P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 420 cruises
Per Person
Total Price

Sails from the UK

Cruise From:
Was £974pp Now: £944pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 09 Oct 2027
  • 14 Nights

Interest free Monthly Payments from JUST £120pp

Cruise From:
Was £974pp Now: £944pp
Holiday ID: 032634

Sails from the UK

Cruise From:
Was £974pp Now: £944pp

Southampton | Skagen | Copenhagen | Oslo | Zeebrugge | Southampton

  • 26 May 2027
  • 7 Nights
Cruise From:
Was £974pp Now: £944pp
Holiday ID: 032639

Sails from the UK

Cruise From:
Was £979pp Now: £949pp

Southampton | Lisbon | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | La Coruña | Southampton

  • 30 Nov 2028
  • 15 Nights

Interest free Monthly Payments from JUST £42pp

Cruise From:
Was £979pp Now: £949pp
Holiday ID: 107262
Fly Cruise From:
Was £984pp Now: £954pp

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 14 Nights

Interest free Monthly Payments from JUST £114pp

Fly Cruise From:
Was £984pp Now: £954pp
Holiday ID: 049282

Sails from the UK

Cruise From:
Was £1014pp Now: £983pp

Southampton | Haugesund | Olden | Molde | Bodø | Ålesund | Skjolden | Stavanger | Southampton

  • 11 Oct 2027
  • 14 Nights

Interest free Monthly Payments from JUST £124pp

Cruise From:
Was £1014pp Now: £983pp
Holiday ID: 032649

Sails from the UK

Cruise From:
Was £1019pp Now: £988pp

Southampton | Funchal | Agadir | Casablanca | Tangier | Lisbon | La Coruña | Southampton

  • 27 Nov 2026
  • 14 Nights
Cruise From:
Was £1019pp Now: £988pp
Holiday ID: 015120

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Vigo | Málaga | Alicante | La Seyne-sur-Mer | Barcelona | Cádiz | Southampton

  • 18 Jul 2027
  • 14 Nights

Interest free Monthly Payments from JUST £204pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 032608

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Lanzarote | Cádiz | Lisbon | Southampton

  • 19 Mar 2028
  • 14 Nights

Interest free Monthly Payments from JUST £73pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 049224

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Agadir | Casablanca | Tangier | Málaga | Cádiz | Southampton

  • 09 Dec 2027
  • 12 Nights

Interest free Monthly Payments from JUST £99pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 049269

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 26 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 081149

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 01 Apr 2028
  • 14 Nights

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 081206

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 22 Apr 2028
  • 14 Nights

Interest free Monthly Payments from JUST £67pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 081208

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 14 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 081225

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 28 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £1024pp Now: £993pp
Holiday ID: 081226
Fly Cruise From:
Was £1034pp Now: £999pp

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 15 Nights

Interest free Monthly Payments from JUST £120pp

Fly Cruise From:
Was £1034pp Now: £999pp
Holiday ID: 049283

Sails from the UK

Cruise From:
Was £1044pp Now: £1012pp

Southampton | Haugesund | Olden | Ålesund | Stavanger | Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 11 Apr 2027
  • 14 Nights
Cruise From:
Was £1044pp Now: £1012pp
Holiday ID: 046137

Sails from the UK

Cruise From:
Was £1049pp Now: £1017pp

Southampton | Funchal | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Casablanca | Tangier | Cádiz | La Coruña | Southampton

  • 12 Feb 2027
  • 14 Nights
Cruise From:
Was £1049pp Now: £1017pp
Holiday ID: 015116

Sails from the UK

Cruise From:
Was £1054pp Now: £1022pp

Southampton | Haugesund | Olden | Åndalsnes | Oslo | Copenhagen | Aarhus | Hamburg | Southampton

  • 27 Aug 2027
  • 14 Nights

Interest free Monthly Payments from JUST £162pp

Cruise From:
Was £1054pp Now: £1022pp
Holiday ID: 032555

Sails from the UK

Cruise From:
Was £1054pp Now: £1022pp

Southampton | Cádiz | Ibiza | Cagliari | Palma de Mallorca | Cartagena | Gibraltar | Southampton

  • 30 Sep 2028
  • 14 Nights

Interest free Monthly Payments from JUST £49pp

Cruise From:
Was £1054pp Now: £1022pp
Holiday ID: 081224

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Cádiz | Málaga | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 09 May 2027
  • 14 Nights
Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 032602

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Cádiz | Málaga | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 06 Jun 2027
  • 14 Nights
Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 032605

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 26 Jun 2027
  • 14 Nights
Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 032624

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Lisbon | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Funchal | Southampton

  • 02 Apr 2028
  • 12 Nights

Interest free Monthly Payments from JUST £73pp

Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 081087

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Cádiz | Barcelona | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 13 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £49pp

Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 081107

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Getxo | Vigo | Lisbon | Leixões | Saint Peter Port | Southampton

  • 22 Jul 2028
  • 10 Nights

Interest free Monthly Payments from JUST £57pp

Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 081217

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 16 Sep 2028
  • 14 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 081223

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Southampton | Skjolden | Harstad | Kristiansund | Olden | Eidfjord | Zeebrugge | Southampton

  • 24 May 2028
  • 12 Nights

Interest free Monthly Payments from JUST £65pp

Cruise From:
Was £1074pp Now: £1041pp
Holiday ID: 081230

Sails from the UK

Cruise From:
Was £1084pp Now: £1051pp

Southampton | La Coruña | Vigo | Málaga | Alicante | La Seyne-sur-Mer | Barcelona | Cádiz | Southampton

  • 20 Jun 2027
  • 14 Nights
Cruise From:
Was £1084pp Now: £1051pp
Holiday ID: 032606

Sails from the UK

Cruise From:
Was £1099pp Now: £1066pp

Southampton | Hamburg | Zeebrugge | Southampton

  • 29 Dec 2026
  • 5 Nights
Cruise From:
Was £1099pp Now: £1066pp
Holiday ID: 015123
Fly Cruise From:
Was £1099pp Now: £1066pp

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown

  • 28 Oct 2028
  • 13 Nights

Interest free Monthly Payments from JUST £49pp

Fly Cruise From:
Was £1099pp Now: £1066pp
Holiday ID: 107144

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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