Cruises To Italy From Southampton

Cruises From Southampton > Cruises To Italy From Southampton

Book your next cruise holiday at one of European Cruises premier cruise destinations. A cruise to Italy from Southampton allows you to enjoy the full cruise experience without the need for a fly cruise. Head on a cruise to Italy from Southampton and explore our cruise deals to allow you to save money on a great cruise line offering an unforgettable experience. With amazing cruise itineraries, you can soak up the rich culture of Italy and enjoy the comfort of your cruise ship.

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Looking for the best cruise deals on our cruises to Italy from Southampton? Book your cruise deal online with Cruise118.com

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Greece, Malta & Türkiye Cruise with Santorini Beach Club

Holiday prices from:
Was £1620pp Now: £1587pp

Greece, Malta & Türkiye Cruise with Santorini Beach Club

Piraeus | Santorini | Mykonos | Kusadasi | Valletta | Barcelona

  • 26 Jun 2027
  • 7 Nights
Holiday prices from:
Was £1620pp Now: £1587pp
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Panama Canal with Miami & Los Angeles Stay

Holiday prices from:
Was £2839pp Now: £2782pp

Panama Canal with Miami & Los Angeles Stay

Miami | Cartagena | Colón | Puntarenas | Puerto Quetzal | Cabo San Lucas | Los Angeles

  • 24 Mar 2027
  • 21 Nights
Holiday prices from:
Was £2839pp Now: £2782pp
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Cruise & Stay

Mediterranean, Greek Isles & Adriatic with Trieste Stay

Holiday prices from:
£1929pp

Mediterranean, Greek Isles & Adriatic with Trieste Stay

Trieste | Split | Kotor | Bay of Kotor | Corfu | Katakolon | Santorini | Khania | Rhodes | Limassol | Kusadasi | Athens

  • 22 Aug 2027
  • 13 Nights
  • Two-night 4* hotel stay in Trieste
  • Eleven-night full-board cruise
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1929pp
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Cruise & Stay

Hokkaido Cherry Blossoms with Tokyo Stay

Holiday prices from:
Was £2689pp Now: £2635pp

Hokkaido Cherry Blossoms with Tokyo Stay

Tokyo | Aomori | Muroran | Hakodate | Sakaiminato | Busan | Nagasaki | Kagoshima | Tokyo

  • 18 Apr 2027
  • 15 Nights
  • Eleven-night full-board cruise
  • Two-night 4* hotel stay in Tokyo
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
Was £2689pp Now: £2635pp
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Cruise & Stay

Western Caribbean & Mexico Cruise with Miami & Key West Stay

Holiday prices from:
Was £1989pp Now: £1949pp

Western Caribbean & Mexico Cruise with Miami & Key West Stay

Fort Lauderdale | Cozumel | Belize City | Roatán Island | Fort Lauderdale

  • 18 Jan 2027
  • 14 Nights
  • 4* hotel stays in Key West & Miami
  • 5-Day Car Hire
  • Seven-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1989pp Now: £1949pp
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Cruise & Stay

Grand Voyage Durban to Venice with African Safari

Holiday prices from:
Was £4699pp Now: £4599pp

Grand Voyage Durban to Venice with African Safari

Durban | Possession | Port Louis | Antsiranana | Nosy Ve | Port Victoria | 'Aqaba | Sharm El Sheikh | Rhodes | Heraklion (Iraklion) | Split | Venice

  • 25 Mar 2027
  • 33 Nights
  • Four-night at the Ivory Tree Game Lodge
  • Two-night 4* hotel stay in Durban
  • Direct return and internal flights with luggage allowance
  • 26-night full-board cruise
Holiday prices from:
Was £4699pp Now: £4599pp
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Cruise & Stay

Eastern Caribbean & Bahamas with Orlando & Miami Stay

Holiday prices from:
Was £1839pp Now: £1799pp

Eastern Caribbean & Bahamas with Orlando & Miami Stay

Fort Lauderdale | Grand Turk Island | Amber Cove | Celebration Key | Fort Lauderdale

  • 30 Jan 2027
  • 15 Nights
  • Return Trains from Miami to Orlando
  • 4* hotel stays in Orlando & Miami
  • Seven-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1839pp Now: £1799pp
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Cruise & Stay

Eastern Caribbean with Miami stay

Holiday prices from:
£1829pp

Eastern Caribbean with Miami stay

Miami | Saint Thomas | Saint Kitts | Sao Vicente Island | Bridgetown | Saint George's | Sint Maarten | Tortola | Miami

  • 07 Dec 2027
  • 17 Nights
  • Two-night 4* hotel stay in Miami
  • 14-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
£1829pp
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Cruise & Stay

Big Apple Stay + Bermuda & Caribbean Voyage

Holiday prices from:
£3089pp

Big Apple Stay + Bermuda & Caribbean Voyage

New York | Hamilton | Philipsburg | Road Town | San Juan (Puerto Rico)

  • 25 Oct 2027
  • 13 Nights
  • Nine-night More-Inclusive cruise
  • Three-night 4* hotel stay in New York
  • Return flights with luggage allowance
Holiday prices from:
£3089pp
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Cruise & Stay

Queensland Explorer

Holiday prices from:
£7216pp

Queensland Explorer

Brisbane | Airlie Beach | Yorkeys Knob | Brisbane

  • 02 Jan 2027
  • 25 Nights
  • Hotel stays in Melbourne, Yarra Valley, Geelong
  • Three-night Best of Uluru and Kings Canyon tour
  • Hotel stays in Brisbane and Noosa
  • Overseas transfers and car hire
Holiday prices from:
£7216pp
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Caribbean with Universal Orlando Tickets & Stay

Holiday prices from:
Was £1819pp Now: £1782pp

Caribbean with Universal Orlando Tickets & Stay

Port Canaveral | Great Stirrup Cay | Falmouth | Georgetown | Cozumel | Port Canaveral

  • 29 Nov 2026
  • 15 Nights
  • Return direct flights with luggage allowance
  • Seven-night 4* hotel stay in Orlando
  • Universal Orlando Park Tickets
  • Seven-night full-board cruise
Holiday prices from:
Was £1819pp Now: £1782pp
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Cruise & Stay

Southern Caribbean, Barbados and Antigua with San Juan Stay

Holiday prices from:
Was £2079pp Now: £2037pp

Southern Caribbean, Barbados and Antigua with San Juan Stay

San Juan (Puerto Rico) | Saint Thomas | Sint Maarten | Saint John's | Dominica | Bridgetown | San Juan (Puerto Rico)

  • 05 Feb 2027
  • 10 Nights
  • Two-night 4* hotel stay in San Juan
  • Seven-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £2079pp Now: £2037pp
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Caribbean Voyage with Universal Orlando Tickets & Stay

Holiday prices from:
£2735pp

Caribbean Voyage with Universal Orlando Tickets & Stay

Port Canaveral | Nassau | Georgetown | Falmouth | Great Stirrup Cay | Port Canaveral

  • 14 Feb 2027
  • 15 Nights
  • Direct return flights with luggage allowance
  • Seven-night 4* hotel stay at a Universal Resort Hotel
  • Universal Orlando Three Park Tickets
  • Seven-night full-board cruise
Holiday prices from:
£2735pp
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Cruise & Stay

Eastern Caribbean & St. Kitts with Miami stay

Holiday prices from:
£1579pp

Eastern Caribbean & St. Kitts with Miami stay

Fort Lauderdale | Amber Cove | San Juan (Puerto Rico) | Saint Kitts | Fort Lauderdale

  • 27 Oct 2027
  • 10 Nights
  • Seven-night full-board cruise
  • Two-night 4* hotel stay in Miami
  • Return flights with luggage allowance
Holiday prices from:
£1579pp
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Cruise & Stay

Pacific Wine Country & Los Angeles stay

Holiday prices from:
Was £1529pp Now: £1498pp

Pacific Wine Country & Los Angeles stay

Los Angeles | San Diego | San Francisco | Astoria | Victoria | Vancouver

  • 03 May 2027
  • 10 Nights
  • Two-night 4* hotel stay in Los Angeles
  • Seven-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1529pp Now: £1498pp
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French Riviera, Spain & Ibiza with Barcelona Stay

Holiday prices from:
Was £1199pp Now: £1175pp

French Riviera, Spain & Ibiza with Barcelona Stay

Barcelona | Cannes | Toulon | Valencia | Ibiza | Barcelona

  • 14 May 2027
  • 9 Nights
Holiday prices from:
Was £1199pp Now: £1175pp
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Cruise & Stay

Mexican Riviera with Los Angeles Stay

Holiday prices from:
£1489pp

Mexican Riviera with Los Angeles Stay

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 25 Nov 2027
  • 10 Nights
  • Two-night 4* hotel stay in Los Angeles
  • Seven-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
£1489pp
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Greek Isles & Mykonos with Athens Stay

Holiday prices from:
£1859pp

Greek Isles & Mykonos with Athens Stay

Piraeus | Santorini | Rhodes | Bodrum | Mykonos | Piraeus

  • 25 May 2028
  • 10 Nights
  • Return direct flights with luggage allowance
  • Three-night 4* hotel stay in Athens
  • Seven-night full-board cruise
  • Select private overseas transfers
Holiday prices from:
£1859pp
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Best Of Greece & Croatia with Athens Stay

Holiday prices from:
Was £1539pp Now: £1499pp

Best Of Greece & Croatia with Athens Stay

Piraeus | Split | Bar | Santorini | Mykonos | Piraeus

  • 11 Jun 2027
  • 9 Nights
Holiday prices from:
Was £1539pp Now: £1499pp
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Cruise & Stay

Cruise118.com Exclusive Savings! Mexican Riviera with San Francisco Stay

Holiday prices from:
£1649pp

Cruise118.com Exclusive Savings! Mexican Riviera with San Francisco Stay

San Francisco | San Diego | Ensenada | Los Angeles | Santa Barbara | San Francisco

  • 17 Mar 2028
  • 10 Nights
  • Two-night 4* hotel stay in San Francisco
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
Holiday prices from:
£1649pp
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Cruise & Stay

Japan Explorer Cherry Blossoms with Tokyo Stay

Holiday prices from:
Was £5099pp Now: £4997pp

Japan Explorer Cherry Blossoms with Tokyo Stay

Yokohama | Yatsushiro | Busan | Nagasaki | Kagoshima | Beppu | Matsuyama | Kochi | Osaka | Tokushima | Shimizu | Yokohama

  • 24 Mar 2027
  • 16 Nights
  • Twelve-night full board cruise
  • Two-night 4* hotel stay in Tokyo
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
Was £5099pp Now: £4997pp
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Cruise & Stay

Singapore & Hong Stay with Thailand & Vietnam Cruise

Holiday prices from:
£4689pp

Singapore & Hong Stay with Thailand & Vietnam Cruise

Singapore | Ko Samui | Laem Chabang | Phu My | Chan May | Ha Long Bay | Hong Kong

  • 21 Nov 2027
  • 20 Nights
  • Return flights from the UK
  • Three-night 4* hotel stay in Singapore
  • Three-night 5* hotel stay in Hong Kong
  • 12-night full-board cruise
Holiday prices from:
£4689pp
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Cruise & Stay

Superbowl weekend! LA & Las Vegas Stay with Ensenada Cruise

Holiday prices from:
£1752pp

Superbowl weekend! LA & Las Vegas Stay with Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 12 Feb 2027
  • 13 Nights
  • Direct return flights and internal flights with luggage
  • Three-night 4* hotel stay in LA
  • Five-night 5* hotel stay in Las Vegas
  • Four-night full board cruise
Holiday prices from:
£1752pp
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Cruise & Stay

Cruise118.com Exclusive Savings! Asia Delights with Singapore & Bali Stays

Holiday prices from:
£2699pp

Cruise118.com Exclusive Savings! Asia Delights with Singapore & Bali Stays

Singapore | Phuket | Georgetown | Langkawi Island | Port Klang | Cam Ranh | Phu My | Laem Chabang | Singapore

  • 17 Jan 2028
  • 23 Nights
  • 4* hotel stays in Singapore & Bali
  • 14-night full-board cruise
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£2699pp
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Cruise & Stay

Western Caribbean with New Orleans Stay

Holiday prices from:
£2009pp

Western Caribbean with New Orleans Stay

New Orleans | Cozumel | Roatán Island | Harvest Caye | Costa Maya | New Orleans

  • 18 Feb 2028
  • 10 Nights
  • Two-night 4* hotel stay in New Orleans
  • Return flights with luggage allowance
  • Seven-night full-board cruise
Holiday prices from:
£2009pp
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Cruise & Stay

Croatia Intensive Cruise: Zadar, Split & Dubrovnik with Venice Stay

Holiday prices from:
Was £4089pp Now: £3999pp

Croatia Intensive Cruise: Zadar, Split & Dubrovnik with Venice Stay

Fusina | Opatija | Zadar | Split | Korčula | Dubrovnik | Kotor | Khania | Athens

  • 18 Jun 2027
  • 11 Nights
  • Two-night 4* hotel stay in Venice
  • Nine-night All-Inclusive cruise
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
Was £4089pp Now: £3999pp
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Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Book Your Italy Cruise from Southampton For 2024 and Beyond

If you are looking for a 2024 cruise, then an Italy cruise from Southampton is the perfect choice. See stunning cities and beautiful scenery, and cruise through the Mediterranean Sea on a Mediterranean cruise. Find our cruise deals for 2025 if you want to book ahead and save on early booking discounts.

Experience A Cruise from Southampton

When you book a cruise from Southampton, you can head straight to your cruise destination without the need to board a flight. Our cruise deals on UK cruises allow you to save money and allow you to simply park up and board your Italy cruise from Southampton at the cruise terminal. 

Explore An All Inclusive Italy Cruise from Southampton

An all inclusive cruise holiday is the perfect way to cruise in luxury. Experience exclusive dining options and complimentary drinks, as well as amazing offshore excursions. When you save with our cruise deals, you can put the savings towards going all out on an all inclusive cruise.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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