Mediterranean Cruises from Southampton

Cruises From Southampton > Mediterranean Cruises from Southampton

Discover amazing Mediterranean cruises from all of our amazing cruise lines. Explore our selection of Mediterranean cruises from Southampton to avoid the need and hassle of airports. Mediterranean cruises from Southampton provide an unforgettable experience that allows you to explore the beautiful sights and cities of our European cruise destinations. Book using our cruise deals to find great cruises to the Mediterranean for a great price.

Cruises From Southampton  2025 Cruises From Southampton European Cruises From Southampton

Italy Cruises From Southampton Mediterranean Cruises Mediterranean Cruise Deals

Looking for the best cruise deals on our Mediterranean cruises from Southampton? Book your cruise deal online with Cruise118 and guarantee the best possible price on all Mediterranean cruises from Southampton.

Showing 30 out of 483 cruises
Per Person
Total Price
List Grid

Range:

APPLY

Sails from the UK

Cruise From:
Was £974pp Now: £944pp

Spain And Portugal

Southampton | La Coruña | Vigo | Lisbon | Leixões | Saint Peter Port | Southampton

  • 29 May 2027
  • 10 Nights
Cruise From:
Was £974pp Now: £944pp
View cruise
Holiday ID: 032620

Sails from the UK

Cruise From:
Was £974pp Now: £944pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 09 Oct 2027
  • 14 Nights

Interest free Monthly Payments from JUST £120pp

Cruise From:
Was £974pp Now: £944pp
View cruise
Holiday ID: 032634

Sails from the UK

Cruise From:
Was £1029pp Now: £946pp

France, Spain & Portugal

Southampton | Brest | Lisbon | Vigo | Cherbourg | Southampton

  • 10 Jul 2027
  • 7 Nights

Interest free Monthly Payments from JUST £168pp

Cruise From:
Was £1029pp Now: £946pp
View cruise
Holiday ID: 048994

Sails from the UK

Cruise From:
Was £979pp Now: £949pp

Spain and Portugal

Southampton | Lisbon | Vigo | Southampton

  • 03 Sep 2027
  • 7 Nights

Interest free Monthly Payments from JUST £136pp

Cruise From:
Was £979pp Now: £949pp
View cruise
Holiday ID: 035209

Sails from the UK

Cruise From:
Was £979pp Now: £949pp

Spain

Southampton | Lisbon | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | La Coruña | Southampton

  • 30 Nov 2028
  • 15 Nights

Interest free Monthly Payments from JUST £42pp

Cruise From:
Was £979pp Now: £949pp
View cruise
Holiday ID: 107262
Fly Cruise From:
Was £984pp Now: £954pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 14 Nights

Interest free Monthly Payments from JUST £114pp

Fly Cruise From:
Was £984pp Now: £954pp
View cruise
Holiday ID: 049282

Sails from the UK

Cruise From:
Was £1039pp Now: £955pp

France, Spain & Portugal

Southampton | La Coruña | Gibraltar | Casablanca | Cádiz | Southampton

  • 14 Oct 2027
  • 9 Nights

Interest free Monthly Payments from JUST £105pp

Cruise From:
Was £1039pp Now: £955pp
View cruise
Holiday ID: 049001

Sails from the UK

Cruise From:
Was £999pp Now: £969pp

PRICE DROP! Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Lanzarote | Lisbon | Southampton

  • 04 Dec 2026
  • 12 Nights
Cruise From:
Was £999pp Now: £969pp
View cruise
Holiday ID: 013748

Sails from the UK

Cruise From:
£972pp

8 Night Spain & Portugal Cruise

Southampton | Vigo | Lisbon | La Coruña | Bilbao | Southampton

  • 09 Aug 2027
  • 8 Nights

Interest free Monthly Payments from JUST £142pp

Cruise From:
£972pp
View cruise
Holiday ID: 075912

Sails from the UK

Cruise From:
£976pp

9 Night Spanish Flair Cruise

Southampton | Vigo | Lisbon | Cádiz | La Coruña | Bilbao | Southampton

  • 19 Sep 2028
  • 9 Nights

Interest free Monthly Payments from JUST £44pp

Cruise From:
£976pp
View cruise
Holiday ID: 106792

Sails from the UK

Cruise From:
Was £1349pp Now: £979pp

TravelZoo Offer! Southern Spain & Portugal Winter Warmth

Southampton | Vigo | Gibraltar | Málaga | Cádiz | Leixões | Southampton

  • 20 Jan 2027
  • 13 Nights
Cruise From:
Was £1349pp Now: £979pp
View cruise
Holiday ID: 048510

Sails from the UK

Cruise From:
Was £1019pp Now: £988pp

Spain Portugal and Morocco

Southampton | Funchal | Agadir | Casablanca | Tangier | Lisbon | La Coruña | Southampton

  • 27 Nov 2026
  • 14 Nights
Cruise From:
Was £1019pp Now: £988pp
View cruise
Holiday ID: 015120

Sails from the UK

Cruise From:
Was £1074pp Now: £988pp

France & Spain

Southampton | Gijón | La Rochelle | Bilbao | Cherbourg | Southampton

  • 29 May 2027
  • 7 Nights

Interest free Monthly Payments from JUST £244pp

Cruise From:
Was £1074pp Now: £988pp
View cruise
Holiday ID: 048990

Sails from the UK

Cruise From:
£988pp

8 Night Spain & Portugal Cruise

Southampton | Vigo | Lisbon | La Coruña | Bilbao | Southampton

  • 06 Aug 2028
  • 8 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
£988pp
View cruise
Holiday ID: 106791

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Mediterranean - Spain France And Italy

Southampton | Vigo | Málaga | Alicante | La Seyne-sur-Mer | Barcelona | Cádiz | Southampton

  • 18 Jul 2027
  • 14 Nights

Interest free Monthly Payments from JUST £204pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 032608

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Lanzarote | Cádiz | Lisbon | Southampton

  • 19 Mar 2028
  • 14 Nights

Interest free Monthly Payments from JUST £73pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 049224

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Spain And Morocco

Southampton | Agadir | Casablanca | Tangier | Málaga | Cádiz | Southampton

  • 09 Dec 2027
  • 12 Nights

Interest free Monthly Payments from JUST £99pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 049269

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 26 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 081149

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 01 Apr 2028
  • 14 Nights

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 081206

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 22 Apr 2028
  • 14 Nights

Interest free Monthly Payments from JUST £67pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 081208

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 14 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 081225

Sails from the UK

Cruise From:
Was £1024pp Now: £993pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 28 Oct 2028
  • 14 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £1024pp Now: £993pp
View cruise
Holiday ID: 081226
Fly Cruise From:
Was £1034pp Now: £999pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 15 Nights

Interest free Monthly Payments from JUST £120pp

Fly Cruise From:
Was £1034pp Now: £999pp
View cruise
Holiday ID: 049283

Sails from the UK

Cruise From:
Was £1044pp Now: £1012pp

Norwegian Fjords, Spain & France from Southampton

Southampton | Haugesund | Olden | Ålesund | Stavanger | Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 11 Apr 2027
  • 14 Nights
Cruise From:
Was £1044pp Now: £1012pp
View cruise
Holiday ID: 046137

Sails from the UK

Cruise From:
Was £1049pp Now: £1017pp

Spain Portugal Canary Islands and Morocco

Southampton | Funchal | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Casablanca | Tangier | Cádiz | La Coruña | Southampton

  • 12 Feb 2027
  • 14 Nights
Cruise From:
Was £1049pp Now: £1017pp
View cruise
Holiday ID: 015116

Sails from the UK

Cruise From:
£1018pp

8 Night Spain & Portugal Cruise

Southampton | Bilbao | Lisbon | Vigo | La Coruña | Southampton

  • 26 Jun 2027
  • 8 Nights

Interest free Monthly Payments from JUST £199pp

Cruise From:
£1018pp
View cruise
Holiday ID: 075972

Sails from the UK

Cruise From:
Was £1054pp Now: £1022pp

Mediterranean Islands

Southampton | Cádiz | Ibiza | Cagliari | Palma de Mallorca | Cartagena | Gibraltar | Southampton

  • 30 Sep 2028
  • 14 Nights

Interest free Monthly Payments from JUST £49pp

Cruise From:
Was £1054pp Now: £1022pp
View cruise
Holiday ID: 081224

Sails from the UK

Cruise From:
£1025pp

9 Night Spanish Flair Cruise

Southampton | Vigo | Lisbon | Cádiz | La Coruña | Bilbao | Southampton

  • 19 Jun 2028
  • 9 Nights

Interest free Monthly Payments from JUST £55pp

Cruise From:
£1025pp
View cruise
Holiday ID: 106784

Sails from the UK

Cruise From:
£1025pp

9 Night Spanish Flair Cruise

Southampton | Bilbao | Cádiz | Lisbon | Vigo | La Coruña | Southampton

  • 28 Aug 2028
  • 9 Nights

Interest free Monthly Payments from JUST £48pp

Cruise From:
£1025pp
View cruise
Holiday ID: 106794

Sails from the UK

Cruise From:
£1027pp

9 Night Spain & Portugal Cruise

Southampton | Vigo | Lisbon | Cádiz | La Coruña | Bilbao | Southampton

  • 10 Sep 2028
  • 9 Nights

Interest free Monthly Payments from JUST £47pp

Cruise From:
£1027pp
View cruise
Holiday ID: 106785

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Go On An All Inclusive Mediterranean Cruise from Southampton

At Cruise118, our cruise holidays are made all the better when you decide to go on an all inclusive cruise to the Mediterranean. With cruises from Southampton, you can save money by not needing to arrange flights. These savings can be put towards going all inclusive.

Find Mediterranean Cruises from Southampton Deals

Explore our cruise deals and save money on your Mediterranean cruise from Southampton. With our family cruise deals, you can go on a family holiday and find amazing deals, or book a last minute cruise deal and get the ultimate cheap cruise from Cruise118.

Book Your Mediterranean Cruise from Southampton

Ensure you book your place on a Mediterranean cruise from Southampton and use our cruise deals for 2025 to make your summer cruise holiday your best one yet. Or plan ahead and get your 2026 cruise booked and enjoy early booking discounts.

Our Award Winning Service

Good Housekeeping Reader Recommended 2026
Good Housekeeping Reader Recommended 2026
Best Workplaces in Travel 2026
Best Workplaces in Travel 2026
UK Cruise Awards 2026 Partnership Achievement Award
UK Cruise Awards 2026 Partnership Achievement Award
Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
Travel Weekly Travel Agent Award 2023
Travel Weekly Travel Agent Award 2023
Best Online Travel Agency 2022
Best Online Travel Agency 2022
TTG Top 50 Ocean Travel Agency 2022
TTG Top 50 Ocean Travel Agency 2022
Best Online Agent 2021
Best Online Agent 2021
Best Company 2020
Best Company 2020
Best Online Agent 2019
Best Online Agent 2019
TTG Top 50 Travel Agency 2019
TTG Top 50 Travel Agency 2019
Explore
Blog
About Us
Careers
Contact Us
Cruise118 Brochures
Frequently Asked Questions
Privacy Policy
Terms and Conditions
Marketing Preferences
Modern Slavery Statement
Cruise Deals
Cruise Deals
Fly Cruise Deals
2026 Cruises
2027 Cruises
All Inclusive Deals
Last Minute Cruise Deals
Cheap Cruise Deals
Family Cruises
Short Cruises
Adult Only Cruises
Cruise Lines
Ambassador Cruise Line
Celebrity Cruises
Disney Cruise Line
Fred Olsen Cruise Lines
MSC Cruises
Norwegian Cruise Line
P&O Cruises
Princess Cruises
Royal Caribbean International
Virgin Voyages
All Cruise Lines
Popular Ships
Celebrity Apex
MSC Virtuosa
MSC Euribia
MSC World Europa
Arvia
Britannia
Iona
Sky Princess
Icon of The Seas
Destinations
Caribbean
Italy
Mediterranean
South America
United Kingdom
All Destinations
Cyber Essentials Plus logo ABTA member
follow us
World Travel Holdings
This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
You've added to your wishlist. To view, go to Wishlist
Call for Free