South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2555 cruises
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Fly Cruise From:
Was £7369pp Now: £7147pp

Rio de Janeiro to Miami

Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | Valparaiso | Coquimbo | Arica | Callao | Colón | Aruba | Miami

  • 10 Feb 2029
  • 41 Nights
Fly Cruise From:
Was £7369pp Now: £7147pp
View cruise
Holiday ID: 107954
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 30 Sep 2028
  • 7 Nights

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £559pp Now: £536pp
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Holiday ID: 108459
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 11 Nov 2028
  • 7 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £559pp Now: £536pp
View cruise
Holiday ID: 108465
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 10 Feb 2029
  • 7 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £559pp Now: £536pp
View cruise
Holiday ID: 108478
Cruise From:
Was £10412pp Now: £9787pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 01 Jul 2028
  • 7 Nights
Cruise From:
Was £10412pp Now: £9787pp
View cruise
Holiday ID: 092663
Cruise From:
£10450pp

Buenos Aires to Valparaiso

Buenos Aires | Punta del Este | Puerto Madryn | Port Stanley | Ushuaia | Cape Horn | Punta Arenas | Chilean Fjords | Laguna San Rafael National Park | Puerto Chacabuco | Castro | Puerto Montt | Valparaiso

  • 19 Feb 2029
  • 18 Nights
Cruise From:
£10450pp
View cruise
Holiday ID: 106964
Cruise From:
Was £10412pp Now: £9787pp

Valparaiso to Buenos Aires

Valparaiso | Puerto Montt | Castro | Chilean Fjords | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Buenos Aires

  • 29 Jan 2028
  • 17 Nights
Cruise From:
Was £10412pp Now: £9787pp
View cruise
Holiday ID: 031145
Cruise From:
Was £950pp Now: £912pp

11-Day Mexican Riviera

San Francisco | Manzanillo | Puerto Vallarta | Mazatlán | Cabo San Lucas | San Francisco

  • 30 Jan 2029
  • 11 Nights

Interest free Monthly Payments from JUST £34pp

Cruise From:
Was £950pp Now: £912pp
View cruise
Holiday ID: 108444
Cruise From:
Was £589pp Now: £565pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 07 Apr 2029
  • 7 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £589pp Now: £565pp
View cruise
Holiday ID: 108486
Cruise From:
Was £7862pp Now: £7390pp

Rio de Janeiro to Lisbon

Rio de Janeiro | Salvador de Bahia | Recife | Praia | Santa Cruz de Tenerife | Arrecife | Funchal | Lisbon

  • 27 Feb 2028
  • 19 Nights
Cruise From:
Was £7862pp Now: £7390pp
View cruise
Holiday ID: 031147
Cruise From:
Was £4649pp Now: £4463pp

22-Day Eastern & Southern Caribbean Holiday: Abc Islands

Fort Lauderdale | Sint Maarten | Basseterre | Fort-de-France | Roseau | Antigua | San Juan (Puerto Rico) | Half Moon Cay | Fort Lauderdale | Grand Cayman | Cartagena | Aruba | Curaçao | Half Moon Cay | Fort Lauderdale

  • 11 Dec 2027
  • 22 Nights
Cruise From:
Was £4649pp Now: £4463pp
View cruise
Holiday ID: 105290
Fly Cruise From:
Was £4179pp Now: £4053pp

Valparaiso to Miami

Valparaiso | Coquimbo | Arica | Callao | Colón | Aruba | Miami

  • 05 Mar 2029
  • 18 Nights

Interest free Monthly Payments from JUST £145pp

Fly Cruise From:
Was £4179pp Now: £4053pp
View cruise
Holiday ID: 107957
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 04 Nov 2028
  • 7 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £559pp Now: £536pp
View cruise
Holiday ID: 108464
Cruise From:
Was £7140pp Now: £6711pp

Miami to Lima

Miami | Cozumel | Puerto Limón | Colón | Manta | Callao

  • 15 Jan 2028
  • 12 Nights
Cruise From:
Was £7140pp Now: £6711pp
View cruise
Holiday ID: 050341
Cruise From:
£12820pp

San Juan to Buenos Aires

San Juan (Puerto Rico) | Gustavia | Pointe-à-Pitre | Kingstown | Scarborough | Iles du Salut | Fortaleza | Recife | Maceió | Rio de Janeiro | Santos | Montevideo | Buenos Aires

  • 27 Jan 2029
  • 23 Nights
Cruise From:
£12820pp
View cruise
Holiday ID: 106961
Fly Cruise From:
Was £5289pp Now: £5130pp

Rio de Janeiro to Valparaiso

Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | Valparaiso

  • 10 Feb 2029
  • 23 Nights

Interest free Monthly Payments from JUST £189pp

Fly Cruise From:
Was £5289pp Now: £5130pp
View cruise
Holiday ID: 107953
Cruise From:
Was £2490pp Now: £2390pp

17-Day Antarctica & Patagonia

Buenos Aires | Punta Arenas | Ushuaia | Antarctic Peninsula | Port Stanley | Montevideo | Buenos Aires

  • 24 Jan 2029
  • 17 Nights

Interest free Monthly Payments from JUST £90pp

Cruise From:
Was £2490pp Now: £2390pp
View cruise
Holiday ID: 108156
Cruise From:
Was £579pp Now: £555pp

7-Day Mexican Riviera

Los Angeles | Mazatlán | Cabo San Lucas | Los Angeles

  • 05 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £579pp Now: £555pp
View cruise
Holiday ID: 108290
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 20 Jan 2029
  • 7 Nights

Interest free Monthly Payments from JUST £21pp

Cruise From:
Was £559pp Now: £536pp
View cruise
Holiday ID: 108475
Cruise From:
Was £6035pp Now: £5672pp

Cartagena to Valparaiso

Cartagena | Panama City | Cartagena | Panama City | Manta | Callao | Valparaiso

  • 15 Jan 2028
  • 14 Nights
Cruise From:
Was £6035pp Now: £5672pp
View cruise
Holiday ID: 031144
Cruise From:
Was £11050pp Now: £10387pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 29 Jan 2028
  • 7 Nights
Cruise From:
Was £11050pp Now: £10387pp
View cruise
Holiday ID: 050298
Cruise From:
Was £10922pp Now: £10266pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 08 Apr 2028
  • 7 Nights
Cruise From:
Was £10922pp Now: £10266pp
View cruise
Holiday ID: 092651
Fly Cruise From:
Was £4049pp Now: £3927pp

Buenos Aires to Valparaiso

Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | Valparaiso

  • 17 Feb 2029
  • 16 Nights

Interest free Monthly Payments from JUST £143pp

Fly Cruise From:
Was £4049pp Now: £3927pp
View cruise
Holiday ID: 107955
Cruise From:
Was £1479pp Now: £1419pp

16-Day Panama Canal - Ocean to Ocean

San Francisco | Puerto Vallarta | Puerto Quetzal | Puntarenas | Fuerte Amador | Cartagena | Fort Lauderdale

  • 28 Aug 2028
  • 16 Nights

Interest free Monthly Payments from JUST £68pp

Cruise From:
Was £1479pp Now: £1419pp
View cruise
Holiday ID: 108433
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 18 Nov 2028
  • 7 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £559pp Now: £536pp
View cruise
Holiday ID: 108466
Cruise From:
Was £979pp Now: £939pp

7-Day Mexican Riviera Holiday

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 30 Dec 2028
  • 7 Nights

Interest free Monthly Payments from JUST £37pp

Cruise From:
Was £979pp Now: £939pp
View cruise
Holiday ID: 108472
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 03 Feb 2029
  • 7 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £559pp Now: £536pp
View cruise
Holiday ID: 108477
Cruise From:
Was £559pp Now: £536pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 17 Feb 2029
  • 7 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £559pp Now: £536pp
View cruise
Holiday ID: 108479
Cruise From:
Was £719pp Now: £675pp

Caribbean 11 Nights From Miami, Florida

Miami | Montego Bay | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 03 Jan 2027
  • 11 Nights
Cruise From:
Was £719pp Now: £675pp
View cruise
Holiday ID: 031558
Cruise From:
£6260pp

Fort Lauderdale to Los Angeles

Fort Lauderdale | Cartagena | Colón | Corinto | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Ensenada | Los Angeles

  • 04 Dec 2028
  • 15 Nights
Cruise From:
£6260pp
View cruise
Holiday ID: 106667

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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