P&O Cruises to the Mediterranean

Showing 30 out of 605 cruises
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Fly Cruise From:
Was £749pp Now: £726pp

Canary Islands and Madeira

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife

  • 10 Mar 2029
  • 7 Nights

Interest free Monthly Payments from JUST £28pp

Fly Cruise From:
Was £749pp Now: £726pp
View cruise
Holiday ID: 107133

Sails from the UK

Cruise From:
Was £754pp Now: £731pp

Portugal and Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Southampton

  • 19 Mar 2027
  • 12 Nights
Cruise From:
Was £754pp Now: £731pp
View cruise
Holiday ID: 015118
Fly Cruise From:
Was £754pp Now: £731pp

Western Mediterranean Fly-Cruise

Valletta | Marseille | Livorno | Civitavecchia | Valletta

  • 05 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £35pp

Fly Cruise From:
Was £754pp Now: £731pp
View cruise
Holiday ID: 081084

Sails from the UK

Cruise From:
Was £754pp Now: £731pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 16 Jul 2028
  • 7 Nights

Interest free Monthly Payments from JUST £41pp

Cruise From:
Was £754pp Now: £731pp
View cruise
Holiday ID: 081182
Fly Cruise From:
Was £764pp Now: £741pp

Eastern Mediterranean Fly-Cruise

Valletta | Piraeus | Katakolon | Sarandë | Cephalonia | Valletta

  • 24 Jun 2027
  • 7 Nights

Interest free Monthly Payments from JUST £187pp

Fly Cruise From:
Was £764pp Now: £741pp
View cruise
Holiday ID: 032508
Fly Cruise From:
Was £774pp Now: £750pp

Eastern Mediterranean Fly-Cruise

Valletta | Piraeus | Katakolon | Sarandë | Cephalonia | Valletta

  • 06 May 2027
  • 7 Nights
Fly Cruise From:
Was £774pp Now: £750pp
View cruise
Holiday ID: 032494
Fly Cruise From:
Was £774pp Now: £750pp

Greek Islands Fly-Cruise

Valletta | Piraeus | Suda Bay | Katakolon | Valletta

  • 14 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £93pp

Fly Cruise From:
Was £774pp Now: £750pp
View cruise
Holiday ID: 032540

Sails from the UK

Cruise From:
Was £774pp Now: £750pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 08 Jan 2028
  • 14 Nights

Interest free Monthly Payments from JUST £68pp

Cruise From:
Was £774pp Now: £750pp
View cruise
Holiday ID: 049333

Sails from the UK

Cruise From:
Was £774pp Now: £750pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 25 Jan 2028
  • 14 Nights

Interest free Monthly Payments from JUST £64pp

Cruise From:
Was £774pp Now: £750pp
View cruise
Holiday ID: 049335
Fly Cruise From:
Was £774pp Now: £750pp

Central Mediterranean Fly-Cruise

Valletta | Split | Zadar | Dubrovnik | Valletta

  • 06 Apr 2028
  • 7 Nights

Interest free Monthly Payments from JUST £52pp

Fly Cruise From:
Was £774pp Now: £750pp
View cruise
Holiday ID: 081032

Sails from the UK

Cruise From:
Was £774pp Now: £750pp

Spain And Portugal

Southampton | Vigo | Lisbon | Leixões | La Coruña | Southampton

  • 05 Aug 2028
  • 7 Nights

Interest free Monthly Payments from JUST £40pp

Cruise From:
Was £774pp Now: £750pp
View cruise
Holiday ID: 081219
Fly Cruise From:
Was £779pp Now: £755pp

Central Mediterranean

Valletta | Zadar | Split | Dubrovnik | Valletta

  • 19 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £35pp

Fly Cruise From:
Was £779pp Now: £755pp
View cruise
Holiday ID: 107056
Fly Cruise From:
Was £779pp Now: £755pp

Western Mediterranean

Valletta | Marseille | Livorno | Civitavecchia | Valletta

  • 26 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £35pp

Fly Cruise From:
Was £779pp Now: £755pp
View cruise
Holiday ID: 107058
Fly Cruise From:
Was £779pp Now: £755pp

New Year in Madeira and Canary Islands

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 30 Dec 2028
  • 7 Nights

Interest free Monthly Payments from JUST £32pp

Fly Cruise From:
Was £779pp Now: £755pp
View cruise
Holiday ID: 107093

Sails from the UK

Cruise From:
Was £779pp Now: £755pp

Portugal and Canary Islands

Southampton | Lisbon | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Funchal | Southampton

  • 09 Nov 2028
  • 12 Nights

Interest free Monthly Payments from JUST £34pp

Cruise From:
Was £779pp Now: £755pp
View cruise
Holiday ID: 107186
Fly Cruise From:
Was £784pp Now: £760pp

Western Mediterranean Fly-Cruise

Valletta | Civitavecchia | Livorno | Villefranche-sur-Mer | Ajaccio | Valletta

  • 26 Aug 2027
  • 7 Nights

Interest free Monthly Payments from JUST £121pp

Fly Cruise From:
Was £784pp Now: £760pp
View cruise
Holiday ID: 032526

Sails from the UK

Cruise From:
Was £784pp Now: £760pp

Spain And France

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 20 Aug 2027
  • 7 Nights

Interest free Monthly Payments from JUST £126pp

Cruise From:
Was £784pp Now: £760pp
View cruise
Holiday ID: 032554
Fly Cruise From:
Was £784pp Now: £760pp

Central Mediterranean Fly-Cruise

Valletta | Taranto | Corfu | Bari | Catania | Valletta

  • 11 May 2028
  • 7 Nights

Interest free Monthly Payments from JUST £49pp

Fly Cruise From:
Was £784pp Now: £760pp
View cruise
Holiday ID: 081042
Fly Cruise From:
Was £794pp Now: £770pp

Western Mediterranean Fly-Cruise

Valletta | Marseille | Livorno | Civitavecchia | Valletta

  • 07 Oct 2027
  • 7 Nights

Interest free Monthly Payments from JUST £99pp

Fly Cruise From:
Was £794pp Now: £770pp
View cruise
Holiday ID: 032538
Fly Cruise From:
Was £794pp Now: £770pp

Greek Islands Fly-Cruise

Valletta | Piraeus | Suda Bay | Katakolon | Valletta

  • 12 Oct 2028
  • 7 Nights

Interest free Monthly Payments from JUST £37pp

Fly Cruise From:
Was £794pp Now: £770pp
View cruise
Holiday ID: 081086
Fly Cruise From:
Was £799pp Now: £775pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 05 Dec 2026
  • 14 Nights
Fly Cruise From:
Was £799pp Now: £775pp
View cruise
Holiday ID: 014980
Fly Cruise From:
Was £799pp Now: £775pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 29 Jan 2027
  • 14 Nights
Fly Cruise From:
Was £799pp Now: £775pp
View cruise
Holiday ID: 015006
Fly Cruise From:
Was £799pp Now: £775pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife

  • 06 Feb 2027
  • 14 Nights
Fly Cruise From:
Was £799pp Now: £775pp
View cruise
Holiday ID: 015012
Fly Cruise From:
Was £799pp Now: £775pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife

  • 13 Feb 2027
  • 7 Nights
Fly Cruise From:
Was £799pp Now: £775pp
View cruise
Holiday ID: 015015
Fly Cruise From:
Was £799pp Now: £775pp

New Year in Madeira and Canary Islands

Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria

  • 28 Dec 2028
  • 7 Nights

Interest free Monthly Payments from JUST £33pp

Fly Cruise From:
Was £799pp Now: £775pp
View cruise
Holiday ID: 107091
Fly Cruise From:
Was £804pp Now: £779pp

Canary Islands and Mediterranean

Santa Cruz de Tenerife | Cádiz | Gibraltar | Valencia | Barcelona | Naples | Palermo | Valletta

  • 19 Mar 2027
  • 13 Nights
Fly Cruise From:
Was £804pp Now: £779pp
View cruise
Holiday ID: 015033
Fly Cruise From:
Was £804pp Now: £779pp

Greek Islands Fly-Cruise

Valletta | Piraeus | Suda Bay | Katakolon | Valletta

  • 23 Sep 2027
  • 7 Nights

Interest free Monthly Payments from JUST £107pp

Fly Cruise From:
Was £804pp Now: £779pp
View cruise
Holiday ID: 032534
Fly Cruise From:
Was £804pp Now: £779pp

Mediterranean And Canary Islands

Valletta | Cartagena | Málaga | Lanzarote | Santa Cruz de Tenerife

  • 21 Oct 2027
  • 9 Nights

Interest free Monthly Payments from JUST £94pp

Fly Cruise From:
Was £804pp Now: £779pp
View cruise
Holiday ID: 049133
Fly Cruise From:
Was £814pp Now: £789pp

Central Mediterranean Fly-Cruise

Valletta | Taranto | Corfu | Cephalonia | Catania | Valletta

  • 12 Aug 2027
  • 7 Nights

Interest free Monthly Payments from JUST £137pp

Fly Cruise From:
Was £814pp Now: £789pp
View cruise
Holiday ID: 032522

Sails from the UK

Cruise From:
Was £819pp Now: £794pp

Portugal and Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Southampton

  • 17 Nov 2026
  • 12 Nights
Cruise From:
Was £819pp Now: £794pp
View cruise
Holiday ID: 015112

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.


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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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