South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2630 cruises
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Cruise From:
Was £354pp Now: £336pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 03 Mar 2028
  • 3 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £354pp Now: £336pp
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Holiday ID: 100227
Cruise From:
Was £354pp Now: £336pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 10 Mar 2028
  • 3 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £354pp Now: £336pp
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Holiday ID: 100229
Cruise From:
Was £354pp Now: £336pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 13 Mar 2028
  • 3 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £354pp Now: £336pp
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Holiday ID: 100230
Cruise From:
Was £354pp Now: £336pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 16 Mar 2028
  • 3 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £354pp Now: £336pp
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Holiday ID: 100231
Cruise From:
Was £347pp Now: £336pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 09 Jun 2028
  • 3 Nights
Cruise From:
Was £347pp Now: £336pp
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Holiday ID: 100492
Cruise From:
Was £347pp Now: £336pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 16 Jun 2028
  • 3 Nights
Cruise From:
Was £347pp Now: £336pp
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Holiday ID: 100494
Cruise From:
£786pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 08 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
£786pp
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Holiday ID: 057577
Cruise From:
Was £695pp Now: £674pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 27 Dec 2027
  • 6 Nights
Cruise From:
Was £695pp Now: £674pp
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Holiday ID: 069782
Cruise From:
Was £969pp Now: £899pp

South America 8 Nights From Rio de Janeiro

Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Rio de Janeiro

  • 14 Dec 2026
  • 8 Nights
Cruise From:
Was £969pp Now: £899pp
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Holiday ID: 068648
Cruise From:
Was £5599pp Now: £5399pp

48-Day Northern Europe to South America Grand Adventure

Southampton | Hamburg | Copenhagen | Skagen | Oslo | Rotterdam | Zeebrugge | Le Havre | Southampton | Trondheim | Tromsø | Alta | Narvik | Molde | Southampton | Vigo | Lisbon | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Fortaleza | Rio de Janeiro | Montevideo | Buenos Aires

  • 04 Oct 2028
  • 48 Nights

Interest free Monthly Payments from JUST £225pp

Cruise From:
Was £5599pp Now: £5399pp
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Holiday ID: 088120
Cruise From:
£450pp

4 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 02 Aug 2027
  • 4 Nights

Interest free Monthly Payments from JUST £43pp

Cruise From:
£450pp
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Holiday ID: 052534
Cruise From:
£788pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Oranjestad | Colón

  • 18 Mar 2028
  • 7 Nights

Interest free Monthly Payments from JUST £44pp

Cruise From:
£788pp
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Holiday ID: 057547
Cruise From:
£788pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 25 Mar 2028
  • 7 Nights

Interest free Monthly Payments from JUST £44pp

Cruise From:
£788pp
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Holiday ID: 057595
Cruise From:
£788pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Oranjestad | Colón

  • 04 Mar 2028
  • 7 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
£788pp
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Holiday ID: 057598
Cruise From:
Was £349pp Now: £338pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 25 Jun 2027
  • 3 Nights
Cruise From:
Was £349pp Now: £338pp
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Holiday ID: 069861
Cruise From:
Was £582pp Now: £564pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 23 Dec 2027
  • 5 Nights
Cruise From:
Was £582pp Now: £564pp
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Holiday ID: 069913
Cruise From:
Was £594pp Now: £564pp

South America 5 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai

  • 09 Mar 2027
  • 5 Nights

Interest free Monthly Payments from JUST £190pp

Cruise From:
Was £594pp Now: £564pp
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Holiday ID: 084090
Cruise From:
Was £3005pp Now: £2824pp

World-wide 25 Nights From Miami, Florida

Miami | Cartagena | Colón | Huatulco (Santa María Huatulco) | Cabo San Lucas | San Diego | Los Angeles | Seattle | Ketchikan | Icy Strait Point | Juneau | Tracy Arm | Victoria | Seattle

  • 08 Apr 2027
  • 25 Nights
Cruise From:
Was £3005pp Now: £2824pp
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Holiday ID: 102780
Cruise From:
£792pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Oranjestad | Colón

  • 01 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £54pp

Cruise From:
£792pp
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Holiday ID: 057573
Cruise From:
Was £1769pp Now: £1699pp

15-Day Cape Horn & Glaciers of Patagonia

San Antonio | Puerto Montt | Punta Arenas | Ushuaia | Cape Horn | Port Stanley | Puerto Madryn | Montevideo | Buenos Aires

  • 06 Dec 2027
  • 15 Nights

Interest free Monthly Payments from JUST £138pp

Cruise From:
Was £1769pp Now: £1699pp
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Holiday ID: 073757
Cruise From:
Was £844pp Now: £793pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 06 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £56pp

Cruise From:
Was £844pp Now: £793pp
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Holiday ID: 100248
Cruise From:
Was £844pp Now: £793pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 10 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £56pp

Cruise From:
Was £844pp Now: £793pp
View cruise
Holiday ID: 100250
Cruise From:
Was £844pp Now: £793pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 13 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £55pp

Cruise From:
Was £844pp Now: £793pp
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Holiday ID: 100251
Cruise From:
Was £844pp Now: £793pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 17 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £55pp

Cruise From:
Was £844pp Now: £793pp
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Holiday ID: 100253
Cruise From:
£340pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 18 Dec 2026
  • 3 Nights
Cruise From:
£340pp
View cruise
Holiday ID: 024708
Cruise From:
Was £845pp Now: £794pp

South America 7 Nights From Salvador de Bahia

Salvador de Bahia | Maceió | Santos | Buzios | Salvador de Bahia

  • 02 Mar 2027
  • 7 Nights
Cruise From:
Was £845pp Now: £794pp
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Holiday ID: 049662
Cruise From:
£794pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 11 Mar 2028
  • 7 Nights

Interest free Monthly Payments from JUST £45pp

Cruise From:
£794pp
View cruise
Holiday ID: 057541
Cruise From:
£794pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Oranjestad | Colón

  • 15 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
£794pp
View cruise
Holiday ID: 057569

DEPARTS FROM UK

Cruise From:
Was £8799pp Now: £8535pp

Epic South America Journey

Southampton | Las Palmas de Gran Canaria | Sao Vicente Island | Recife | Salvador de Bahia | Rio de Janeiro | Santos | Montevideo | Falkland Islands | Punta Arenas | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Fuerte Amador | Cartagena | Aruba | Curaçao | Saint George's | Bridgetown | Castries | Saint John's | Sint Maarten | Santa Cruz de Tenerife | Southampton

  • 03 Jan 2028
  • 75 Nights
Cruise From:
Was £8799pp Now: £8535pp
View cruise
Holiday ID: 049345

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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