Dec 2026
  • 5 Nights
Cruise From:
Was £569pp Now: £540pp
View cruise
Holiday ID: 063521
Cruise From:
Was £799pp Now: £751pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 01 Feb 2027
  • 7 Nights
Cruise From:
Was £799pp Now: £751pp
View cruise
Holiday ID: 079717
Cruise From:
Was £439pp Now: £417pp

South America 4 Nights From Santos

Santos | Ilha Grande | Buzios | Santos

  • 29 Nov 2026
  • 4 Nights
Cruise From:
Was £439pp Now: £417pp
View cruise
Holiday ID: 063519
Cruise From:
Was £1960pp Now: £1881pp

15-Day Cape Horn & Glaciers of Patagonia

Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Cape Horn | Ushuaia | Punta Arenas | Puerto Montt | San Antonio

  • 21 Nov 2028
  • 15 Nights

Interest free Monthly Payments from JUST £78pp

Cruise From:
Was £1960pp Now: £1881pp
View cruise
Holiday ID: 108152
Cruise From:
Was £1780pp Now: £1699pp

15-Day Cape Horn & Glaciers of Patagonia

San Antonio | Puerto Montt | Punta Arenas | Ushuaia | Cape Horn | Port Stanley | Puerto Madryn | Montevideo | Buenos Aires

  • 06 Dec 2028
  • 15 Nights

Interest free Monthly Payments from JUST £69pp

Cruise From:
Was £1780pp Now: £1699pp
View cruise
Holiday ID: 108153
Cruise From:
Was £409pp Now: £388pp

South America 4 Nights From Santos

Santos | Ilha Grande | Buzios | Santos

  • 04 Mar 2027
  • 4 Nights
Cruise From:
Was £409pp Now: £388pp
View cruise
Holiday ID: 084467
Cruise From:
£8925pp

An Extended Journey of Caribbean Charms & Amazonian Wonders

Miami | Puerto Plata | Philipsburg | Terre-de-Haut | Basseterre | San Juan (Puerto Rico) | Gustavia | Saint Pierre | Bridgetown | Port-of-Spain | Macapa | Santarém | Boca de Valeria | Manaus

  • 29 Jan 2027
  • 19 Nights
Cruise From:
£8925pp
View cruise
Holiday ID: 044375
Cruise From:
Was £1033pp Now: £971pp

World-wide 14 Nights From Lisbon

Lisbon | Funchal | Maceió | Salvador de Bahia | Ilheus | Rio de Janeiro | Santos

  • 11 Nov 2027
  • 14 Nights

Interest free Monthly Payments from JUST £96pp

Cruise From:
Was £1033pp Now: £971pp
View cruise
Holiday ID: 102184
Cruise From:
Was £1009pp Now: £948pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 27 Dec 2026
  • 7 Nights
Cruise From:
Was £1009pp Now: £948pp
View cruise
Holiday ID: 079701
CALL

64-Day Circle South America: Antarctica, Amazon & Panama Canal

Fort Lauderdale | Aruba | Cartagena | Fuerte Amador | Manta | Callao | General San Martin | Coquimbo | San Antonio | Puerto Montt | Punta Arenas | Ushuaia | Antarctic Peninsula | Port Stanley | Punta del Este | Montevideo | Buenos Aires | Rio de Janeiro | Fortaleza | Manaus | Santarém | Bridgetown | Fort Lauderdale

  • 04 Jan 2029
  • 64 Nights
CALL
View cruise
Holiday ID: 104271
Cruise From:
Was £689pp Now: £647pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 03 Jan 2027
  • 7 Nights
Cruise From:
Was £689pp Now: £647pp
View cruise
Holiday ID: 079704
Cruise From:
Was £799pp Now: £759pp

South America 6 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos

  • 01 Mar 2027
  • 6 Nights
Cruise From:
Was £799pp Now: £759pp
View cruise
Holiday ID: 094766
Cruise From:
Was £6584pp Now: £6188pp

World-wide 25 Nights From Civitavecchia

Civitavecchia | Mykonos | Marmaris | Santorini | Naples | Civitavecchia | Genoa | Marseille | Barcelona | Las Palmas de Gran Canaria | Salvador de Bahia | Ilheus | Ilha Grande | Rio de Janeiro | Santos

  • 22 Oct 2027
  • 25 Nights
Cruise From:
Was £6584pp Now: £6188pp
View cruise
Holiday ID: 062655
Cruise From:
Was £659pp Now: £619pp

Caribbean 11 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 22 Nov 2026
  • 11 Nights
Cruise From:
Was £659pp Now: £619pp
View cruise
Holiday ID: 031554
Cruise From:
Was £639pp Now: £600pp

South America 8 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires

  • 11 Dec 2026
  • 8 Nights
Cruise From:
Was £639pp Now: £600pp
View cruise
Holiday ID: 049602
Cruise From:
Was £539pp Now: £512pp

South America 4 Nights From Santos

Santos | Ilha Grande | Buzios | Santos

  • 05 Feb 2027
  • 4 Nights
Cruise From:
Was £539pp Now: £512pp
View cruise
Holiday ID: 084075
Cruise From:
Was £389pp Now: £369pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 15 Feb 2027
  • 4 Nights
Cruise From:
Was £389pp Now: £369pp
View cruise
Holiday ID: 084465
Cruise From:
Was £3749pp Now: £3599pp

Panama Canal Holiday & New Year's Cruise: Cartagena, Panama Canal & Puerto Quetzal

Miami | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Puerto Quetzal | Cabo San Lucas | San Diego

  • 18 Dec 2028
  • 16 Nights
Cruise From:
Was £3749pp Now: £3599pp
View cruise
Holiday ID: 101338
Cruise From:
Was £869pp Now: £816pp

Caribbean 11 Nights From Miami, Florida

Miami | Montego Bay | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 24 Jan 2027
  • 11 Nights
Cruise From:
Was £869pp Now: £816pp
View cruise
Holiday ID: 031560
Cruise From:
Was £399pp Now: £379pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 06 Mar 2028
  • 4 Nights

Interest free Monthly Payments from JUST £22pp

Cruise From:
Was £399pp Now: £379pp
View cruise
Holiday ID: 100228
Cruise From:
Was £619pp Now: £581pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 13 Dec 2026
  • 7 Nights
Cruise From:
Was £619pp Now: £581pp
View cruise
Holiday ID: 079695
Cruise From:
Was £429pp Now: £407pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 31 Jan 2028
  • 4 Nights

Interest free Monthly Payments from JUST £27pp

Cruise From:
Was £429pp Now: £407pp
View cruise
Holiday ID: 100218
Cruise From:
Was £929pp Now: £873pp

World-wide 14 Nights From Southampton

Southampton | Gijón | Vigo | Lisbon | Funchal | Maceió

  • 06 Nov 2027
  • 14 Nights

Interest free Monthly Payments from JUST £87pp

Cruise From:
Was £929pp Now: £873pp
View cruise
Holiday ID: 102180
Cruise From:
Was £919pp Now: £863pp

South America 9 Nights From Rio de Janeiro

Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Ilhabela | Rio de Janeiro

  • 22 Dec 2026
  • 9 Nights
Cruise From:
Was £919pp Now: £863pp
View cruise
Holiday ID: 068649
Cruise From:
Was £1019pp Now: £957pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Montevideo | Buenos Aires

  • 07 Jan 2027
  • 7 Nights
Cruise From:
Was £1019pp Now: £957pp
View cruise
Holiday ID: 079706
Cruise From:
Was £389pp Now: £369pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 25 Feb 2027
  • 4 Nights
Cruise From:
Was £389pp Now: £369pp
View cruise
Holiday ID: 084466
Fly Cruise From:
£30412pp

Wonders of Patagonia & Antarctica - Cruise & Land Journey

Santiago | Torres del Paine National Park | Santiago | Torres del Paine National Park | El Calafate | Ushuaia | El Calafate | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 10 Feb 2029
  • 19 Nights
Fly Cruise From:
£30412pp
View cruise
Holiday ID: 109186

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

Our Award Winning Service

Good Housekeeping Reader Recommended 2026
Good Housekeeping Reader Recommended 2026
Best Workplaces in Travel 2026
Best Workplaces in Travel 2026
UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
Travel Weekly Travel Agent Award 2023
Travel Weekly Travel Agent Award 2023
Best Online Travel Agency 2022
Best Online Travel Agency 2022
TTG Top 50 Ocean Travel Agency 2022
TTG Top 50 Ocean Travel Agency 2022
Best Online Agent 2021
Best Online Agent 2021
Best Company 2020
Best Company 2020
Best Online Agent 2019
Best Online Agent 2019
TTG Top 50 Travel Agency 2019
TTG Top 50 Travel Agency 2019
Explore
Blog
About Us
Careers
Contact Us
Cruise118 Brochures
Frequently Asked Questions
Privacy Policy
Terms and Conditions
Marketing Preferences
Modern Slavery Statement
Cruise Deals
Cruise Deals
Fly Cruise Deals
2026 Cruises
2027 Cruises
All Inclusive Deals
Last Minute Cruise Deals
Cheap Cruise Deals
Family Cruises
Short Cruises
Adult Only Cruises
Cruise Lines
Ambassador Cruise Line
Celebrity Cruises
Disney Cruise Line
Fred Olsen Cruise Lines
MSC Cruises
Norwegian Cruise Line
P&O Cruises
Princess Cruises
Royal Caribbean International
Virgin Voyages
All Cruise Lines
Popular Ships
Celebrity Apex
MSC Virtuosa
MSC Euribia
MSC World Europa
Arvia
Britannia
Iona
Sky Princess
Icon of The Seas
Destinations
Caribbean
Italy
Mediterranean
South America
United Kingdom
All Destinations
Cyber Essentials Plus logo ABTA member
follow us
World Travel Holdings
This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
You've added to your wishlist. To view, go to Wishlist