Mediterranean Cruises from Southampton

Cruises From Southampton > Mediterranean Cruises from Southampton

Discover amazing Mediterranean cruises from all of our amazing cruise lines. Explore our selection of Mediterranean cruises from Southampton to avoid the need and hassle of airports. Mediterranean cruises from Southampton provide an unforgettable experience that allows you to explore the beautiful sights and cities of our European cruise destinations. Book using our cruise deals to find great cruises to the Mediterranean for a great price.

Cruises From Southampton  2025 Cruises From Southampton European Cruises From Southampton

Italy Cruises From Southampton Mediterranean Cruises Mediterranean Cruise Deals

Looking for the best cruise deals on our Mediterranean cruises from Southampton? Book your cruise deal online with Cruise118 and guarantee the best possible price on all Mediterranean cruises from Southampton.

Showing 30 out of 483 cruises
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Sails from the UK

Cruise From:
£1033pp

9 Night Spanish Flair Cruise

Southampton | Vigo | Lisbon | Cádiz | La Coruña | Bilbao | Southampton

  • 30 Aug 2027
  • 9 Nights

Interest free Monthly Payments from JUST £136pp

Cruise From:
£1033pp
View cruise
Holiday ID: 075973
Cruise From:
Was £1084pp Now: £1040pp

15-Day Western Europe Passage

Southampton | Cherbourg | Vigo | Funchal | Santa Cruz de Tenerife | Kings Wharf | Fort Lauderdale

  • 28 Oct 2028
  • 15 Nights

Interest free Monthly Payments from JUST £45pp

Cruise From:
Was £1084pp Now: £1040pp
View cruise
Holiday ID: 088387

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Mediterranean - Spain France And Italy

Southampton | Cádiz | Málaga | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 09 May 2027
  • 14 Nights
Cruise From:
Was £1074pp Now: £1041pp
View cruise
Holiday ID: 032602

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Mediterranean - Spain France And Italy

Southampton | Cádiz | Málaga | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 06 Jun 2027
  • 14 Nights
Cruise From:
Was £1074pp Now: £1041pp
View cruise
Holiday ID: 032605

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 26 Jun 2027
  • 14 Nights
Cruise From:
Was £1074pp Now: £1041pp
View cruise
Holiday ID: 032624

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Portugal And Canary Islands

Southampton | Lisbon | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Funchal | Southampton

  • 02 Apr 2028
  • 12 Nights

Interest free Monthly Payments from JUST £73pp

Cruise From:
Was £1074pp Now: £1041pp
View cruise
Holiday ID: 081087

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Mediterranean - Spain France And Italy

Southampton | Cádiz | Barcelona | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 13 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £49pp

Cruise From:
Was £1074pp Now: £1041pp
View cruise
Holiday ID: 081107

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Spain And Portugal

Southampton | Getxo | Vigo | Lisbon | Leixões | Saint Peter Port | Southampton

  • 22 Jul 2028
  • 10 Nights

Interest free Monthly Payments from JUST £57pp

Cruise From:
Was £1074pp Now: £1041pp
View cruise
Holiday ID: 081217

Sails from the UK

Cruise From:
Was £1074pp Now: £1041pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 16 Sep 2028
  • 14 Nights

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £1074pp Now: £1041pp
View cruise
Holiday ID: 081223

Sails from the UK

Cruise From:
Was £1084pp Now: £1051pp

Mediterranean - Spain And France

Southampton | La Coruña | Vigo | Málaga | Alicante | La Seyne-sur-Mer | Barcelona | Cádiz | Southampton

  • 20 Jun 2027
  • 14 Nights
Cruise From:
Was £1084pp Now: £1051pp
View cruise
Holiday ID: 032606

Sails from the UK

Cruise From:
Was £1099pp Now: £1066pp

Canary Island Celebration

Southampton | Lisbon | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Southampton

  • 16 Dec 2026
  • 12 Nights
Cruise From:
Was £1099pp Now: £1066pp
View cruise
Holiday ID: 013749
Fly Cruise From:
Was £1099pp Now: £1066pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown

  • 28 Oct 2028
  • 13 Nights

Interest free Monthly Payments from JUST £49pp

Fly Cruise From:
Was £1099pp Now: £1066pp
View cruise
Holiday ID: 107144

Sails from the UK

Cruise From:
Was £1109pp Now: £1075pp

Spain and Portugal

Southampton | Praia da Vitória | Ponta Delgada | Funchal | Lisbon | Vigo | Southampton

  • 31 Oct 2027
  • 12 Nights

Interest free Monthly Payments from JUST £117pp

Cruise From:
Was £1109pp Now: £1075pp
View cruise
Holiday ID: 035169

Sails from the UK

Cruise From:
Was £1124pp Now: £1090pp

Spain France And Norwegian Fjords

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton | Haugesund | Ålesund | Skjolden | Stavanger | Southampton

  • 02 Apr 2027
  • 14 Nights
Cruise From:
Was £1124pp Now: £1090pp
View cruise
Holiday ID: 074823

Sails from the UK

Cruise From:
Was £1124pp Now: £1090pp

Mediterranean - Spain France And Italy

Southampton | Cádiz | Barcelona | La Seyne-sur-Mer | La Spezia | Civitavecchia | Alicante | Southampton

  • 02 Sep 2028
  • 14 Nights

Interest free Monthly Payments from JUST £55pp

Cruise From:
Was £1124pp Now: £1090pp
View cruise
Holiday ID: 081222

Sails from the UK

Cruise From:
Was £1129pp Now: £1095pp

Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Lanzarote | Lisbon | Southampton

  • 16 Nov 2027
  • 12 Nights

Interest free Monthly Payments from JUST £112pp

Cruise From:
Was £1129pp Now: £1095pp
View cruise
Holiday ID: 035171

Sails from the UK

Cruise From:
Was £1129pp Now: £1095pp

Spain

Southampton | Funchal | Santa Cruz de Tenerife | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 17 Feb 2029
  • 14 Nights

Interest free Monthly Payments from JUST £43pp

Cruise From:
Was £1129pp Now: £1095pp
View cruise
Holiday ID: 107257

Sails from the UK

Cruise From:
Was £1144pp Now: £1099pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Ferrol | Southampton

  • 15 Oct 2027
  • 14 Nights

Interest free Monthly Payments from JUST £136pp

Cruise From:
Was £1144pp Now: £1099pp
View cruise
Holiday ID: 032560

Sails from the UK

Cruise From:
Was £1144pp Now: £1099pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 17 Jul 2027
  • 14 Nights

Interest free Monthly Payments from JUST £228pp

Cruise From:
Was £1144pp Now: £1099pp
View cruise
Holiday ID: 032626

Sails from the UK

Cruise From:
Was £1149pp Now: £1114pp

Canary Islands

Southampton | Cádiz | Funchal | Santa Cruz de Tenerife | Santa Cruz de La Palma | Lanzarote | Southampton

  • 21 Nov 2027
  • 12 Nights

Interest free Monthly Payments from JUST £112pp

Cruise From:
Was £1149pp Now: £1114pp
View cruise
Holiday ID: 035334
Fly Cruise From:
Was £1149pp Now: £1114pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown

  • 28 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £51pp

Fly Cruise From:
Was £1149pp Now: £1114pp
View cruise
Holiday ID: 107145
Cruise From:
Was £1189pp Now: £1117pp

World-wide 18 Nights From Southampton

Southampton | Gijón | Vigo | Lisbon | Funchal | Maceió | Salvador de Bahia | Ilheus | Rio de Janeiro

  • 06 Nov 2027
  • 18 Nights

Interest free Monthly Payments from JUST £114pp

Cruise From:
Was £1189pp Now: £1117pp
View cruise
Holiday ID: 102181

Sails from the UK

Cruise From:
Was £1154pp Now: £1119pp

Spain Portugal And Canary Islands

Southampton | Lanzarote | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Funchal | Cádiz | Lisbon | Southampton

  • 30 Sep 2028
  • 14 Nights

Interest free Monthly Payments from JUST £54pp

Cruise From:
Was £1154pp Now: £1119pp
View cruise
Holiday ID: 081134

Sails from the UK

Cruise From:
Was £1149pp Now: £1126pp

A Taste of Spain & Portugal

Southampton | Vigo | Cádiz | Lisbon | Leixões | Southampton

  • 14 Mar 2027
  • 11 Nights
Cruise From:
Was £1149pp Now: £1126pp
View cruise
Holiday ID: 048514

Sails from the UK

Cruise From:
Was £1174pp Now: £1138pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 01 Jul 2028
  • 14 Nights

Interest free Monthly Payments from JUST £65pp

Cruise From:
Was £1174pp Now: £1138pp
View cruise
Holiday ID: 081215

Sails from the UK

Cruise From:
Was £1179pp Now: £1143pp

Spain and Portugal

Southampton | Lisbon | Alicante | Barcelona | Málaga | Cádiz | Southampton

  • 03 Dec 2027
  • 12 Nights

Interest free Monthly Payments from JUST £110pp

Cruise From:
Was £1179pp Now: £1143pp
View cruise
Holiday ID: 035335
Fly Cruise From:
Was £1179pp Now: £1143pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 20 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £53pp

Fly Cruise From:
Was £1179pp Now: £1143pp
View cruise
Holiday ID: 107202

Sails from the UK

Cruise From:
Was £1184pp Now: £1148pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 13 May 2028
  • 14 Nights

Interest free Monthly Payments from JUST £73pp

Cruise From:
Was £1184pp Now: £1148pp
View cruise
Holiday ID: 081210

Sails from the UK

Cruise From:
Was £1199pp Now: £1163pp

Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Lanzarote | Lisbon | Southampton

  • 29 Oct 2028
  • 12 Nights

Interest free Monthly Payments from JUST £51pp

Cruise From:
Was £1199pp Now: £1163pp
View cruise
Holiday ID: 084296

Sails from the UK

Cruise From:
Was £1204pp Now: £1167pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 03 Jun 2028
  • 14 Nights

Interest free Monthly Payments from JUST £71pp

Cruise From:
Was £1204pp Now: £1167pp
View cruise
Holiday ID: 081212

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Go On An All Inclusive Mediterranean Cruise from Southampton

At Cruise118, our cruise holidays are made all the better when you decide to go on an all inclusive cruise to the Mediterranean. With cruises from Southampton, you can save money by not needing to arrange flights. These savings can be put towards going all inclusive.

Find Mediterranean Cruises from Southampton Deals

Explore our cruise deals and save money on your Mediterranean cruise from Southampton. With our family cruise deals, you can go on a family holiday and find amazing deals, or book a last minute cruise deal and get the ultimate cheap cruise from Cruise118.

Book Your Mediterranean Cruise from Southampton

Ensure you book your place on a Mediterranean cruise from Southampton and use our cruise deals for 2025 to make your summer cruise holiday your best one yet. Or plan ahead and get your 2026 cruise booked and enjoy early booking discounts.

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