P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 420 cruises
Per Person
Total Price

Sails from the UK

Cruise From:
Was £449pp Now: £435pp

Southampton | Cherbourg | Vigo | La Coruña | Getxo | Southampton

  • 18 Jan 2027
  • 7 Nights
Cruise From:
Was £449pp Now: £435pp
Holiday ID: 035654

Sails from the UK

Cruise From:
Was £449pp Now: £435pp

Southampton | Rotterdam | Southampton

  • 28 Aug 2028
  • 4 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £449pp Now: £435pp
Holiday ID: 081101

Sails from the UK

Cruise From:
Was £454pp Now: £440pp

Southampton | Zeebrugge | Amsterdam | Southampton

  • 11 Dec 2027
  • 5 Nights

Interest free Monthly Payments from JUST £44pp

Cruise From:
Was £454pp Now: £440pp
Holiday ID: 049328

Sails from the UK

Cruise From:
Was £454pp Now: £440pp

Southampton | Rotterdam | Zeebrugge | Southampton

  • 29 May 2028
  • 4 Nights

Interest free Monthly Payments from JUST £27pp

Cruise From:
Was £454pp Now: £440pp
Holiday ID: 081138

Sails from the UK

Cruise From:
Was £464pp Now: £450pp

Southampton | Hamburg | Zeebrugge | Southampton

  • 16 Jul 2027
  • 5 Nights

Interest free Monthly Payments from JUST £94pp

Cruise From:
Was £464pp Now: £450pp
Holiday ID: 032643

Sails from the UK

Cruise From:
Was £464pp Now: £450pp

Southampton | Le Havre | Hamburg | Southampton

  • 01 Dec 2027
  • 6 Nights

Interest free Monthly Payments from JUST £46pp

Cruise From:
Was £464pp Now: £450pp
Holiday ID: 049217

Sails from the UK

Cruise From:
Was £474pp Now: £459pp

Southampton | Amsterdam | Southampton

  • 08 Jun 2027
  • 4 Nights

Interest free Monthly Payments from JUST £138pp

Cruise From:
Was £474pp Now: £459pp
Holiday ID: 032621

Sails from the UK

Cruise From:
Was £474pp Now: £459pp

Southampton | Rotterdam | Zeebrugge | Southampton

  • 01 Aug 2028
  • 4 Nights

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £474pp Now: £459pp
Holiday ID: 081218

Sails from the UK

Cruise From:
Was £479pp Now: £464pp

Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton

  • 20 Feb 2027
  • 7 Nights
Cruise From:
Was £479pp Now: £464pp
Holiday ID: 015062

Sails from the UK

Cruise From:
Was £494pp Now: £479pp

Southampton | Amsterdam | Southampton

  • 21 Aug 2027
  • 4 Nights

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £494pp Now: £479pp
Holiday ID: 032629

Sails from the UK

Cruise From:
Was £499pp Now: £484pp

Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton

  • 13 Feb 2027
  • 7 Nights
Cruise From:
Was £499pp Now: £484pp
Holiday ID: 015061

Sails from the UK

Cruise From:
Was £499pp Now: £484pp

Southampton | Le Havre | Southampton

  • 31 May 2029
  • 4 Nights

Interest free Monthly Payments from JUST £17pp

Cruise From:
Was £499pp Now: £484pp
Holiday ID: 107196

Sails from the UK

Cruise From:
Was £499pp Now: £484pp

Southampton | Amsterdam | Zeebrugge | Southampton

  • 09 Dec 2028
  • 5 Nights

Interest free Monthly Payments from JUST £21pp

Cruise From:
Was £499pp Now: £484pp
Holiday ID: 107247

Sails from the UK

Cruise From:
Was £499pp Now: £484pp

Southampton | Copenhagen | Skagen | Kristiansand | Southampton

  • 19 Jan 2029
  • 7 Nights

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £499pp Now: £484pp
Holiday ID: 107253

Sails from the UK

Cruise From:
Was £504pp Now: £488pp

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 23 May 2027
  • 7 Nights

Interest free Monthly Payments from JUST £177pp

Cruise From:
Was £504pp Now: £488pp
Holiday ID: 032603

Sails from the UK

Cruise From:
Was £504pp Now: £488pp

Southampton | Vigo | La Coruña | Gijón | Getxo | Southampton

  • 30 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £57pp

Cruise From:
Was £504pp Now: £488pp
Holiday ID: 049324

Sails from the UK

Cruise From:
Was £504pp Now: £488pp

Southampton | Rotterdam | Zeebrugge | Southampton

  • 21 Sep 2028
  • 5 Nights

Interest free Monthly Payments from JUST £24pp

Cruise From:
Was £504pp Now: £488pp
Holiday ID: 081147

Sails from the UK

Cruise From:
Was £504pp Now: £488pp

Southampton | Zeebrugge | Cherbourg | Southampton

  • 29 Sep 2028
  • 5 Nights

Interest free Monthly Payments from JUST £24pp

Cruise From:
Was £504pp Now: £488pp
Holiday ID: 081238

Sails from the UK

Cruise From:
Was £514pp Now: £498pp

Southampton | Zeebrugge | Rotterdam | Southampton

  • 27 Aug 2027
  • 5 Nights

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £514pp Now: £498pp
Holiday ID: 032597

Sails from the UK

Cruise From:
Was £524pp Now: £508pp

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 07 May 2027
  • 7 Nights

Interest free Monthly Payments from JUST £233pp

Cruise From:
Was £524pp Now: £508pp
Holiday ID: 032543

Sails from the UK

Cruise From:
Was £524pp Now: £508pp

Southampton | Hamburg | Southampton

  • 15 Oct 2028
  • 5 Nights

Interest free Monthly Payments from JUST £24pp

Cruise From:
Was £524pp Now: £508pp
Holiday ID: 081205

Sails from the UK

Cruise From:
Was £529pp Now: £513pp

Southampton | Vigo | La Coruña | Gijón | Getxo | Southampton

  • 25 Nov 2028
  • 7 Nights

Interest free Monthly Payments from JUST £23pp

Cruise From:
Was £529pp Now: £513pp
Holiday ID: 107245

Sails from the UK

Cruise From:
Was £529pp Now: £513pp

Southampton | Hamburg | Rotterdam | Zeebrugge | Southampton

  • 30 Jan 2029
  • 7 Nights

Interest free Monthly Payments from JUST £21pp

Cruise From:
Was £529pp Now: £513pp
Holiday ID: 107255

Sails from the UK

Cruise From:
Was £534pp Now: £517pp

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 08 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £66pp

Cruise From:
Was £534pp Now: £517pp
Holiday ID: 032559

Sails from the UK

Cruise From:
Was £534pp Now: £517pp

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 06 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £534pp Now: £517pp
Holiday ID: 081106

Sails from the UK

Cruise From:
Was £534pp Now: £517pp

Southampton | Getxo | Le Verdon-sur-Mer | Le Havre | Southampton

  • 08 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £534pp Now: £517pp
Holiday ID: 081204

Sails from the UK

Cruise From:
Was £544pp Now: £527pp

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 15 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £65pp

Cruise From:
Was £544pp Now: £527pp
Holiday ID: 032613

Sails from the UK

Cruise From:
Was £544pp Now: £527pp

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 14 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £25pp

Cruise From:
Was £544pp Now: £527pp
Holiday ID: 081135

Sails from the UK

Cruise From:
Was £544pp Now: £527pp

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 01 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £26pp

Cruise From:
Was £544pp Now: £527pp
Holiday ID: 081203

Sails from the UK

Cruise From:
Was £554pp Now: £537pp

Southampton | Hamburg | Rotterdam | Zeebrugge | Southampton

  • 27 Mar 2027
  • 7 Nights
Cruise From:
Was £554pp Now: £537pp
Holiday ID: 015065

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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