Mediterranean Cruises from Southampton

Cruises From Southampton > Mediterranean Cruises from Southampton

Discover amazing Mediterranean cruises from all of our amazing cruise lines. Explore our selection of Mediterranean cruises from Southampton to avoid the need and hassle of airports. Mediterranean cruises from Southampton provide an unforgettable experience that allows you to explore the beautiful sights and cities of our European cruise destinations. Book using our cruise deals to find great cruises to the Mediterranean for a great price.

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Looking for the best cruise deals on our Mediterranean cruises from Southampton? Book your cruise deal online with Cruise118 and guarantee the best possible price on all Mediterranean cruises from Southampton.

Showing 30 out of 483 cruises
Per Person
Total Price

Sails from the UK

Cruise From:
Was £1799pp Now: £1745pp

Southampton | Tangier | Tarragona | Civitavecchia | Olbia | Cartagena | Gibraltar | Southampton

  • 01 Sep 2028
  • 14 Nights

Interest free Monthly Payments from JUST £84pp

Cruise From:
Was £1799pp Now: £1745pp
Holiday ID: 084451

Sails from the UK

Cruise From:
Was £1799pp Now: £1745pp

Southampton | La Coruña | Tangier | Casablanca | Agadir | Funchal | Southampton

  • 29 Nov 2028
  • 14 Nights

Interest free Monthly Payments from JUST £72pp

Cruise From:
Was £1799pp Now: £1745pp
Holiday ID: 084457
Fly Cruise From:
Was £1799pp Now: £1745pp

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Saint Kitts | Dominica | Tortola | Sint Maarten | Saint John's

  • 20 Oct 2028
  • 22 Nights

Interest free Monthly Payments from JUST £81pp

Fly Cruise From:
Was £1799pp Now: £1745pp
Holiday ID: 107205

Sails from the UK

Cruise From:
Was £1799pp Now: £1745pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lisbon | Southampton

  • 21 Jan 2029
  • 14 Nights

Interest free Monthly Payments from JUST £66pp

Cruise From:
Was £1799pp Now: £1745pp
Holiday ID: 108009

Sails from the UK

Cruise From:
Was £1804pp Now: £1749pp

Southampton | Málaga | Cagliari | Cephalonia | Katakolon | Piraeus | Mykonos | Valletta | Palma de Mallorca | Cádiz | Southampton

  • 11 Apr 2028
  • 21 Nights

Interest free Monthly Payments from JUST £120pp

Cruise From:
Was £1804pp Now: £1749pp
Holiday ID: 081227

Sails from the UK

Cruise From:
Was £1824pp Now: £1751pp

Southampton | Cádiz | Barcelona | La Seyne-sur-Mer | Livorno | Ajaccio | Alghero | Ibiza | Cartagena | Southampton

  • 30 Apr 2027
  • 15 Nights
Cruise From:
Was £1824pp Now: £1751pp
Holiday ID: 064301

Sails from the UK

Cruise From:
Was £1814pp Now: £1759pp

Southampton | Vigo | Cádiz | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lisbon | Southampton

  • 21 Dec 2027
  • 16 Nights

Interest free Monthly Payments from JUST £167pp

Cruise From:
Was £1814pp Now: £1759pp
Holiday ID: 049270

Sails from the UK

Cruise From:
Was £1799pp Now: £1763pp

Southampton | Gibraltar | Arrecife | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Santa Cruz de La Palma | Funchal | Leixões | Southampton

  • 23 Nov 2026
  • 15 Nights
Cruise From:
Was £1799pp Now: £1763pp
Holiday ID: 030997

Sails from the UK

Cruise From:
Was £1799pp Now: £1763pp

Southampton | Gibraltar | Barcelona | Ajaccio | Civitavecchia | La Spezia | Cartagena | Lisbon | Southampton

  • 18 Nov 2027
  • 16 Nights

Interest free Monthly Payments from JUST £178pp

Cruise From:
Was £1799pp Now: £1763pp
Holiday ID: 090933
Fly Cruise From:
Was £1834pp Now: £1778pp

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Saint Kitts | Tortola | Sint Maarten | Dominica | Saint John's

  • 22 Oct 2027
  • 22 Nights

Interest free Monthly Payments from JUST £213pp

Fly Cruise From:
Was £1834pp Now: £1778pp
Holiday ID: 049285

Sails from the UK

Cruise From:
Was £1938pp Now: £1782pp

Southampton | Gijón | La Rochelle | Bilbao | Cherbourg | Southampton | Oslo | Fredericia | Copenhagen | Zeebrugge | Southampton

  • 04 Sep 2027
  • 14 Nights

Interest free Monthly Payments from JUST £245pp

Cruise From:
Was £1938pp Now: £1782pp
Holiday ID: 096332

Sails from the UK

Cruise From:
Was £1839pp Now: £1783pp

Southampton | Lisbon | Málaga | Valencia | Palma de Mallorca | Tarragona | Cádiz | Southampton

  • 24 Sep 2027
  • 14 Nights

Interest free Monthly Payments from JUST £230pp

Cruise From:
Was £1839pp Now: £1783pp
Holiday ID: 035329
Fly Cruise From:
Was £1844pp Now: £1788pp

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown | Saint Kitts | Tortola | Sint Maarten | Martinique | Saint John's

  • 30 Oct 2027
  • 21 Nights

Interest free Monthly Payments from JUST £207pp

Fly Cruise From:
Was £1844pp Now: £1788pp
Holiday ID: 049227

Sails from the UK

Cruise From:
Was £1879pp Now: £1822pp

Southampton | Praia da Vitória | Ponta Delgada | Funchal | Casablanca | Tangier | Lisbon | Southampton

  • 24 Oct 2027
  • 16 Nights

Interest free Monthly Payments from JUST £204pp

Cruise From:
Was £1879pp Now: £1822pp
Holiday ID: 035332

Sails from the UK

Cruise From:
Was £1879pp Now: £1822pp

Southampton | Santa Cruz de Tenerife | Sao Vicente Island | Praia | Lanzarote | Agadir | Cádiz | Lisbon | Southampton

  • 13 May 2029
  • 18 Nights

Interest free Monthly Payments from JUST £63pp

Cruise From:
Was £1879pp Now: £1822pp
Holiday ID: 107195

Sails from the UK

Cruise From:
Was £1899pp Now: £1842pp

Southampton | Funchal | Lanzarote | Fuerteventura | Santa Cruz de Tenerife | Santa Cruz de La Palma | Lisbon | Southampton

  • 20 Dec 2026
  • 14 Nights
Cruise From:
Was £1899pp Now: £1842pp
Holiday ID: 010241

Sails from the UK

Cruise From:
Was £1899pp Now: £1842pp

Southampton | Lisbon | Alicante | Barcelona | Civitavecchia | Naples | Messina | Cagliari | Málaga | Cádiz | Southampton

  • 09 May 2027
  • 18 Nights
Cruise From:
Was £1899pp Now: £1842pp
Holiday ID: 035146

Sails from the UK

Cruise From:
Was £1899pp Now: £1842pp

Southampton | La Coruña | Gibraltar | Málaga | Palma de Mallorca | Barcelona | Alicante | Cádiz | Southampton

  • 21 Jul 2028
  • 14 Nights

Interest free Monthly Payments from JUST £95pp

Cruise From:
Was £1899pp Now: £1842pp
Holiday ID: 084448

Sails from the UK

Cruise From:
Was £1899pp Now: £1842pp

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Southampton

  • 18 Feb 2029
  • 14 Nights

Interest free Monthly Payments from JUST £67pp

Cruise From:
Was £1899pp Now: £1842pp
Holiday ID: 108012

Sails from the UK

Cruise From:
Was £1924pp Now: £1866pp

Southampton | La Coruña | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Funchal | Southampton

  • 21 Dec 2027
  • 14 Nights

Interest free Monthly Payments from JUST £178pp

Cruise From:
Was £1924pp Now: £1866pp
Holiday ID: 049219

Sails from the UK

Cruise From:
Was £1954pp Now: £1895pp

Southampton | Lisbon | Alicante | Livorno | Civitavecchia | Cartagena | Casablanca | Tangier | Vigo | Southampton

  • 01 Sep 2027
  • 19 Nights
Cruise From:
Was £1954pp Now: £1895pp
Holiday ID: 032598

Sails from the UK

Cruise From:
Was £1964pp Now: £1899pp

Southampton | Motril | Palermo | Piraeus | Kusadasi | Santorini | Heraklion (Iraklion) | Cádiz | Southampton

  • 25 Apr 2027
  • 19 Nights
Cruise From:
Was £1964pp Now: £1899pp
Holiday ID: 032638

Sails from the UK

Cruise From:
Was £1969pp Now: £1899pp

Southampton | Praia da Vitória | Ponta Delgada | Agadir | Casablanca | Tangier | Lisbon | Southampton

  • 12 May 2027
  • 16 Nights
Cruise From:
Was £1969pp Now: £1899pp
Holiday ID: 035316

Sails from the UK

Cruise From:
Was £1979pp Now: £1919pp

Southampton | Vigo | Barcelona | Civitavecchia | Alghero | Málaga | Cádiz | Southampton

  • 31 Mar 2028
  • 14 Nights

Interest free Monthly Payments from JUST £128pp

Cruise From:
Was £1979pp Now: £1919pp
Holiday ID: 051788

Sails from the UK

Cruise From:
Was £1979pp Now: £1919pp

Southampton | Vigo | Cádiz | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal | Lisbon | Southampton

  • 21 Dec 2028
  • 16 Nights

Interest free Monthly Payments from JUST £81pp

Cruise From:
Was £1979pp Now: £1919pp
Holiday ID: 107189

Sails from the UK

Cruise From:
Was £2107pp Now: £1938pp

Southampton | Gijón | La Rochelle | Bilbao | Cherbourg | Southampton | Kirkwall | Skjolden | Nordfjordeid | Sandnes | Southampton

  • 29 May 2027
  • 14 Nights
Cruise From:
Was £2107pp Now: £1938pp
Holiday ID: 096329

Sails from the UK

Cruise From:
Was £1999pp Now: £1939pp

Southampton | Lisbon | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Funchal | Southampton

  • 15 Dec 2027
  • 13 Nights

Interest free Monthly Payments from JUST £178pp

Cruise From:
Was £1999pp Now: £1939pp
Holiday ID: 035336

Sails from the UK

Cruise From:
Was £1999pp Now: £1939pp

Southampton | Tangier | Tarragona | Palma de Mallorca | Palermo | La Goulette | Cagliari | Málaga | Cádiz | Southampton

  • 12 Mar 2027
  • 16 Nights
Cruise From:
Was £1999pp Now: £1939pp
Holiday ID: 048508

Sails from the UK

Cruise From:
Was £1999pp Now: £1939pp

Southampton | Cádiz | Barcelona | Marseille | Livorno | Málaga | Vigo | Southampton

  • 21 May 2028
  • 14 Nights

Interest free Monthly Payments from JUST £115pp

Cruise From:
Was £1999pp Now: £1939pp
Holiday ID: 084309

Sails from the UK

Cruise From:
Was £1999pp Now: £1939pp

Southampton | Praia da Vitória | Ponta Delgada | Funchal | Agadir | Casablanca | Cádiz | Southampton

  • 04 Oct 2028
  • 16 Nights

Interest free Monthly Payments from JUST £88pp

Cruise From:
Was £1999pp Now: £1939pp
Holiday ID: 084453

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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