South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2630 cruises
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Cruise From:
Was £714pp Now: £671pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 12 Feb 2028
  • 7 Nights

Interest free Monthly Payments from JUST £42pp

Cruise From:
Was £714pp Now: £671pp
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Holiday ID: 100381
Cruise From:
Was £714pp Now: £671pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 19 Feb 2028
  • 7 Nights

Interest free Monthly Payments from JUST £42pp

Cruise From:
Was £714pp Now: £671pp
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Holiday ID: 100384
Cruise From:
Was £714pp Now: £671pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 26 Feb 2028
  • 7 Nights

Interest free Monthly Payments from JUST £41pp

Cruise From:
Was £714pp Now: £671pp
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Holiday ID: 100387
Cruise From:
Was £714pp Now: £671pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 04 Mar 2028
  • 7 Nights

Interest free Monthly Payments from JUST £40pp

Cruise From:
Was £714pp Now: £671pp
View cruise
Holiday ID: 100390
Cruise From:
Was £714pp Now: £671pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 11 Mar 2028
  • 7 Nights

Interest free Monthly Payments from JUST £40pp

Cruise From:
Was £714pp Now: £671pp
View cruise
Holiday ID: 100393
Cruise From:
Was £714pp Now: £671pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 18 Mar 2028
  • 7 Nights

Interest free Monthly Payments from JUST £39pp

Cruise From:
Was £714pp Now: £671pp
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Holiday ID: 100396

DEPARTS FROM UK

Cruise From:
Was £1499pp Now: £1439pp

Christmas & New Year Voyage to Spain & Portugal

Tilbury | Gijón | Lisbon | Portimão | Cádiz | Málaga | Cartagena | Gibraltar | Vigo | Tilbury

  • 21 Dec 2026
  • 15 Nights
Cruise From:
Was £1499pp Now: £1439pp
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Holiday ID: 023852
Cruise From:
£288pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 23 Apr 2027
  • 3 Nights

Interest free Monthly Payments from JUST £37pp

Cruise From:
£288pp
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Holiday ID: 052565
Cruise From:
Was £792pp Now: £768pp

8-Day Mexican Riviera

Long Beach | Cabo San Lucas | Mazatlán | Puerto Vallarta | Long Beach

  • 19 Dec 2027
  • 8 Nights
Cruise From:
Was £792pp Now: £768pp
View cruise
Holiday ID: 069781
Cruise From:
Was £297pp Now: £288pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 20 Aug 2027
  • 3 Nights
Cruise From:
Was £297pp Now: £288pp
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Holiday ID: 069877
Cruise From:
Was £297pp Now: £288pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 26 Nov 2027
  • 3 Nights
Cruise From:
Was £297pp Now: £288pp
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Holiday ID: 069905
Cruise From:
Was £699pp Now: £674pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 21 Nov 2026
  • 7 Nights
Cruise From:
Was £699pp Now: £674pp
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Holiday ID: 017556
Cruise From:
Was £699pp Now: £674pp

7-Day Mexican Riviera Holiday

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 22 Dec 2027
  • 7 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £699pp Now: £674pp
View cruise
Holiday ID: 049420
Cruise From:
Was £699pp Now: £674pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 12 Feb 2028
  • 7 Nights

Interest free Monthly Payments from JUST £45pp

Cruise From:
Was £699pp Now: £674pp
View cruise
Holiday ID: 049427
Cruise From:
£289pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 11 Dec 2026
  • 3 Nights
Cruise From:
£289pp
View cruise
Holiday ID: 024699

DEPARTS FROM UK

Cruise From:
Was £1509pp Now: £1448pp

Christmas Sun Escape to Spain & Portugal

Tilbury | Vigo | Cádiz | Motril | Cartagena | Alicante | Almería | Gibraltar | Leixões | Tilbury

  • 21 Dec 2028
  • 15 Nights

Interest free Monthly Payments from JUST £55pp

Cruise From:
Was £1509pp Now: £1448pp
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Holiday ID: 080228
Cruise From:
Was £925pp Now: £869pp

South America 9 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Rio de Janeiro

  • 06 Feb 2028
  • 9 Nights

Interest free Monthly Payments from JUST £58pp

Cruise From:
Was £925pp Now: £869pp
View cruise
Holiday ID: 100342
Cruise From:
£290pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 16 Apr 2027
  • 3 Nights

Interest free Monthly Payments from JUST £40pp

Cruise From:
£290pp
View cruise
Holiday ID: 024685
Cruise From:
£387pp

4 Night Catalina & Ensenada Getaway

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 24 May 2027
  • 4 Nights

Interest free Monthly Payments from JUST £51pp

Cruise From:
£387pp
View cruise
Holiday ID: 052561
Cruise From:
Was £798pp Now: £774pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 30 Dec 2028
  • 8 Nights
Cruise From:
Was £798pp Now: £774pp
View cruise
Holiday ID: 100607
Cruise From:
Was £409pp Now: £388pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 26 Nov 2026
  • 4 Nights
Cruise From:
Was £409pp Now: £388pp
View cruise
Holiday ID: 049572
Cruise From:
£291pp

3 Night Ensenada Cruise

San Diego | Ensenada | San Diego

  • 22 Apr 2027
  • 3 Nights

Interest free Monthly Payments from JUST £39pp

Cruise From:
£291pp
View cruise
Holiday ID: 050076
Cruise From:
Was £401pp Now: £388pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 05 Jul 2027
  • 4 Nights
Cruise From:
Was £401pp Now: £388pp
View cruise
Holiday ID: 069864
Cruise From:
Was £401pp Now: £388pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 12 Jul 2027
  • 4 Nights
Cruise From:
Was £401pp Now: £388pp
View cruise
Holiday ID: 069866
Cruise From:
Was £401pp Now: £388pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 19 Jul 2027
  • 4 Nights
Cruise From:
Was £401pp Now: £388pp
View cruise
Holiday ID: 069868
Cruise From:
Was £409pp Now: £388pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 25 Feb 2028
  • 4 Nights

Interest free Monthly Payments from JUST £21pp

Cruise From:
Was £409pp Now: £388pp
View cruise
Holiday ID: 100225
Cruise From:
Was £724pp Now: £680pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 15 Feb 2027
  • 7 Nights
Cruise From:
Was £724pp Now: £680pp
View cruise
Holiday ID: 079724
Cruise From:
Was £724pp Now: £680pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 28 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £724pp Now: £680pp
View cruise
Holiday ID: 100233
Cruise From:
Was £724pp Now: £680pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 29 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £724pp Now: £680pp
View cruise
Holiday ID: 100234
Cruise From:
Was £724pp Now: £680pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 02 Dec 2027
  • 7 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £724pp Now: £680pp
View cruise
Holiday ID: 100235

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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