South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2629 cruises
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DEPARTS FROM UK

Cruise From:
Was £4049pp Now: £3887pp

Tropical Treasures: Mayan Ruins & Island Adventures

Tilbury | Ponta Delgada | Saint John's | Philipsburg | Samaná | Santo Domingo | Ocho Rios | Cozumel | Belize City | Puerto Limón | Colón | Santa Marta | Oranjestad | Castries | Praia da Vitória | Horta | Tilbury

  • 06 Jan 2028
  • 44 Nights
Cruise From:
Was £4049pp Now: £3887pp
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Holiday ID: 037131
Cruise From:
Was £754pp Now: £708pp

South America 8 Nights From Rio de Janeiro

Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Rio de Janeiro

  • 27 Mar 2028
  • 8 Nights

Interest free Monthly Payments from JUST £41pp

Cruise From:
Was £754pp Now: £708pp
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Holiday ID: 100354
Cruise From:
Was £365pp Now: £354pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 05 Jun 2028
  • 4 Nights
Cruise From:
Was £365pp Now: £354pp
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Holiday ID: 100491
Cruise From:
Was £1990pp Now: £1950pp

Panama Canal: Mexico & Costa Rica

New York | Puerto Plata | Cartagena | Colón | Puerto Caldera | Puerto Quetzal | Acapulco | Puerto Vallarta | Cabo San Lucas | San Francisco | Victoria | Seattle

  • 09 Apr 2027
  • 22 Nights
Cruise From:
Was £1990pp Now: £1950pp
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Holiday ID: 038626
Cruise From:
Was £275pp Now: £266pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 27 Aug 2027
  • 3 Nights
Cruise From:
Was £275pp Now: £266pp
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Holiday ID: 069879
Cruise From:
Was £275pp Now: £266pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 08 Oct 2027
  • 3 Nights
Cruise From:
Was £275pp Now: £266pp
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Holiday ID: 069891
Cruise From:
Was £367pp Now: £355pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 14 Jun 2027
  • 4 Nights
Cruise From:
Was £367pp Now: £355pp
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Holiday ID: 069858
Cruise From:
Was £366pp Now: £355pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 20 Nov 2028
  • 4 Nights
Cruise From:
Was £366pp Now: £355pp
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Holiday ID: 100533
Cruise From:
£622pp

7 Night Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | Mazatlán | Ensenada | Los Angeles

  • 14 Apr 2028
  • 7 Nights

Interest free Monthly Payments from JUST £31pp

Cruise From:
£622pp
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Holiday ID: 052452
Cruise From:
Was £1609pp Now: £1512pp

World-wide 17 Nights From Rio de Janeiro

Rio de Janeiro | Salvador de Bahia | Maceió | Santa Cruz de Tenerife | Casablanca | Málaga | Alicante | Barcelona | Naples

  • 15 Mar 2027
  • 17 Nights
Cruise From:
Was £1609pp Now: £1512pp
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Holiday ID: 049566
Cruise From:
£356pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 22 Mar 2027
  • 4 Nights

Interest free Monthly Payments from JUST £77pp

Cruise From:
£356pp
View cruise
Holiday ID: 024705
Cruise From:
Was £759pp Now: £713pp

South America 8 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires

  • 05 Dec 2027
  • 8 Nights

Interest free Monthly Payments from JUST £54pp

Cruise From:
Was £759pp Now: £713pp
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Holiday ID: 100327
Cruise From:
Was £759pp Now: £713pp

South America 8 Nights From Rio de Janeiro

Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Rio de Janeiro

  • 08 Dec 2027
  • 8 Nights

Interest free Monthly Payments from JUST £54pp

Cruise From:
Was £759pp Now: £713pp
View cruise
Holiday ID: 100328
Cruise From:
Was £759pp Now: £713pp

South America 8 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires

  • 13 Dec 2027
  • 8 Nights

Interest free Monthly Payments from JUST £53pp

Cruise From:
Was £759pp Now: £713pp
View cruise
Holiday ID: 100329
Cruise From:
Was £759pp Now: £713pp

South America 8 Nights From Rio de Janeiro

Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Rio de Janeiro

  • 16 Dec 2027
  • 8 Nights

Interest free Monthly Payments from JUST £53pp

Cruise From:
Was £759pp Now: £713pp
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Holiday ID: 100330
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Itajai

Itajai | Ilhabela | Rio de Janeiro | Ilha Grande | Buzios | Paranaguá | Itajai

  • 24 Jan 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
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Holiday ID: 067844
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Paranaguá

Paranaguá | Itajai | Ilhabela | Rio de Janeiro | Buzios | Ilha Grande | Paranaguá

  • 16 Jan 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
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Holiday ID: 067979
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai | Ilhabela | Rio de Janeiro

  • 19 Jan 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
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Holiday ID: 067980
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Paranaguá

Paranaguá | Itajai | Ilhabela | Rio de Janeiro | Ilha Grande | Buzios | Paranaguá

  • 23 Jan 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
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Holiday ID: 067981
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Rio de Janeiro

Rio de Janeiro | Ilha Grande | Buzios | Paranaguá | Itajai | Ilhabela | Rio de Janeiro

  • 26 Jan 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
View cruise
Holiday ID: 067982
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Paranaguá

Paranaguá | Itajai | Ilhabela | Rio de Janeiro | Buzios | Ilha Grande | Paranaguá

  • 30 Jan 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
View cruise
Holiday ID: 067983
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai | Ilhabela | Rio de Janeiro

  • 02 Feb 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
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Holiday ID: 067984
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 31 Jan 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
View cruise
Holiday ID: 079716
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 01 Feb 2027
  • 7 Nights
Cruise From:
Was £664pp Now: £624pp
View cruise
Holiday ID: 079717
Cruise From:
Was £277pp Now: £268pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 18 Dec 2028
  • 3 Nights
Cruise From:
Was £277pp Now: £268pp
View cruise
Holiday ID: 100541
Cruise From:
£358pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 29 Mar 2027
  • 4 Nights

Interest free Monthly Payments from JUST £72pp

Cruise From:
£358pp
View cruise
Holiday ID: 024720
Cruise From:
Was £284pp Now: £269pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 24 Nov 2027
  • 3 Nights

Interest free Monthly Payments from JUST £16pp

Cruise From:
Was £284pp Now: £269pp
View cruise
Holiday ID: 100287
Cruise From:
Was £284pp Now: £269pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 30 Nov 2027
  • 3 Nights

Interest free Monthly Payments from JUST £16pp

Cruise From:
Was £284pp Now: £269pp
View cruise
Holiday ID: 100289
Cruise From:
Was £284pp Now: £269pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 03 Dec 2027
  • 3 Nights

Interest free Monthly Payments from JUST £15pp

Cruise From:
Was £284pp Now: £269pp
View cruise
Holiday ID: 100290
Cruise From:
Was £371pp Now: £359pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 24 Dec 2026
  • 4 Nights
Cruise From:
Was £371pp Now: £359pp
View cruise
Holiday ID: 017854

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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