South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2628 cruises
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Cruise From:
Was £449pp Now: £433pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 27 Feb 2027
  • 7 Nights
Cruise From:
Was £449pp Now: £433pp
View cruise
Holiday ID: 017570
Cruise From:
Was £447pp Now: £433pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 06 Aug 2028
  • 6 Nights
Cruise From:
Was £447pp Now: £433pp
View cruise
Holiday ID: 100586
Cruise From:
£434pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 13 Aug 2027
  • 3 Nights

Interest free Monthly Payments from JUST £39pp

Cruise From:
£434pp
View cruise
Holiday ID: 052598
Cruise From:
£435pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 21 Feb 2027
  • 7 Nights

Interest free Monthly Payments from JUST £194pp

Cruise From:
£435pp
View cruise
Holiday ID: 018340
Cruise From:
Was £449pp Now: £435pp

4-Day Baja Mexico

San Francisco | Ensenada | San Francisco

  • 08 Jul 2027
  • 4 Nights
Cruise From:
Was £449pp Now: £435pp
View cruise
Holiday ID: 039143
Cruise From:
Was £449pp Now: £435pp

4-Day Baja Mexico

San Francisco | Ensenada | San Francisco

  • 22 Jul 2027
  • 4 Nights
Cruise From:
Was £449pp Now: £435pp
View cruise
Holiday ID: 039145
Cruise From:
Was £452pp Now: £438pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 30 Dec 2026
  • 4 Nights
Cruise From:
Was £452pp Now: £438pp
View cruise
Holiday ID: 021804
Cruise From:
£438pp

7 Night Cabo, Vallarta & Mazatlan

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 12 Mar 2027
  • 7 Nights

Interest free Monthly Payments from JUST £123pp

Cruise From:
£438pp
View cruise
Holiday ID: 024817
Cruise From:
£438pp

4 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 09 Aug 2027
  • 4 Nights

Interest free Monthly Payments from JUST £40pp

Cruise From:
£438pp
View cruise
Holiday ID: 052524
Cruise From:
Was £453pp Now: £439pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 13 Mar 2027
  • 8 Nights
Cruise From:
Was £453pp Now: £439pp
View cruise
Holiday ID: 016060
Cruise From:
£440pp

6 Night Cabo Overnight & Catalina

Los Angeles | Santa Catalina Island | Cabo San Lucas | Los Angeles

  • 26 Mar 2027
  • 6 Nights

Interest free Monthly Payments from JUST £103pp

Cruise From:
£440pp
View cruise
Holiday ID: 024835
Cruise From:
£440pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 25 Jun 2027
  • 3 Nights

Interest free Monthly Payments from JUST £50pp

Cruise From:
£440pp
View cruise
Holiday ID: 052588
Cruise From:
Was £456pp Now: £442pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 20 Dec 2026
  • 6 Nights
Cruise From:
Was £456pp Now: £442pp
View cruise
Holiday ID: 021789
Cruise From:
£442pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 06 Aug 2027
  • 3 Nights

Interest free Monthly Payments from JUST £41pp

Cruise From:
£442pp
View cruise
Holiday ID: 052546
Cruise From:
Was £458pp Now: £444pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 15 Jan 2028
  • 8 Nights
Cruise From:
Was £458pp Now: £444pp
View cruise
Holiday ID: 039190
Cruise From:
£445pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 14 Feb 2027
  • 7 Nights

Interest free Monthly Payments from JUST £230pp

Cruise From:
£445pp
View cruise
Holiday ID: 018339
Cruise From:
£445pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

San Diego | Cabo San Lucas | Puerto Vallarta | Mazatlán | San Diego

  • 30 Jan 2027
  • 7 Nights
Cruise From:
£445pp
View cruise
Holiday ID: 018547
Cruise From:
£445pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 23 Jul 2027
  • 3 Nights

Interest free Monthly Payments from JUST £44pp

Cruise From:
£445pp
View cruise
Holiday ID: 052614
Cruise From:
Was £461pp Now: £447pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 05 Dec 2026
  • 8 Nights
Cruise From:
Was £461pp Now: £447pp
View cruise
Holiday ID: 016046
Cruise From:
£447pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 24 Mar 2028
  • 3 Nights

Interest free Monthly Payments from JUST £21pp

Cruise From:
£447pp
View cruise
Holiday ID: 097962
Cruise From:
Was £465pp Now: £448pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 02 Jan 2027
  • 7 Nights
Cruise From:
Was £465pp Now: £448pp
View cruise
Holiday ID: 017562
Cruise From:
£448pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 30 Jul 2027
  • 3 Nights

Interest free Monthly Payments from JUST £43pp

Cruise From:
£448pp
View cruise
Holiday ID: 052555
Cruise From:
Was £462pp Now: £448pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 09 Apr 2028
  • 6 Nights
Cruise From:
Was £462pp Now: £448pp
View cruise
Holiday ID: 069789
Cruise From:
Was £462pp Now: £448pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 01 Apr 2029
  • 6 Nights
Cruise From:
Was £462pp Now: £448pp
View cruise
Holiday ID: 100620
Cruise From:
Was £463pp Now: £449pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 09 Oct 2026
  • 3 Nights
Cruise From:
Was £463pp Now: £449pp
View cruise
Holiday ID: 017834
Cruise From:
£450pp

4 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 02 Aug 2027
  • 4 Nights

Interest free Monthly Payments from JUST £43pp

Cruise From:
£450pp
View cruise
Holiday ID: 052534
Cruise From:
Was £465pp Now: £451pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 09 Oct 2027
  • 8 Nights
Cruise From:
Was £465pp Now: £451pp
View cruise
Holiday ID: 039175
Cruise From:
Was £465pp Now: £451pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 23 Oct 2027
  • 8 Nights
Cruise From:
Was £465pp Now: £451pp
View cruise
Holiday ID: 039177
Cruise From:
Was £465pp Now: £451pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 04 Dec 2027
  • 8 Nights
Cruise From:
Was £465pp Now: £451pp
View cruise
Holiday ID: 039183
Cruise From:
Was £465pp Now: £451pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 29 Jan 2028
  • 8 Nights
Cruise From:
Was £465pp Now: £451pp
View cruise
Holiday ID: 039192

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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