P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

P&O Cruises P&O Cruise Deals  P&O Cruises 2026 P&O Cruises 2027 P&O Cruises 2028

Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 420 cruises
Per Person
Total Price

Sails from the UK

Cruise From:
Was £274pp Now: £265pp

Southampton | Zeebrugge | Southampton

  • 22 Jan 2028
  • 3 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £274pp Now: £265pp
Holiday ID: 049334

Sails from the UK

Cruise From:
Was £294pp Now: £285pp

Southampton | Le Havre | Southampton

  • 20 Dec 2027
  • 4 Nights

Interest free Monthly Payments from JUST £28pp

Cruise From:
Was £294pp Now: £285pp
Holiday ID: 049330

Sails from the UK

Cruise From:
Was £304pp Now: £294pp

Southampton | Zeebrugge | Southampton

  • 15 Mar 2028
  • 3 Nights

Interest free Monthly Payments from JUST £22pp

Cruise From:
Was £304pp Now: £294pp
Holiday ID: 049338

Sails from the UK

Cruise From:
Was £304pp Now: £294pp

Southampton | Zeebrugge | Southampton

  • 05 May 2028
  • 3 Nights

Interest free Monthly Payments from JUST £19pp

Cruise From:
Was £304pp Now: £294pp
Holiday ID: 098875

Sails from the UK

Cruise From:
Was £324pp Now: £314pp

Southampton | Cherbourg | Le Havre | Southampton

  • 08 Feb 2028
  • 4 Nights

Interest free Monthly Payments from JUST £26pp

Cruise From:
Was £324pp Now: £314pp
Holiday ID: 098871

Sails from the UK

Cruise From:
Was £334pp Now: £323pp

Southampton | Zeebrugge | Southampton

  • 02 May 2028
  • 3 Nights

Interest free Monthly Payments from JUST £22pp

Cruise From:
Was £334pp Now: £323pp
Holiday ID: 081228

Sails from the UK

Cruise From:
Was £344pp Now: £333pp

Southampton | Rotterdam | Southampton

  • 13 Sep 2027
  • 4 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
Was £344pp Now: £333pp
Holiday ID: 032648

Sails from the UK

Cruise From:
Was £349pp Now: £338pp

Southampton | Amsterdam | Southampton

  • 08 Feb 2027
  • 4 Nights
Cruise From:
Was £349pp Now: £338pp
Holiday ID: 015115

Sails from the UK

Cruise From:
Was £349pp Now: £338pp

Southampton | Le Havre | Zeebrugge | Southampton

  • 19 Apr 2027
  • 4 Nights

Interest free Monthly Payments from JUST £220pp

Cruise From:
Was £349pp Now: £338pp
Holiday ID: 074827

Sails from the UK

Cruise From:
Was £354pp Now: £343pp

Southampton | Zeebrugge | Le Havre | Southampton

  • 16 Dec 2027
  • 4 Nights

Interest free Monthly Payments from JUST £34pp

Cruise From:
Was £354pp Now: £343pp
Holiday ID: 049329

Sails from the UK

Cruise From:
Was £354pp Now: £343pp

Southampton | Zeebrugge | Southampton

  • 16 Apr 2027
  • 3 Nights

Interest free Monthly Payments from JUST £240pp

Cruise From:
Was £354pp Now: £343pp
Holiday ID: 074826

Sails from the UK

Cruise From:
Was £354pp Now: £343pp

Southampton | Rotterdam | Southampton

  • 26 Feb 2028
  • 4 Nights

Interest free Monthly Payments from JUST £27pp

Cruise From:
Was £354pp Now: £343pp
Holiday ID: 098874

Sails from the UK

Cruise From:
Was £359pp Now: £348pp

Southampton | Zeebrugge | Le Havre | Southampton

  • 29 Nov 2026
  • 4 Nights
Cruise From:
Was £359pp Now: £348pp
Holiday ID: 015113

Sails from the UK

Cruise From:
Was £364pp Now: £353pp

Southampton | Rotterdam | Southampton

  • 21 Jun 2027
  • 4 Nights

Interest free Monthly Payments from JUST £92pp

Cruise From:
Was £364pp Now: £353pp
Holiday ID: 032640

Sails from the UK

Cruise From:
Was £374pp Now: £362pp

Southampton | Rotterdam | Southampton

  • 21 Apr 2027
  • 4 Nights

Interest free Monthly Payments from JUST £225pp

Cruise From:
Was £374pp Now: £362pp
Holiday ID: 032637

Sails from the UK

Cruise From:
Was £374pp Now: £362pp

Southampton | Cherbourg | Le Havre | Zeebrugge | Southampton

  • 22 Feb 2028
  • 5 Nights

Interest free Monthly Payments from JUST £29pp

Cruise From:
Was £374pp Now: £362pp
Holiday ID: 049222

Sails from the UK

Cruise From:
Was £374pp Now: £362pp

Southampton | Zeebrugge | Southampton

  • 25 Aug 2028
  • 3 Nights

Interest free Monthly Payments from JUST £19pp

Cruise From:
Was £374pp Now: £362pp
Holiday ID: 081100

Sails from the UK

Cruise From:
Was £379pp Now: £367pp

Southampton | Zeebrugge | Southampton

  • 30 Nov 2026
  • 3 Nights
Cruise From:
Was £379pp Now: £367pp
Holiday ID: 015066

Sails from the UK

Cruise From:
Was £379pp Now: £367pp

Southampton | Rotterdam | Southampton

  • 14 Nov 2028
  • 4 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £379pp Now: £367pp
Holiday ID: 107138

Sails from the UK

Cruise From:
Was £399pp Now: £387pp

Southampton | Zeebrugge | Rotterdam | Cherbourg | Southampton

  • 08 Feb 2027
  • 5 Nights
Cruise From:
Was £399pp Now: £387pp
Holiday ID: 015060

Sails from the UK

Cruise From:
Was £399pp Now: £387pp

Southampton | Amsterdam | Southampton

  • 14 Dec 2028
  • 4 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £399pp Now: £387pp
Holiday ID: 107248

Sails from the UK

Cruise From:
Was £399pp Now: £387pp

Southampton | Le Havre | Cherbourg | Southampton

  • 18 Dec 2028
  • 4 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £399pp Now: £387pp
Holiday ID: 107249

Sails from the UK

Cruise From:
Was £399pp Now: £387pp

Southampton | Rotterdam | Southampton

  • 26 Jan 2029
  • 4 Nights

Interest free Monthly Payments from JUST £16pp

Cruise From:
Was £399pp Now: £387pp
Holiday ID: 107254

Sails from the UK

Cruise From:
Was £404pp Now: £391pp

Southampton | Hamburg | Zeebrugge | Southampton

  • 12 Nov 2027
  • 5 Nights

Interest free Monthly Payments from JUST £43pp

Cruise From:
Was £404pp Now: £391pp
Holiday ID: 049215

Sails from the UK

Cruise From:
Was £404pp Now: £391pp

Southampton | Le Havre | Southampton

  • 27 Jun 2028
  • 4 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £404pp Now: £391pp
Holiday ID: 081214

Sails from the UK

Cruise From:
Was £414pp Now: £401pp

Southampton | Zeebrugge | Southampton

  • 31 Mar 2027
  • 3 Nights
Cruise From:
Was £414pp Now: £401pp
Holiday ID: 032614

Sails from the UK

Cruise From:
Was £424pp Now: £411pp

Southampton | Zeebrugge | Rotterdam | Hamburg | Southampton

  • 19 Feb 2028
  • 7 Nights

Interest free Monthly Payments from JUST £33pp

Cruise From:
Was £424pp Now: £411pp
Holiday ID: 098873

Sails from the UK

Cruise From:
Was £429pp Now: £416pp

Southampton | Rotterdam | Southampton

  • 06 Feb 2029
  • 4 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £429pp Now: £416pp
Holiday ID: 107256

Sails from the UK

Cruise From:
Was £434pp Now: £420pp

Southampton | Hamburg | Zeebrugge | Cherbourg | Southampton

  • 21 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £434pp Now: £420pp
Holiday ID: 081136

Sails from the UK

Cruise From:
Was £449pp Now: £435pp

Southampton | Rotterdam | Southampton

  • 11 Dec 2026
  • 4 Nights
Cruise From:
Was £449pp Now: £435pp
Holiday ID: 015121

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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