South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2633 cruises
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Cruise From:
Was £1161pp Now: £1120pp

11-Day Mexican Riviera Holiday

San Francisco | Manzanillo | Puerto Vallarta | Mazatlán | Cabo San Lucas | San Francisco

  • 15 Dec 2026
  • 11 Nights
Cruise From:
Was £1161pp Now: £1120pp
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Holiday ID: 017538
Cruise From:
Was £1192pp Now: £1120pp

Caribbean 11 Nights From Miami, Florida

Miami | Montego Bay | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 03 Jan 2027
  • 11 Nights
Cruise From:
Was £1192pp Now: £1120pp
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Holiday ID: 031558
Cruise From:
Was £316pp Now: £306pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 18 Feb 2028
  • 3 Nights
Cruise From:
Was £316pp Now: £306pp
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Holiday ID: 069928
Cruise From:
Was £316pp Now: £306pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 11 Feb 2028
  • 3 Nights
Cruise From:
Was £316pp Now: £306pp
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Holiday ID: 090954
Cruise From:
Was £324pp Now: £307pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 30 Mar 2028
  • 3 Nights

Interest free Monthly Payments from JUST £14pp

Cruise From:
Was £324pp Now: £307pp
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Holiday ID: 100281
Cruise From:
Was £324pp Now: £307pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 09 Apr 2028
  • 3 Nights

Interest free Monthly Payments from JUST £14pp

Cruise From:
Was £324pp Now: £307pp
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Holiday ID: 100284
Cruise From:
Was £324pp Now: £307pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 16 Apr 2028
  • 3 Nights

Interest free Monthly Payments from JUST £14pp

Cruise From:
Was £324pp Now: £307pp
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Holiday ID: 100286
Cruise From:
Was £1150pp Now: £1127pp

Panama Canal: Mexico, Costa Rica & Belize

Miami | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 09 Dec 2027
  • 11 Nights

Interest free Monthly Payments from JUST £91pp

Cruise From:
Was £1150pp Now: £1127pp
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Holiday ID: 062557
Cruise From:
Was £1169pp Now: £1128pp

11-Day Mexican Riviera

San Francisco | Manzanillo | Puerto Vallarta | Cabo San Lucas | San Francisco

  • 27 Oct 2027
  • 11 Nights

Interest free Monthly Payments from JUST £104pp

Cruise From:
Was £1169pp Now: £1128pp
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Holiday ID: 049392
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Maceió

Maceió | Santos | Buzios | Salvador de Bahia | Maceió

  • 09 Dec 2026
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 049627
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 12 Dec 2026
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 049628
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 20 Dec 2026
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 079698
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 21 Dec 2026
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 079699
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 03 Jan 2027
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 079704
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 04 Jan 2027
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 079705
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Santos

Santos | Camboriú | Montevideo | Buenos Aires | Santos

  • 10 Jan 2027
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 079707
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Paranaguá

Paranaguá | Itajai | Ilhabela | Rio de Janeiro | Buzios | Ilha Grande | Paranaguá

  • 02 Jan 2027
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 088415
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai | Ilhabela | Rio de Janeiro

  • 05 Jan 2027
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 088416
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Paranaguá

Paranaguá | Itajai | Ilhabela | Rio de Janeiro | Buzios | Ilha Grande | Paranaguá

  • 09 Jan 2027
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 088417
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai | Ilhabela | Rio de Janeiro

  • 12 Jan 2027
  • 7 Nights
Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 088418
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 20 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
Was £764pp Now: £718pp
View cruise
Holiday ID: 100254
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 24 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 100256
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Montevideo | Buenos Aires

  • 27 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 100257
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Camboriú

Camboriú | Montevideo | Buenos Aires | Santos | Camboriú

  • 31 Jan 2028
  • 7 Nights

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 100259
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 03 Feb 2028
  • 7 Nights

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £764pp Now: £718pp
View cruise
Holiday ID: 100260
Cruise From:
Was £764pp Now: £718pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 07 Feb 2028
  • 7 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £764pp Now: £718pp
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Holiday ID: 100262
Cruise From:
Was £318pp Now: £308pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 11 Aug 2028
  • 3 Nights
Cruise From:
Was £318pp Now: £308pp
View cruise
Holiday ID: 100510
Cruise From:
£720pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Oranjestad | Colón

  • 18 Dec 2027
  • 7 Nights

Interest free Monthly Payments from JUST £50pp

Cruise From:
£720pp
View cruise
Holiday ID: 057553
Cruise From:
£1543pp

15 Night Panama Canal Eastward Cruise

San Diego | Puerto Vallarta | Puerto Quetzal | Puntarenas | Cartagena | Georgetown | Tampa

  • 07 Oct 2027
  • 15 Nights

Interest free Monthly Payments from JUST £151pp

Cruise From:
£1543pp
View cruise
Holiday ID: 069304
Cruise From:
£310pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 26 Mar 2027
  • 3 Nights

Interest free Monthly Payments from JUST £57pp

Cruise From:
£310pp
View cruise
Holiday ID: 024729

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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