South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2555 cruises
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Cruise From:
Was £358pp Now: £347pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 07 Jul 2028
  • 3 Nights
Cruise From:
Was £358pp Now: £347pp
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Holiday ID: 100500
Cruise From:
Was £538pp Now: £521pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 21 Dec 2028
  • 5 Nights
Cruise From:
Was £538pp Now: £521pp
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Holiday ID: 100542
Cruise From:
£355pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 10 Dec 2027
  • 3 Nights

Interest free Monthly Payments from JUST £21pp

Cruise From:
£355pp
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Holiday ID: 097965
Cruise From:
Was £8556pp Now: £8299pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 30 Mar 2027
  • 10 Nights
Cruise From:
Was £8556pp Now: £8299pp
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Holiday ID: 099793
Cruise From:
Was £358pp Now: £347pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 14 Jul 2028
  • 3 Nights
Cruise From:
Was £358pp Now: £347pp
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Holiday ID: 100502
Cruise From:
Was £484pp Now: £469pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 23 Sep 2028
  • 8 Nights
Cruise From:
Was £484pp Now: £469pp
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Holiday ID: 100593
Cruise From:
Was £334pp Now: £323pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 01 Oct 2028
  • 6 Nights
Cruise From:
Was £334pp Now: £323pp
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Holiday ID: 100594
Fly Cruise From:
Was £5899pp Now: £5722pp

Fort Lauderdale to San Antonio

Fort Lauderdale | Grand Turk Island | Bridgetown | Fortaleza | Salvador de Bahia | Buzios | Rio de Janeiro | Santos | Montevideo | Buenos Aires | Puerto Madryn | Ushuaia | Cape Horn | Punta Arenas | PIO X Glacier | Puerto Montt | Valparaiso

  • 22 Jan 2027
  • 37 Nights
Fly Cruise From:
Was £5899pp Now: £5722pp
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Holiday ID: 014877
Cruise From:
Was £12833pp Now: £12448pp

In-depth Antarctica, Falklands & South Georgia Expedition

Santiago | Punta Arenas | New Island | West Point Island | Saunders Island | Carcass Island | Port Stanley | Cape Rosa | Prion Island | Grytviken | Godthul | Stromness | Fortuna Bay | St Andrews Bay | Antarctic Sound | South Shetland Islands | Gerlache Strait | South Shetland Islands | Puerto Williams | Punta Arenas

  • 19 Feb 2027
  • 22 Nights
Cruise From:
Was £12833pp Now: £12448pp
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Holiday ID: 098937
Cruise From:
Was £10762pp Now: £10439pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 12 Aug 2027
  • 15 Nights
Cruise From:
Was £10762pp Now: £10439pp
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Holiday ID: 099171
Cruise From:
Was £7688pp Now: £7457pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 27 Apr 2027
  • 10 Nights
Cruise From:
Was £7688pp Now: £7457pp
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Holiday ID: 099795
Cruise From:
Was £532pp Now: £516pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 09 Sep 2028
  • 8 Nights
Cruise From:
Was £532pp Now: £516pp
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Holiday ID: 100591
Cruise From:
Was £8184pp Now: £7938pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 22 Jun 2027
  • 10 Nights
Cruise From:
Was £8184pp Now: £7938pp
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Holiday ID: 099125
Cruise From:
Was £7481pp Now: £7256pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 16 Mar 2027
  • 10 Nights
Cruise From:
Was £7481pp Now: £7256pp
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Holiday ID: 099792
Cruise From:
Was £394pp Now: £382pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 26 Jun 2028
  • 4 Nights
Cruise From:
Was £394pp Now: £382pp
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Holiday ID: 100497
Cruise From:
Was £273pp Now: £264pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 29 Sep 2028
  • 3 Nights
Cruise From:
Was £273pp Now: £264pp
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Holiday ID: 100524
Cruise From:
£385pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 12 Nov 2027
  • 3 Nights

Interest free Monthly Payments from JUST £27pp

Cruise From:
£385pp
View cruise
Holiday ID: 097961
Cruise From:
Was £346pp Now: £335pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 16 Jun 2028
  • 3 Nights
Cruise From:
Was £346pp Now: £335pp
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Holiday ID: 100494
Cruise From:
Was £1164pp Now: £1094pp

World-wide 21 Nights From Itajai

Itajai | Ilhabela | Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Mindelo | Las Palmas de Gran Canaria | Arrecife | Málaga | Valencia | Palma de Mallorca | Marseille

  • 05 Mar 2028
  • 21 Nights

Interest free Monthly Payments from JUST £78pp

Cruise From:
Was £1164pp Now: £1094pp
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Holiday ID: 102215
Cruise From:
£364pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 21 Jan 2028
  • 3 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
£364pp
View cruise
Holiday ID: 097957
Cruise From:
Was £8510pp Now: £8254pp

Antarctica & Falklands Expedition | Northbound (Montevideo)

Buenos Aires | Ushuaia | South Shetland Islands | Gerlache Strait | South Shetland Islands | Port Stanley | Saunders Island | Puerto Madryn | Montevideo

  • 26 Mar 2028
  • 16 Nights
Cruise From:
Was £8510pp Now: £8254pp
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Holiday ID: 098905
Cruise From:
Was £681pp Now: £660pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 15 Jul 2028
  • 8 Nights
Cruise From:
Was £681pp Now: £660pp
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Holiday ID: 100583
Cruise From:
Was £10795pp Now: £10147pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 06 Jan 2029
  • 7 Nights
Cruise From:
Was £10795pp Now: £10147pp
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Holiday ID: 092689
Fly Cruise From:
Was £9412pp Now: £7998pp

In Darwin’s Footsteps (Eastern Route)

Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 14 Jul 2027
  • 8 Nights
Fly Cruise From:
Was £9412pp Now: £7998pp
View cruise
Holiday ID: 099036
Cruise From:
Was £9402pp Now: £9119pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 09 Jul 2027
  • 13 Nights
Cruise From:
Was £9402pp Now: £9119pp
View cruise
Holiday ID: 099093
Cruise From:
Was £12166pp Now: £11799pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 16 Dec 2027
  • 15 Nights
Cruise From:
Was £12166pp Now: £11799pp
View cruise
Holiday ID: 099176
Cruise From:
Was £10762pp Now: £10439pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 27 Jan 2028
  • 15 Nights
Cruise From:
Was £10762pp Now: £10439pp
View cruise
Holiday ID: 099179
Cruise From:
Was £346pp Now: £335pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 09 Jun 2028
  • 3 Nights
Cruise From:
Was £346pp Now: £335pp
View cruise
Holiday ID: 100492
Cruise From:
Was £291pp Now: £282pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 28 Aug 2028
  • 4 Nights
Cruise From:
Was £291pp Now: £282pp
View cruise
Holiday ID: 100515
Cruise From:
Was £764pp Now: £741pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 22 Dec 2028
  • 8 Nights
Cruise From:
Was £764pp Now: £741pp
View cruise
Holiday ID: 100606

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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