South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2637 cruises
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Cruise From:
Was £659pp Now: £635pp

7-Day Mexican Riviera Holiday

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 20 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £55pp

Cruise From:
Was £659pp Now: £635pp
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Holiday ID: 049415
Cruise From:
Was £589pp Now: £571pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 20 Nov 2027
  • 8 Nights
Cruise From:
Was £589pp Now: £571pp
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Holiday ID: 039181
Cruise From:
Was £10100pp Now: £9595pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 20 Nov 2027
  • 7 Nights
Cruise From:
Was £10100pp Now: £9595pp
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Holiday ID: 050288
Cruise From:
Was £1294pp Now: £1242pp

7-Day Mexican Riviera

San Diego | Cabo San Lucas | Mazatlán | Puerto Vallarta | San Diego

  • 20 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £115pp

Cruise From:
Was £1294pp Now: £1242pp
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Holiday ID: 067767
Cruise From:
Was £683pp Now: £648pp

Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | La Paz | Mazatlán | Los Angeles

  • 20 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £62pp

Cruise From:
Was £683pp Now: £648pp
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Holiday ID: 072988
Cruise From:
Was £1999pp Now: £1929pp

15-Day Cape Horn & Glaciers of Patagonia

Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Cape Horn | Ushuaia | Punta Arenas | Puerto Montt | San Antonio

  • 21 Nov 2027
  • 15 Nights

Interest free Monthly Payments from JUST £164pp

Cruise From:
Was £1999pp Now: £1929pp
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Holiday ID: 073756
Cruise From:
Was £956pp Now: £898pp

Caribbean 11 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 21 Nov 2027
  • 11 Nights

Interest free Monthly Payments from JUST £74pp

Cruise From:
Was £956pp Now: £898pp
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Holiday ID: 058428
Cruise From:
Was £1775pp Now: £1668pp

Caribbean 21 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami | Kralendijk | Oranjestad | Willemstad | Cabo Rojo | Ocho Rios | Miami

  • 21 Nov 2027
  • 21 Nights

Interest free Monthly Payments from JUST £144pp

Cruise From:
Was £1775pp Now: £1668pp
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Holiday ID: 061490
Cruise From:
Was £8139pp Now: £7813pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 21 Nov 2027
  • 7 Nights
Cruise From:
Was £8139pp Now: £7813pp
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Holiday ID: 026826
Cruise From:
£610pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 21 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
£610pp
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Holiday ID: 062433
Cruise From:
Was £513pp Now: £497pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 21 Nov 2027
  • 6 Nights
Cruise From:
Was £513pp Now: £497pp
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Holiday ID: 069778
Cruise From:
Was £361pp Now: £350pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 22 Nov 2027
  • 4 Nights
Cruise From:
Was £361pp Now: £350pp
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Holiday ID: 069904
Cruise From:
£4915pp

A Journey of Caribbean Charm & Spectacular Natural Beauty

Miami | Willemstad | Oranjestad | Santa Marta | Cartagena | Georgetown | Miami

  • 22 Nov 2027
  • 10 Nights
Cruise From:
£4915pp
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Holiday ID: 044188
Cruise From:
£3380pp

Fort Lauderdale to Cartagena

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Colón | Cartagena

  • 22 Nov 2027
  • 10 Nights
Cruise From:
£3380pp
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Holiday ID: 032810
Cruise From:
£8150pp

Roundtrip Fort Lauderdale

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Colón | Cartagena | Oranjestad | Willemstad | Kralendijk | Pointe-à-Pitre | Marigot | San Juan (Puerto Rico) | Basseterre | Fort-de-France | Roseau | Saint John's | Gustavia | Road Town | Fort Lauderdale

  • 22 Nov 2027
  • 27 Nights
Cruise From:
£8150pp
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Holiday ID: 054538
Cruise From:
Was £14100pp Now: £13395pp

Puerto Williams to King George Island

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | King George Island

  • 22 Nov 2027
  • 9 Nights
Cruise From:
Was £14100pp Now: £13395pp
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Holiday ID: 050444
Cruise From:
Was £7688pp Now: £7457pp

Galápagos Islands - Nine of the Best Isles

Quito | Dragon Hill | Seymour | Punta Vicente Roca | Punta Espinoza | Puerto Ayora | Floreana Island | Punta Cormorant | Las Bachas | Seymour | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Darwin Bay | Seymour

  • 23 Nov 2027
  • 10 Nights
Cruise From:
Was £7688pp Now: £7457pp
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Holiday ID: 099131
Cruise From:
Was £284pp Now: £269pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 24 Nov 2027
  • 3 Nights

Interest free Monthly Payments from JUST £16pp

Cruise From:
Was £284pp Now: £269pp
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Holiday ID: 100287

Cruise & Stay

Panama Canal: Los Angeles to Miami with Los Angeles Stay

Holiday prices from:
£2379pp

Panama Canal: Los Angeles to Miami with Los Angeles Stay

Los Angeles | Cabo San Lucas | Puerto Quetzal | Puntarenas | Panama City | Cartagena | Miami

  • 25 Nov 2027
  • 20 Nights
  • Two-night 4* hotel stay in Los Angeles
  • 17-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
£2379pp
View cruise

Cruise & Stay

Mexican Riviera with Los Angeles Stay

Holiday prices from:
£1489pp

Mexican Riviera with Los Angeles Stay

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 25 Nov 2027
  • 10 Nights
  • Two-night 4* hotel stay in Los Angeles
  • Seven-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
£1489pp
View cruise
Cruise From:
Was £344pp Now: £326pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 25 Nov 2027
  • 3 Nights

Interest free Monthly Payments from JUST £21pp

Cruise From:
Was £344pp Now: £326pp
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Holiday ID: 100232
Cruise From:
Was £9402pp Now: £9119pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Cuzco | Machu Picchu | Cuzco | Quito | Mosquera Island | Seymour | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Seymour

  • 26 Nov 2027
  • 13 Nights
Cruise From:
Was £9402pp Now: £9119pp
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Holiday ID: 099100
Cruise From:
Was £297pp Now: £288pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 26 Nov 2027
  • 3 Nights
Cruise From:
Was £297pp Now: £288pp
View cruise
Holiday ID: 069905
Cruise From:
£390pp

3 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 26 Nov 2027
  • 3 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
£390pp
View cruise
Holiday ID: 097958
Fly Cruise From:
£23042pp

Highlights of Antarctica, Argentina & Brazil - Cruise & Land Journey

Rio de Janeiro | Iguazú Falls | Buenos Aires | Iguazú Falls | Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 27 Nov 2027
  • 20 Nights
Fly Cruise From:
£23042pp
View cruise
Holiday ID: 033127
Cruise From:
Was £314pp Now: £298pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 27 Nov 2027
  • 3 Nights

Interest free Monthly Payments from JUST £18pp

Cruise From:
Was £314pp Now: £298pp
View cruise
Holiday ID: 100288
Cruise From:
Was £599pp Now: £578pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 27 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £49pp

Cruise From:
Was £599pp Now: £578pp
View cruise
Holiday ID: 049416
Cruise From:
Was £11400pp Now: £10830pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 27 Nov 2027
  • 7 Nights
Cruise From:
Was £11400pp Now: £10830pp
View cruise
Holiday ID: 050289
Cruise From:
Was £1739pp Now: £1669pp

10-Day Mexican Riviera & Sea Of Cortez

San Diego | Cabo San Lucas | La Paz | Mazatlán | Puerto Vallarta | San Diego

  • 27 Nov 2027
  • 10 Nights

Interest free Monthly Payments from JUST £151pp

Cruise From:
Was £1739pp Now: £1669pp
View cruise
Holiday ID: 067768
Cruise From:
Was £1497pp Now: £1422pp

Panama Canal: Los Angeles to Miami

Los Angeles | Cabo San Lucas | Puerto Quetzal | Puntarenas | Panama City | Cartagena | Miami

  • 27 Nov 2027
  • 17 Nights

Interest free Monthly Payments from JUST £133pp

Cruise From:
Was £1497pp Now: £1422pp
View cruise
Holiday ID: 072989

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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