Cruises To Italy From Southampton

Cruises From Southampton > Cruises To Italy From Southampton

Book your next cruise holiday at one of European Cruises premier cruise destinations. A cruise to Italy from Southampton allows you to enjoy the full cruise experience without the need for a fly cruise. Head on a cruise to Italy from Southampton and explore our cruise deals to allow you to save money on a great cruise line offering an unforgettable experience. With amazing cruise itineraries, you can soak up the rich culture of Italy and enjoy the comfort of your cruise ship.

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Looking for the best cruise deals on our cruises to Italy from Southampton? Book your cruise deal online with Cruise118.com

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Cruise & Stay

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Holiday prices from:
Was £1229pp Now: £1199pp

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Athens | Santorini | Bar | Corfu | Messina | Barcelona

  • 14 May 2027
  • 9 Nights
  • Two-night 4* hotel stay in Athens
  • Seven-night full-board cruise
  • Return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
Was £1229pp Now: £1199pp
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Cruise & Stay

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Holiday prices from:
£1329pp

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Athens | Heraklion (Iraklion) | Bar | Corfu | Messina | Barcelona

  • 27 Aug 2027
  • 9 Nights
  • Two-night 4* hotel stay in Athens
  • Seven-night full-board cruise
  • Return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
£1329pp
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Cruise & Stay

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Holiday prices from:
£1349pp

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Athens | Santorini | Bar | Corfu | Messina | Barcelona

  • 17 Sep 2027
  • 9 Nights
  • Seven-night full-board cruise
  • Two-night 4* hotel stay in Athens
  • Return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
£1349pp
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Cruise & Stay

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Holiday prices from:
£1279pp

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Athens | Santorini | Bar | Corfu | Messina | Barcelona

  • 08 Oct 2027
  • 9 Nights
  • Two-night 4* hotel stay in Athens
  • Seven-night full-board cruise
  • Return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
£1279pp
View cruise

Cruise & Stay

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Holiday prices from:
£1349pp

Cruise118.com Exclusive Savings! Mediterranean, Greece & Adriatic with Athens Stay

Athens | Santorini | Bar | Corfu | Messina | Barcelona

  • 29 Oct 2027
  • 9 Nights
  • Two-night 4* hotel stay in Athens
  • Seven-night full-board cruise
  • Return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
£1349pp
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Spain, Portugal & Morocco with Barcelona Stay

Holiday prices from:
Was £1434pp Now: £1399pp

Spain, Portugal & Morocco with Barcelona Stay

Barcelona | Málaga | Tangier | Lisbon | Leixões | Funchal | Cádiz | Barcelona

  • 18 Apr 2027
  • 13 Nights
Holiday prices from:
Was £1434pp Now: £1399pp
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Cruise & Stay

Vietnam & Hong Kong Discovery Cruise with Stays in Singapore & Hong Kong

Holiday prices from:
Was £2949pp Now: £2890pp

Vietnam & Hong Kong Discovery Cruise with Stays in Singapore & Hong Kong

Singapore | Ho Chi Minh City | Da Nang | Hong Kong

  • 21 Feb 2027
  • 13 Nights
  • 4* hotel stays in Singapore & Hong Kong
  • Seven-night more-inclusive cruise
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
Was £2949pp Now: £2890pp
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Greece, Malta & Türkiye Cruise with Santorini Beach Club

Holiday prices from:
Was £1620pp Now: £1587pp

Greece, Malta & Türkiye Cruise with Santorini Beach Club

Piraeus | Santorini | Mykonos | Kusadasi | Valletta | Barcelona

  • 26 Jun 2027
  • 7 Nights
Holiday prices from:
Was £1620pp Now: £1587pp
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Cruise & Stay

PRICE DROP! Eastern Caribbean with Turks & Caicos with Miami Stay

Holiday prices from:
Was £1399pp Now: £1371pp

PRICE DROP! Eastern Caribbean with Turks & Caicos with Miami Stay

Fort Lauderdale | Celebration Key | Amber Cove | Grand Turk Island | Fort Lauderdale

  • 04 Dec 2026
  • 9 Nights
  • Two-night 4* hotel stay in Miami
  • Six-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1399pp Now: £1371pp
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Cruise & Stay

Half-Term Escape: Turks & Caicos with Miami Stay

Holiday prices from:
Was £1769pp Now: £1733pp

Half-Term Escape: Turks & Caicos with Miami Stay

Fort Lauderdale | Celebration Key | Grand Turk Island | Nassau | Fort Lauderdale

  • 12 Feb 2027
  • 9 Nights
  • Based on a family of 3 sharing
  • Two-night 4* hotel stay in Miami
  • Six-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1769pp Now: £1733pp
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Cruise & Stay

PRICE DROP! Hawaiian Islands with Los Angeles Stay

Holiday prices from:
Was £1629pp Now: £1596pp

PRICE DROP! Hawaiian Islands with Los Angeles Stay

Los Angeles | Kahului-Maui | Hilo | Kailua-Kona | Honolulu | Ensenada | Los Angeles

  • 08 Feb 2027
  • 19 Nights
  • Two-night 4* hotel stay in Los Angeles
  • 16-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1629pp Now: £1596pp
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Cruise & Stay

PRICE DROP! Hawaiian Islands with San Francisco stay

Holiday prices from:
Was £1889pp Now: £1851pp

PRICE DROP! Hawaiian Islands with San Francisco stay

San Francisco | Kailua-Kona | Honolulu | Kahului-Maui | Ensenada | San Francisco

  • 09 Jan 2027
  • 19 Nights
  • Two-night 4* hotel stay in San Francisco
  • 16-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1889pp Now: £1851pp
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Cruise & Stay

PRICE DROP1 Hawaiian Islands Holiday with San Francisco stay

Holiday prices from:
Was £1829pp Now: £1792pp

PRICE DROP1 Hawaiian Islands Holiday with San Francisco stay

San Francisco | Hilo | Honolulu | Kahului-Maui | Nawiliwili | Ensenada | San Francisco

  • 24 Dec 2026
  • 19 Nights
  • Two-night 4* hotel stay in San Francisco
  • 16-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1829pp Now: £1792pp
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Cruise & Stay

PRICE DROP! Hawaiian Islands with Los Angeles Stay

Holiday prices from:
Was £1599pp Now: £1567pp

PRICE DROP! Hawaiian Islands with Los Angeles Stay

Los Angeles | Hilo | Honolulu | Nawiliwili | Kailua-Kona | Ensenada | Los Angeles

  • 24 Feb 2027
  • 19 Nights
  • Two-night 4* hotel stay in Los Angeles
  • 16-night full-board cruise
  • Return fights with luggage allowance
Holiday prices from:
Was £1599pp Now: £1567pp
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Cruise & Stay

PRICE DROP! Panama Canal with Costa Rica & Caribbean with Miami Stay

Holiday prices from:
Was £1399pp Now: £1371pp

PRICE DROP! Panama Canal with Costa Rica & Caribbean with Miami Stay

Fort Lauderdale | Curaçao | Cartagena | Colón | Cartagena | Puerto Limón | Celebration Key | Fort Lauderdale

  • 28 Oct 2026
  • 15 Nights
  • Return flights with luggage allowance
  • Two-night 4* hotel stay in Miami
  • 12-night full-board cruise
Holiday prices from:
Was £1399pp Now: £1371pp
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Cruise & Stay

PRICE DROP! Eastern Caribbean with Turks & Caicos with Orlando Stay

Holiday prices from:
Was £1599pp Now: £1567pp

PRICE DROP! Eastern Caribbean with Turks & Caicos with Orlando Stay

Port Canaveral | Celebration Key | Amber Cove | Grand Turk Island | Port Canaveral

  • 13 Feb 2027
  • 9 Nights
  • Six-night full-board cruise
  • Two-night 4* hotel stay in Orlando
  • Return flights with luggage allowance
Holiday prices from:
Was £1599pp Now: £1567pp
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Cruise & Stay

PRICE DROP! Eastern Caribbean & St. Kitts with Miami stay

Holiday prices from:
Was £1799pp Now: £1763pp

PRICE DROP! Eastern Caribbean & St. Kitts with Miami stay

Fort Lauderdale | Celebration Key | Amber Cove | San Juan (Puerto Rico) | Saint John's | Sint Maarten | Saint Kitts | Fort Lauderdale

  • 04 Jan 2027
  • 13 Nights
  • Two-night 4* hotel stay in Miami
  • Ten-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1799pp Now: £1763pp
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Cruise & Stay

PRICE DROP! Panama Canal, Costa Rica & Caribbean with Miami Stay

Holiday prices from:
Was £1599pp Now: £1567pp

PRICE DROP! Panama Canal, Costa Rica & Caribbean with Miami Stay

Fort Lauderdale | Curaçao | Cartagena | Colón | Cartagena | Puerto Limón | Celebration Key | Fort Lauderdale

  • 08 Jan 2027
  • 15 Nights
  • Two-night 4* hotel stay in Miami
  • 12-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1599pp Now: £1567pp
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Cruise & Stay

PRICE DROP! Hawaiian Islands with Los Angeles stay

Holiday prices from:
Was £1729pp Now: £1694pp

PRICE DROP! Hawaiian Islands with Los Angeles stay

Los Angeles | Hilo | Honolulu | Kailua-Kona | Nawiliwili | Ensenada | Los Angeles

  • 07 Jan 2027
  • 19 Nights
  • Two-night 4* hotel stay in Los Angeles
  • 16-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £1729pp Now: £1694pp
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Cruise & Stay

PRICE DROP! Caribbean Eastern Adventurer with Miami Stay

Holiday prices from:
Was £3279pp Now: £3213pp

PRICE DROP! Caribbean Eastern Adventurer with Miami Stay

Fort Lauderdale | Celebration Key | Grand Turk Island | Nassau | Fort Lauderdale | Amber Cove | San Juan (Puerto Rico) | Sint Maarten | Grand Turk Island | Fort Lauderdale

  • 18 Dec 2026
  • 17 Nights
  • Two-night 4* hotel stay in Miami
  • 14-night full-board cruise
  • Return flights with luggage allowance
Holiday prices from:
Was £3279pp Now: £3213pp
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Cruise & Stay

PRICE DROP! Eastern Caribbean & Puerto Rico with Orlando stay

Holiday prices from:
Was £1399pp Now: £1371pp

PRICE DROP! Eastern Caribbean & Puerto Rico with Orlando stay

Port Canaveral | Celebration Key | San Juan (Puerto Rico) | Amber Cove | Grand Turk Island | Port Canaveral

  • 22 Jan 2027
  • 11 Nights
  • Two-night 4* hotel stay in Orlando
  • Eight-night full-board cruise
  • Direct return flights with luggage allowance
Holiday prices from:
Was £1399pp Now: £1371pp
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Cruise & Stay

Japan Explorer Cherry Blossoms with Tokyo Stay

Holiday prices from:
Was £5099pp Now: £4997pp

Japan Explorer Cherry Blossoms with Tokyo Stay

Yokohama | Yatsushiro | Busan | Nagasaki | Kagoshima | Beppu | Matsuyama | Kochi | Osaka | Tokushima | Shimizu | Yokohama

  • 24 Mar 2027
  • 16 Nights
  • Twelve-night full board cruise
  • Two-night 4* hotel stay in Tokyo
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
Was £5099pp Now: £4997pp
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Cruise & Stay

Singapore & Hong Stay with Thailand & Vietnam Cruise

Holiday prices from:
£5719pp

Singapore & Hong Stay with Thailand & Vietnam Cruise

Singapore | Ko Samui | Laem Chabang | Phu My | Chan May | Ha Long Bay | Hong Kong

  • 21 Nov 2027
  • 20 Nights
  • Return flights from the UK
  • Three-night 4* hotel stay in Singapore
  • Three-night 5* hotel stay in Hong Kong
  • 12-night full-board cruise
Holiday prices from:
£5719pp
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Cruise & Stay

Superbowl weekend! LA & Las Vegas Stay with Ensenada Cruise

Holiday prices from:
£1752pp

Superbowl weekend! LA & Las Vegas Stay with Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 12 Feb 2027
  • 13 Nights
  • Direct return flights and internal flights with luggage
  • Three-night 4* hotel stay in LA
  • Five-night 5* hotel stay in Las Vegas
  • Four-night full board cruise
Holiday prices from:
£1752pp
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Cruise & Stay

Cruise118.com Exclusive Savings! Asia Delights with Singapore & Bali Stays

Holiday prices from:
£2769pp

Cruise118.com Exclusive Savings! Asia Delights with Singapore & Bali Stays

Singapore | Phuket | Georgetown | Langkawi Island | Port Klang | Cam Ranh | Phu My | Laem Chabang | Singapore

  • 17 Jan 2028
  • 23 Nights
  • 4* hotel stays in Singapore & Bali
  • 14-night full-board cruise
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£2769pp
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Cruise & Stay

Croatia Intensive Cruise: Zadar, Split & Dubrovnik with Venice Stay

Holiday prices from:
Was £4089pp Now: £3999pp

Croatia Intensive Cruise: Zadar, Split & Dubrovnik with Venice Stay

Fusina | Opatija | Zadar | Split | Korčula | Dubrovnik | Kotor | Khania | Athens

  • 18 Jun 2027
  • 11 Nights
  • Two-night 4* hotel stay in Venice
  • Nine-night All-Inclusive cruise
  • Return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
Was £4089pp Now: £3999pp
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Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Book Your Italy Cruise from Southampton For 2024 and Beyond

If you are looking for a 2024 cruise, then an Italy cruise from Southampton is the perfect choice. See stunning cities and beautiful scenery, and cruise through the Mediterranean Sea on a Mediterranean cruise. Find our cruise deals for 2025 if you want to book ahead and save on early booking discounts.

Experience A Cruise from Southampton

When you book a cruise from Southampton, you can head straight to your cruise destination without the need to board a flight. Our cruise deals on UK cruises allow you to save money and allow you to simply park up and board your Italy cruise from Southampton at the cruise terminal. 

Explore An All Inclusive Italy Cruise from Southampton

An all inclusive cruise holiday is the perfect way to cruise in luxury. Experience exclusive dining options and complimentary drinks, as well as amazing offshore excursions. When you save with our cruise deals, you can put the savings towards going all out on an all inclusive cruise.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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