South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2628 cruises
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Cruise From:
Was £555pp Now: £538pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 25 Mar 2028
  • 8 Nights
Cruise From:
Was £555pp Now: £538pp
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Holiday ID: 039200
Cruise From:
Was £209pp Now: £202pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 11 Dec 2026
  • 3 Nights
Cruise From:
Was £209pp Now: £202pp
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Holiday ID: 017853
Cruise From:
Was £1649pp Now: £1550pp

World-wide 23 Nights From Santos

Santos | Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Santa Cruz de Tenerife | Tangier | Barcelona | La Goulette | Palermo | Naples | Livorno | Marseille

  • 25 Mar 2028
  • 23 Nights

Interest free Monthly Payments from JUST £97pp

Cruise From:
Was £1649pp Now: £1550pp
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Holiday ID: 102225
Cruise From:
Was £1221pp Now: £1147pp

World-wide 17 Nights From Naples

Naples | Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro

  • 29 Oct 2026
  • 17 Nights
Cruise From:
Was £1221pp Now: £1147pp
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Holiday ID: 049535
Cruise From:
£473pp

7 Nt Cabo Overnight Catalina & Ensenada

Los Angeles | Santa Catalina Island | Cabo San Lucas | Ensenada | Los Angeles

  • 26 Feb 2027
  • 7 Nights

Interest free Monthly Payments from JUST £171pp

Cruise From:
£473pp
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Holiday ID: 024688
Cruise From:
Was £1224pp Now: £1150pp

World-wide 17 Nights From Genoa

Genoa | Marseille | Barcelona | Las Palmas de Gran Canaria | Salvador de Bahia | Ilheus | Ilha Grande | Rio de Janeiro | Santos

  • 30 Oct 2027
  • 17 Nights

Interest free Monthly Payments from JUST £103pp

Cruise From:
Was £1224pp Now: £1150pp
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Holiday ID: 071934
Cruise From:
Was £1297pp Now: £1219pp

World-wide 18 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Ajaccio | Civitavecchia

  • 31 Mar 2027
  • 18 Nights
Cruise From:
Was £1297pp Now: £1219pp
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Holiday ID: 049697
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 08 Feb 2027
  • 4 Nights

Interest free Monthly Payments from JUST £93pp

Cruise From:
£271pp
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Holiday ID: 024718
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 07 Feb 2027
  • 4 Nights

Interest free Monthly Payments from JUST £95pp

Cruise From:
£271pp
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Holiday ID: 024779
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 24 Jan 2027
  • 4 Nights
Cruise From:
£271pp
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Holiday ID: 024791
Cruise From:
£271pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 14 Feb 2027
  • 4 Nights

Interest free Monthly Payments from JUST £81pp

Cruise From:
£271pp
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Holiday ID: 024795
Cruise From:
Was £559pp Now: £542pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 12 Aug 2028
  • 8 Nights
Cruise From:
Was £559pp Now: £542pp
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Holiday ID: 100587
Cruise From:
£475pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 07 Mar 2027
  • 7 Nights

Interest free Monthly Payments from JUST £172pp

Cruise From:
£475pp
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Holiday ID: 018342
Cruise From:
£475pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

San Diego | Cabo San Lucas | Mazatlán | Puerto Vallarta | San Diego

  • 06 Feb 2027
  • 7 Nights
Cruise From:
£475pp
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Holiday ID: 018548
Cruise From:
Was £1084pp Now: £1018pp

World-wide 15 Nights From Marseille

Marseille | Barcelona | Las Palmas de Gran Canaria | Salvador de Bahia | Ilheus | Ilha Grande | Rio de Janeiro

  • 31 Oct 2027
  • 15 Nights

Interest free Monthly Payments from JUST £90pp

Cruise From:
Was £1084pp Now: £1018pp
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Holiday ID: 062662
Cruise From:
Was £281pp Now: £272pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 29 Apr 2027
  • 4 Nights
Cruise From:
Was £281pp Now: £272pp
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Holiday ID: 069845
Cruise From:
Was £1159pp Now: £1089pp

World-wide 16 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Santa Cruz de Tenerife | Tangier | Barcelona

  • 26 Mar 2028
  • 16 Nights

Interest free Monthly Payments from JUST £66pp

Cruise From:
Was £1159pp Now: £1089pp
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Holiday ID: 102227
Cruise From:
Was £1449pp Now: £1362pp

World-wide 20 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Salvador de Bahia | Maceió | Santa Cruz de Tenerife | Tangier | Barcelona | La Goulette | Palermo | Naples

  • 26 Mar 2028
  • 20 Nights

Interest free Monthly Payments from JUST £84pp

Cruise From:
Was £1449pp Now: £1362pp
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Holiday ID: 102230

DEPARTS FROM UK

Cruise From:
Was £3199pp Now: £3071pp

Caribbean Sunsets & South American Secrets

Tilbury | Ponta Delgada | Bridgetown | Willemstad | Oranjestad | Santa Marta | Cartagena | Colón | Puerto Limón | Belize City | Georgetown | Montego Bay | Santo Domingo | Saint John's | Praia da Vitória | Tilbury

  • 03 Jan 2027
  • 45 Nights
Cruise From:
Was £3199pp Now: £3071pp
View cruise
Holiday ID: 023812
Cruise From:
Was £1394pp Now: £1299pp

World-wide 19 Nights From Naples

Naples | Civitavecchia | Genoa | Marseille | Barcelona | Las Palmas de Gran Canaria | Salvador de Bahia | Ilheus | Ilha Grande | Rio de Janeiro | Santos

  • 28 Oct 2027
  • 19 Nights

Interest free Monthly Payments from JUST £118pp

Cruise From:
Was £1394pp Now: £1299pp
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Holiday ID: 062657
Cruise From:
Was £710pp Now: £685pp

10-Day Baja Peninsula & Sea of Cortez Holiday

Los Angeles | Cabo San Lucas | La Paz | Guaymas | Puerto Vallarta | Los Angeles

  • 30 Dec 2026
  • 10 Nights
Cruise From:
Was £710pp Now: £685pp
View cruise
Holiday ID: 017525
Cruise From:
Was £565pp Now: £548pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 10 Mar 2029
  • 8 Nights
Cruise From:
Was £565pp Now: £548pp
View cruise
Holiday ID: 100617
Cruise From:
Was £424pp Now: £411pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 18 Mar 2029
  • 6 Nights
Cruise From:
Was £424pp Now: £411pp
View cruise
Holiday ID: 100618
Cruise From:
Was £1678pp Now: £1577pp

World-wide 23 Nights From Rio de Janeiro

Rio de Janeiro | Maceió | Mindelo | Funchal | Lisbon | Casablanca | Málaga | Palma de Mallorca | Barcelona | Marseille | Genoa | Naples

  • 08 Mar 2027
  • 23 Nights
Cruise From:
Was £1678pp Now: £1577pp
View cruise
Holiday ID: 080878
Cruise From:
£480pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Puerto Vallarta | Mazatlán | Cabo San Lucas | Los Angeles

  • 14 Nov 2027
  • 7 Nights

Interest free Monthly Payments from JUST £37pp

Cruise From:
£480pp
View cruise
Holiday ID: 062432
Cruise From:
Was £1153pp Now: £1099pp

16 Nt Spain To Argentina Transatlantic

Barcelona | Tangier | Salvador de Bahia | Rio de Janeiro | Montevideo | Buenos Aires

  • 19 Nov 2026
  • 16 Nights
Cruise From:
Was £1153pp Now: £1099pp
View cruise
Holiday ID: 017779
Cruise From:
Was £499pp Now: £481pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 02 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £49pp

Cruise From:
Was £499pp Now: £481pp
View cruise
Holiday ID: 049408
Cruise From:
Was £499pp Now: £481pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 09 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
Was £499pp Now: £481pp
View cruise
Holiday ID: 049409
Cruise From:
Was £499pp Now: £481pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 16 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £499pp Now: £481pp
View cruise
Holiday ID: 049410
Cruise From:
Was £499pp Now: £481pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 23 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £45pp

Cruise From:
Was £499pp Now: £481pp
View cruise
Holiday ID: 049411

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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